QUBES will have scheduled maintenance work beginning on Wednesday, June 26, 2024, 4pm ET/1pm PT. The platform will operate normally for most of the day, except for an extended outage period lasting no more than 4 hours. All running tool sessions will expire during the maintenance window. Please plan accordingly and we do apologize for any inconvenience. close

You are here: Home / Resources / Browse Resources

Open. Adaptable. Free.

Resources created by our members and partners.

The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

Text Search:
Applied Filters
    Hardy-Weinberg Equilibrium
    This module introduces the Hardy-Weinberg model in the context of understanding the population's genotype and allele frequencies. It is intended for an introductory biology audience.

    Keywords: genotypeallelesGenetics and EvolutionFrequenciesHardy-Weinberg model

    858

    views

    318

    downloads

    0

    comments

    0

    adaptations

    Population Genetics: Limits to Adaptation
    This module introduces gene flow in the context of understanding the persistence of maladaptive traits in some populations. It is intended for an introductory biology audience.

    Keywords: LogarithmsAlgebraGenetics and Evolution

    782

    views

    172

    downloads

    0

    comments

    0

    adaptations

    Using Undergraduate Molecular Biology Labs to Discover Targets of miRNAs in Humans
    In this lesson, we describe an easily adaptable lab module that can be used in existing undergraduate molecular biology lab courses to conduct authentic scientific research, published in CourseSource

    Keywords: molecular biologybioinformaticsNIBLSEgene regulationmicroRNAsgene expressionCourseSourcemiRNA

    1472

    views

    349

    downloads

    0

    comments

    0

    adaptations

    Introduction to Mathematical Modeling in Biotechnology, Cell Biology, and Physiology
    The course is a mathematical and computational exploration of five diverse areas of biology: human locomotion, gene sequence analysis, signal transduction pathways involved in cancer,...

    Keywords: mathematical modelingcoursehuman locomotionneuroanatomyneurophysiologysignal transductiongene sequence analysis

    927

    views

    272

    downloads

    0

    comments

    0

    adaptations

    Chi-Square analysis of two point test cross data
    This flash tutorial simulates analysis of a 2 point test cross and will walk you through the analysis of two hypothetical traits.

    Keywords: geneticssimulationchi-squaredlinkagetest crossrecombinationdemonstrationin-class activityproblem set

    1294

    views

    207

    downloads

    0

    comments

    0

    adaptations

    Open science, open data, open source projects for undergraduate research experiences
    Resource from the 2015 BioQUEST Summer Workshop
    1249

    views

    154

    downloads

    0

    comments

    0

    adaptations

    Targeting Misconceptions in the Central Dogma by Examining Viral Infection
    Understanding the central dogma and how changes in gene expression can impact cell function requires integration of several topics in molecular biology. Students often do not make the necessary...

    Keywords: datatranscriptionvirustranslationprotein functionmembrane transportPredictions

    2828

    views

    440

    downloads

    0

    comments

    0

    adaptations

    An undergraduate bioinformatics curriculum that teaches eukaryotic gene structure
    Gene structure, transcription, translation, and alternative splicing are challenging concepts for many undergraduates studying biology. These topics are typically covered in a traditional lecture...

    Keywords: bioinformaticsGenome BrowsergenomicsRNAseqsplicingComputer ModelGene Structure

    7205

    views

    1383

    downloads

    0

    comments

    0

    adaptations

    2008-Brewer-EtAl-Fitting ordinary differential equations to short time course data
    In this paper, we present a survey of existing algorithms and describe the main approaches. We also introduce and evaluate a new efficient technique for estimating ODEs linear in parameters...

    Keywords: time seriesEvaluation SPLINEgeneleast squaresbifurcation

    84

    views

    36

    downloads

    0

    comments

    0

    adaptations

    A Muscular Dystrophy Case Study Illustrating the Phenotypic Effects of Mutation
    Mutations in genes can lead to a variety of phenotypes, including various human diseases. Students often understand that a particular mutation in a single gene causes a disease phenotype, but it is...

    Keywords: mutationProtein Structureethicscentral dogmahuman disease

    2709

    views

    242

    downloads

    0

    comments

    0

    adaptations

    Studying phylogeny by producing phylogenetic trees of primates using morphological and molecular characteristics.
    An assignment constructing phylogenetic trees using shared, derived morphological traits and molecular differences among 18 primate species and two outlier species has been developed. Skull and...
    664

    views

    136

    downloads

    0

    comments

    0

    adaptations

    Discovering Prokaryotic Gene Regulation by Building and Investigating a Computational Model of the lac Operon
    The ability to construct and reason through a biological system is an important skill to develop in science education. This level of understanding forces students to recognize the interrelatedness...

    Keywords: prokaryotesgene regulationLac Operoninducible operon

    1982

    views

    232

    downloads

    1

    comments

    0

    adaptations

    Splicing it Together: Using Primary Data to Explore RNA Splicing and Gene Expression in Large-Lecture Introductory Biology
    At the heart of scientific ways of knowing is the systematic collection and analysis of data, which is then used to propose an explanation of how the world works. In this two-day module, students...

    Keywords: gene regulationtranscriptiongene expressioncentral dogmarepressoralternative splicingmRNA processingActivatorTranscription factors

    3260

    views

    462

    downloads

    0

    comments

    0

    adaptations

    RNAseq data analysis using Galaxy
    This is a bioinformatics exercise intended for use in a computer lab setting with life science majors.

    Keywords: LabbioinformaticsNCBImappingUndergraduateworkflowNIBLSEGalaxyRNAseqgene expressionAdvancedExtended ProjectArabidopsisC1. Role of bioinformaticsC2. Computational conceptsC3. Statistical conceptsC5. Data retrievalIncubated at NIBLSEdifferentially expressed genes

    1427

    views

    213

    downloads

    0

    comments

    0

    adaptations

    Chapter 9: One-way analysis of variance
    Biostatistics Using R: A Laboratory Manual was created with the goals of providing biological content to lab sessions by using authentic research data and introducing R programming language....

    Keywords: biostatisticsR programming language

    900

    views

    521

    downloads

    0

    comments

    0

    adaptations

    Ethics in Synthetic Biology
    This collection of five activities provide students with an introduction to thinking about ethical concerns in human genome synthesis, gene editing, metabolic engineering, and synthetic genomes.

    Keywords: biostatisticsstatistical analysisavian malariaSummer Workshop 2018

    1006

    views

    218

    downloads

    0

    comments

    0

    adaptations

    Mini-Workshop August 14, 2020
    We reviewed the materials available on Genome Solver (other lessons here) and described our new python pipeline for examining horizontal gene transfer and a new synteny lesson in detail.

    Keywords: Bioinformatics Education

    1166

    views

    1814

    downloads

    0

    comments

    0

    adaptations

    Build-a-Genome Lab Manual for RFP Synthesis
    This lab manual describes a multi-week lab project for the design, assembly from oliognucleotides, cloning, and sequencing of the RFP gene. This resource was developed as part of NSF Award...
    809

    views

    460

    downloads

    0

    comments

    0

    adaptations

    Modeling the lac Operon to Understand the Regulation of Gene Expression in Prokaryotes
    This resource is a recitation activity designed for an introductory biology course in which students explore a lac operon simulation (https://qubeshub.org/resources/phetlacoperon).

    Keywords: simulationLac Operon

    1393

    views

    656

    downloads

    0

    comments

    0

    adaptations

    Web Popgen
    A Hardy-Weinberg simulation program.

    Keywords: Hardy-Weinbergpopulation geneticscomputer simulationsGenetic DriftmutationNatural Selection

    1927

    views

    313

    downloads

    0

    comments

    0

    adaptations

    Close

    Home

    Search