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    Using Yeast to Make Scientists: A Six-Week Student-Driven Research Project for the Cell Biology Laboratory
    Traditionally-trained undergraduate students often lack an understanding of science as an active process that yields the information presented in their textbooks. One result has been a call for...

    Keywords: yeastgrowth curvecell proliferationviability

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    Pesticides in My Smoothie Bowl?
    Teaching resources, especially active learning pedagogy, are scarce for toxicology compared to what is available for other disciplines. Ecological and human health risk assessment are...

    Keywords: data analysistoxicologychemical toxicityecological risk assessmenthuman risk assessmentpesticide

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    Glycolysis Can Be Fun: Rediscovering Glycolysis as a Problem-Solving Introduction to Metabolism
    A thorough understanding of glycolysis forms a foundation for students to analyze subsequent topics in metabolism, a core competency recognized by multiple national societies for biology and...

    Keywords: Problem based learningPOGILenzymesGlycolysisMetabolismFermentationchemical reactionsCard sorting activityCofactors

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    5-007-ChemOpt-ModelingScenario
    Modeling a chemical reaction and estimating parameters in the model permits optimization of profits from extracting reactants.

    Keywords: optimizationpYield and sustainabilitynonprofit managementLaw of Mass Actionkineticreaction

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    2007-Ramsay-Hooker-Campbell-Cao-Parameter estimation for differential equations-a generalized smoothing approach
    We propose a new method for estimating parameters in models that are defined by a system of non-linear differential equations.

    Keywords: estimating equationfunctional data analysisGauss–Newton methodparameter cascadeprofiled estimationdynamic system

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    1967-Israelsson- Johnsson-Circumnutations In Helianthus Annuus
    A theory is given for circumnutations in plants, especially hypocotyls of Helianthus annuus, which were used as experimental material.

    Keywords: plantoscillationdelaycircumnutationturning

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    2018-Robert_Phair-Differential_equation_methods_for_simulation_of_GFP_kinetics_in_non–steady_state_experiments
    Here, we derive new tracer kinetic analytical methods for non–steady state biological systems by constructing mechanistic nonlinear differential equation models of the underlying cell biological...

    Keywords: protein quality controlkineticsCellssteady statechemical kineticsfluouresencephotoactivationinytracellular

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    Happy Blue Baby
    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved on its own...

    Keywords: mutationHemoglobinmolecular visualization and analysisgenetic basisPDBMolecular Case StudyMol*

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    Waking up Anna - Adaptations and Conversion to Mol*
    This case focuses on understanding the molecular basis of Anna's sleeping disorder and its treatment. The adaptations addressed question clarity and reformatting to use Mol*.

    Keywords: sleepmolecular visualization and analysisPDBMolecular Case StudyGABAMolCaseNetMol*MolStarProtein visualizationFlumazenil

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    The Happy Blue Baby Hemoglobin
    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved.

    Keywords: mutationHemoglobinmolecular visualization and analysisPDBMolecular Case Study

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    Waking up Anna
    This case focuses on understanding the molecular basis of Anna's sleeping disorder and its treatment.

    Keywords: sleepmolecular visualization and analysisPDBMolecular Case StudyGABA

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    The nose knows: How tri-trophic interactions and natural history shape bird foraging behavior. An introduction to statistical analysis in animal behavior research
    Students investigate the role of olfaction and infochemicals on bird foraging behavior through two different quantitative activities where they generate hypotheses, create figures, conduct data...

    Keywords: Resources @ ESA - TIEEforagingfmnanimal behaviorbehavioral ecologyDIGtrophic cascades

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    Using a Sequential Interpretation of Data in Envelopes (SIDE) approach to identify a mystery TRP channel
    This lesson sought to engage students in data interpretation and to encourage critical thinking about neurophysiology in the context of temperature sensation. A family of receptors called Transient...

    Keywords: Cell communicationChannel specificity and activationLimitations of tools of Cell BiologyNeuronal Signaling

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    2012-Brian_Ingalls-Mathematical Modelling in Systems Biology An Introduction
    This is a comprehensive text with much biology background to motivate the mathematical modeling, exercises and answers, and many rich examples.

    Keywords: spatialsensitivity analysisgene regulatory networksstochasticbifurcationmetabolic networkselectrophysiologytransductionrate lawsbiochemical reactions

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    Evaluating the potential for immune escape: how likely is an antibody to protect against a specific SARS-CoV-2 variant?
    Commercial antibodies to the SARS-CoV-2 spike protein have been successfully used to treat people with COVID-19. Unfortunately, as the SARS-CoV-2 virus evolves, new variants have appeared that can...

    Keywords: course based undergraduate research experiencesBLASTmolecular modelingSARS-CoV-2antibodyNextstrainiCn3DSequence alignmentStructure alignment

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    2011-Nancy_Rodrıguez-Applied Partial Differential Equations in Crime Modeling and Biological Aggregation
    In the first part we study a fully-parabolic system of PDEs for residential burglary ‘hotspots’ (spatio-temporal areas of high density of crime). In this work we are concerned with the existence...

    Keywords: biologyDiffusionKeller-Segel modelchemotaxiscrime

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    1984-Marguerite_Hays-Compartmental Models for Human Iodine Metabolism
    Compartmental models for the various aspects of human iodine metabolism are reviewed, emphasizing the role of Mones Berman in the development of this field.

    Keywords: compartment modeliodinethyroid

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    1972-R_C_Rothermel-A Mathematical Model for Predicting Fire Spread in Wildland Fuels
    The development of a mathematical model for predicting rate of fire spread and intensity applicable to a wide range of wildland fuels is presented from the conceptual stage through evaluation and...

    Keywords: predictionforest firefire managementfire spreadfuel

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    Evaluating the potential for immune escape: how likely is an antibody to protect against a specific SARS-CoV-2 variant?
    Commercial antibodies to the SARS-CoV-2 spike protein have been successfully used to treat people with COVID-19. Unfortunately, as the SARS-CoV-2 virus evolves, new variants have appeared that can...

    Keywords: course based undergraduate research experiencesBLASTmolecular modelingSARS-CoV-2antibodyNextstrainiCn3DSequence alignmentStructure alignment

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    Disease Spread Simulation with M&M's and Information on the wider SIMIODE community
    This is a Student Version of a Modeling Scenario from the community, SIMIODE - Systemic Initiative for Modeling Investigations and Opportunities with Differential Equations at www.simiode.org

    Keywords: resourcesdifferential equationsmodelingsimulationmoduledataepidemicsdiseasecommunityapplied mathematicsResources @ SIMIODEretinal surgeryinsect colonyLSDm&mparameter estimationin-class activityproject

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