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    Exploring the evolution of caffeine biosynthesis enzymes
    Caffeine is a very common stimulant consume worldwide as tea, coffee, mate, cocoa, and chocolate. Ever wondered why plants make caffeine? Do all caffeine producing plants have the same enzymes for...

    Keywords: Bioinformatics EducationBioinformatics and Genomics

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    Amylase Copy Number and Diet
    An adapted module from HHMI Spreadsheet Tutorials using amylase data for students to gain data analysis and excel skills

    Keywords: Scientific ProcessStatistics and MathScientific Methodology

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    Using genome browsers constructed by G-OnRamp to provide students with a Course-based Undergraduate Research Experience in genome annotation
    G-OnRamp (http://g-onramp.org) provides an easy-to-use web platform for educators to create genome browsers to engage undergraduate students in research projects, both collaborative annotation of...
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    Lesson II - Databases
    Genome Solver began as a way to teach undergraduate faculty some basic skills in bioinformatics; no coding or scripting is required. Lesson II introduces the principal databases for microbial...

    Keywords: Bioinformatics EducationBioinformatics and Genomics

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    Examining the Physiology Behind the Symptoms of Lactose Intolerance
    This is a set of extension questions for the HHMI short film The Making of the Fittest: Got Lactase? The Co-evolution of Genes Video Activity.
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    Module 6: Alternative Splicing
    This module explores how multiple different mRNAs and polypeptides can be encoded by the same gene. After completing this module students will be able to explain how alternative splicing of a gene...

    Keywords: geneticsdata visualizationmolecular biologygenomicsexonintronalternative splicingSimilarity searchesMessenger RNA

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    HHMI SEA-PHAGES and GENES: Course-based UREs Designed for All
    The HHMI Science Education Alliance (SEA) program supports a community of faculty members and institutions embed research as a fundamental component of early undergraduate science curricula.

    Keywords: course-based research experiences (CUREs)SEA-PHAGES

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    Lesson IV - Comparative Genomics
    Genome Solver began as a way to teach undergraduate faculty some basic skills in bioinformatics; no coding or scripting is required. Lesson IV, Comparative Genomics, discusses some of the tools...

    Keywords: Bioinformatics EducationBioinformatics and Genomics

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    DNA Subway Learning Resources
    DNA Subway is a NIBLSE Recommended resource. This is a collection of learning resources associated with DNA Subway.

    Keywords: phylogeneticsIntroductoryLabbioinformaticsUndergraduateNIBLSEDNA BarcodingDNA sequenceBLASTmultiple sequence alignmentDNA SubwayInstructional SettingAudience LevelAdvancedActivity LengthExtended ProjectC1. Role of bioinformaticsC2. Computational conceptsC4. Bioinformatics toolsC5. Data retrievalC8. Data types

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    Lesson VI - The Community Science Project
    Genome Solver's Community Science Project was developed as a way to use the skills taught in the previous lessons. We're asking members of the community to provide instances of potential phage...

    Keywords: Bioinformatics EducationBioinformatics and Genomics

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    GEA Introductory lesson on BLAST
    The "Introduction to BLAST using Human Leptin" exercise aims to introduce students to the use of the Basic Local Alignment Search Tool (BLAST) to identify related sequences and compare similarity...

    Keywords: geneticsProbabilitydatabasebioinformaticsphylogenetic analysisgenomicsBLASTProtein sequenceSimilarity searches

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    Regulación de expresión génica y adipogénesis por PPAR-γ
    En ésta actividad de dibujo / coloreado los estudiantes aprenderán sobre los diferentes componentes involucrados en la regulación de la activación de PPAR-γ, un factor de transcripción que juega un...

    Keywords: videosResources @ HHMI - BioInteractiveGeneral biology educationgene expressionregulationtranslation into spanishtranscriptional regulationrepressorEspañol

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    Using Raw Sequence Data to Analyze Tumor Suppressor Mutations
    Learning to identify DNA sequence variants from raw sequencing data (electropherograms) is a basic molecular biology skill with applications to basic research and clinical practice. Yet learning to...

    Keywords: bioinformaticsmutationDNAgenomic visualizationparts of a geneclinical consequencesraw data

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    Why do Some People Inherit a Predisposition to Cancer? A small group activity on cancer genetics
    Before undergraduate students take a genetics course they generally know cancer has a genetic basis and involves the proliferation of cells; however, many are uncertain about why only a subset of...

    Keywords: cancerInheritance patternsProbability calculationProto-oncogeneTumor Suppressor Gene

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    Honoring the Complexity of Genetics: Exploring the Role of Genes and the Environment Using Real World Examples
    Historically, undergraduate genetics courses have disproportionately focused on the impact of genes on phenotypes, rather than multifactorial concepts which consider how a combination of genes, the...

    Keywords: genesenvironmentMendelQuantitative traitsMultifactorialGene by environment interactions

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    Learn genomics and bioinformatics through scientific thinking, creation and analysis (virtual and hands-on)
    Nucleic acid are biological molecules composed of nitrogen-containing bases, phosphate groups, and sugar molecules. The complimentary chemical bonding results in formation of double stranded DNA....

    Keywords: data analysisbioinformaticsnucleotidesproteinsRNAgenomicsScientific communicationscientific writingDNAmodelling scientific thinkinggenescientific thinkingcreation

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    Teaching Protein Structure Modeling
    New strains of microbes have been regularly discovered and brought into a laboratory for study in many different directions. When a new microbial genome is sequenced and assembled, the homologues...

    Keywords: Microbiology Educationbioinformaticsprotein structure modeling

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    Using Bioinformatics to Understand Genetic Diseases: A Practical Guide
    This Practical Guide outlines a number of basic bioinformatics approaches that can be used to understand the molecular basis of genetic diseases.
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    Louse Genetics, Genomics, and Gene Function...Oh My!
    In this module, students will be investigating a louse gene with an unknown function to determine if it might be important in the evolution of the louse ecomorphs.

    Keywords: parasitesgenomicsgene sequence analysisFunctional Genomics

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    Birds and Lice: Reciprocal Natural Selection
    This exercise investigates the form and function of lice and their relationship to their bird host.

    Keywords: BiodiversityparasitesbirdsCoevolutionnatural history collections

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