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    Ethics of Gene Editing
    This is an ethical reflection for students on an issue in gene editing. The case study asks students to reflect on material in the two linked articles. Also included is the grading rubric.

    Keywords: biostatisticsstatistical analysisavian malariaSummer Workshop 2018

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    The p53 Gene and Cancer
    This tutorial describes the structure and function of the p53 protein, how its activity is regulated in cells, and how mutant versions of p53 can lead to cancer.

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymolecular biologymacromoleculesGenetic disease

    3293

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    422

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    The Biology of Skin Color
    This film explores the hypothesis that different tones of skin color in humans arose as adaptations to the intensity of ultraviolet radiation in different parts of the world.

    Keywords: Resources @ HHMI - BioInteractivegene regulationgene expressionAnatomy & Physiologyhuman evolutionfilm

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    Hardy-Weinberg Equilibrium
    This module introduces the Hardy-Weinberg model in the context of understanding the population's genotype and allele frequencies. It is intended for an introductory biology audience.

    Keywords: genotypeallelesGenetics and EvolutionFrequenciesHardy-Weinberg model

    902

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    445

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    Population Genetics: Limits to Adaptation
    This module introduces gene flow in the context of understanding the persistence of maladaptive traits in some populations. It is intended for an introductory biology audience.

    Keywords: LogarithmsAlgebraGenetics and Evolution

    820

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    184

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    Using Undergraduate Molecular Biology Labs to Discover Targets of miRNAs in Humans
    In this lesson, we describe an easily adaptable lab module that can be used in existing undergraduate molecular biology lab courses to conduct authentic scientific research, published in CourseSource

    Keywords: molecular biologybioinformaticsNIBLSEgene regulationmicroRNAsgene expressionCourseSourcemiRNA

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    359

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    Introduction to Mathematical Modeling in Biotechnology, Cell Biology, and Physiology
    The course is a mathematical and computational exploration of five diverse areas of biology: human locomotion, gene sequence analysis, signal transduction pathways involved in cancer,...

    Keywords: mathematical modelingcoursehuman locomotionneuroanatomyneurophysiologysignal transductiongene sequence analysis

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    Chi-Square analysis of two point test cross data
    This flash tutorial simulates analysis of a 2 point test cross and will walk you through the analysis of two hypothetical traits.

    Keywords: geneticssimulationchi-squaredlinkagetest crossrecombinationdemonstrationin-class activityproblem set

    1342

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    217

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    Open science, open data, open source projects for undergraduate research experiences
    Resource from the 2015 BioQUEST Summer Workshop
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    2003-Yildirim-Mackey-Feedback Regulation in the Lactose Operon
    A mathematical model for the regulation of induction in the lac operon in Escherichia coli is presented.

    Keywords: mRNAlactoselactose operonfeedback regulation

    169

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    2008-Brewer-EtAl-Fitting ordinary differential equations to short time course data
    In this paper, we present a survey of existing algorithms and describe the main approaches. We also introduce and evaluate a new efficient technique for estimating ODEs linear in parameters...

    Keywords: time seriesEvaluation SPLINEgeneleast squaresbifurcation

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    0

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    Studying phylogeny by producing phylogenetic trees of primates using morphological and molecular characteristics.
    An assignment constructing phylogenetic trees using shared, derived morphological traits and molecular differences among 18 primate species and two outlier species has been developed. Skull and...
    700

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    143

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    The Three Sisters of Agriculture: An Active Learning Activity on Symbiotic Nitrogen Fixation
    This active learning exercise introduces students to the plant microbiome and the contributions that bacteria make to plant growth and food production. The Three Sisters are an ancient indigenous...

    Keywords: SymbiosisPlant microbiomeNitrogen fixationNutritional content of foodElectron flowSociety impact of microorganisms

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    175

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    RNAseq data analysis using Galaxy
    This is a bioinformatics exercise intended for use in a computer lab setting with life science majors.

    Keywords: LabbioinformaticsNCBImappingUndergraduateworkflowNIBLSEGalaxyRNAseqgene expressionAdvancedExtended ProjectArabidopsisC1. Role of bioinformaticsC2. Computational conceptsC3. Statistical conceptsC5. Data retrievalIncubated at NIBLSEdifferentially expressed genes

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    Chapter 9: One-way analysis of variance
    Biostatistics Using R: A Laboratory Manual was created with the goals of providing biological content to lab sessions by using authentic research data and introducing R programming language....

    Keywords: biostatisticsR programming language

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    Ethics in Synthetic Biology
    This collection of five activities provide students with an introduction to thinking about ethical concerns in human genome synthesis, gene editing, metabolic engineering, and synthetic genomes.

    Keywords: biostatisticsstatistical analysisavian malariaSummer Workshop 2018

    1053

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    Mini-Workshop August 14, 2020
    We reviewed the materials available on Genome Solver (other lessons here) and described our new python pipeline for examining horizontal gene transfer and a new synteny lesson in detail.

    Keywords: Bioinformatics Education

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    Build-a-Genome Lab Manual for RFP Synthesis
    This lab manual describes a multi-week lab project for the design, assembly from oliognucleotides, cloning, and sequencing of the RFP gene. This resource was developed as part of NSF Award...
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    Modeling the lac Operon to Understand the Regulation of Gene Expression in Prokaryotes
    This resource is a recitation activity designed for an introductory biology course in which students explore a lac operon simulation (https://qubeshub.org/resources/phetlacoperon).

    Keywords: simulationLac Operon

    1449

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    686

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    Web Popgen
    A Hardy-Weinberg simulation program.

    Keywords: Hardy-Weinbergpopulation geneticscomputer simulationsGenetic DriftmutationNatural Selection

    1989

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    327

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