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    1987-Claude-Marmasse-Studies on differential equations of enzyme kinetics-Biomolecular scheme
    The integral curve is compared with the solutions given by the two classical approximations to the problem: it is shown that the steady-state approximation is to be preferred to the rapid...

    Keywords: steady-state modelisoclinesenzyme kinetics

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    1-034-T-FishMixing-ModelingScenario
    This activity gives students a chance to build the underlying differential equation and/or difference equation for a mixing problem using tangible objects (fish) and a student-designed restocking...

    Keywords: simulationfishFishingmixingrestocking

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    1-021-FeralCatControl-ModelingScenario
    Students act as professional mathematical consultants and write a report analyzing the client's problem. The client company is a fictional organization which advocates for the use of...

    Keywords: population growthcontrolferal catspopulation controlneutertrap-killtrap-neuter-return

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    1-138-InnerEarDrugDelivery-ModelingScenario
    Students examine local drug delivery to the cochlea. The delivery system is modeled as a liquid mixing problem. Students formulate the differential equation, and solve the equation using separation...

    Keywords: concentrationdrug deliveryinner earcochleahearing loss

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    3-026-SpringInverseProblem-ModelingScenario
    We are given data on the position of a mass in an oscillating spring mass system and we seek to discover approaches to estimating an unknown parameter.

    Keywords: datamassinverse problemspring\parameter estimate

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    1-016-DogDrugs-ModelingScenario
    We offer a problem to determine the necessary drug administration in order to keep a dog sedated with specific information on half-life for an exponentially decaying presence of the drug in the body.

    Keywords: wild_dogsdrug discoveryhalf-lifepentobarbital sodiumanesthesia

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    Mystery box puzzle for model based reasoning
    This is a computer based problem solving activity that I use to engage introductory biology students with discussions about model based reasoning.

    Keywords: Model Based ReasoningScientific reasoningpuzzle

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    21st Century STEM Workforce Skills
    This activity includes a leadership assessment and associated exercise to encourage the development of 21st Century STEM Skills.

    Keywords: collaborationteam scienceleadership skills

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    Search for the Missing Sea Otters
    National Center for Case Study Teaching in Science- using a progressive disclosure format, this case study teaches students how to apply ecological principles to a real-life ecological problem.

    Keywords: Community Ecologypopulation ecologypredationAlaskaSea otterkiller whaleOrcinus orcamarine mammalkelp bedpredatorecological energetics

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    Exploring HIV Evolution
    In this activity you will study aspects of sequence evolution by working with a set of HIV sequence data from 15 different subjects (Markham, et al., 1998). You will first learn about the dataset,...

    Keywords: EvolutionbioinformaticssequencingUndergraduateNIBLSEincubatorsHIVAudience LevelC1. Role of bioinformaticsC4. Bioinformatics toolsRecommended by NIBLSE

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    2012-Transtrum-Qiu-Optimal experiment selection for parameter estimation in biological differential equation models
    We explore the question to what extent parameters can be efficiently estimated by appropriate experimental selection.

    Keywords: experimental designsystems biologyAssociation & Data Fittingreaction ratesdecay rates

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    2012-Nokkaew-EtAl-Estimation of Algae Growth Model Parameters by a Double Layer Genetic Algorithm
    This paper presents a double layer genetic algorithm (DLGA) to improve performance of the information-constrained parameter estimations.

    Keywords: optimizationalgae growthgenetic algorithmssimulated dataconvergence of parameters

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    1972-Suresh_Sethi-Optimal Control of the Vidale-Wolfe Advertising Model
    This paper considers an optimal-control problem for the dynamics of the Vidale-Wolfe advertising model, the optimal control being the rate of advertising expenditure to achieve a terminal market...

    Keywords: Optimal Control Theoryadvertisingsales

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    3-061-ChemEngApps-ModelingScenario
    Students go through a chemical engineering problem: calculate concentration profile of cyclohexane within a catalyst pellet by solving a second order linear differential equation; then analyze the...

    Keywords: Spanishporous mediumcatalyisiscyclohexenehydrogeldehydrogenationhyperbolic trig functions

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    9-015-UnearthingTruth-ModelingScenario
    This project introduces \textit{electrical resistivity tomography}, a technique of interest for geophysical imaging, used to produce images of underground features or structures by using electrical...

    Keywords: geophysicalImagingStatistical inverse problemtunnelconductionHolocaustVilniusDivergence TheoremfluxLaplace's equationimpedanceelectrical resistivity tomographytomographyresistivity

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    Necessary and Sufficient? Solving the Mystery of the Mitochondrial Pyruvate Transporter
    While there are several available lessons for teaching introductory biology students about diffusion, facilitated diffusion, and active transport, fewer materials exist to support upper-division...

    Keywords: DiffusionActive transportfacilitated diffusionNecessary and sufficientTransport proteins

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    Investigating the Function of a Transport Protein: Where is ABCB6 Located in Human Cells?
    One of the challenges of teaching Cell Biology is helping students understand important research methods used to study cells.  The goal of understanding cell biology methods is especially...

    Keywords: ABC transporter familyDifferential centrifugationImmunoblottingImmunofluorescence assayProtein localizationPurifying organellesSDS-PAGE

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    Good Drug, Bad Practice: Tackling the Ivermectin Fiasco
    Throughout history, biomedical advancements have alleviated suffering worldwide and significantly advanced human well-being. As researchers and educators, we are well-familiar with the...

    Keywords: Peer reviewCOVID19fraudtherapeutic drugIvermectin

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    2008-Duran-Caginalp-Parameter optimization for differential equations in asset price forecasting
    The optimization procedure is used in conjunction with daily market prices (MPs) and net asset values to determine the parameters for which the AFDE yield the best fit for the previous n days.

    Keywords: financeinverse problemnumerical nonlinear optimizationasset flowfinancial market dynamicsmarket return prediction algorithm

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    Rivers as Social-Ecological-Technological Systems: Integrative Issue Formulation and Problem Solving
    Flowing surface waters continue to capture the human imagination and are increasingly harnessed by many interdependent human activities. Existing theories for studying rivers as cohesive ecological...

    Keywords: Interdisciplinary STEMProblem based learningcomplex systemsexperiential learningRiver Field Studies Network

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