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    Going Remote: An Online Adaptation to Using a Primary Cell Culture Model to Study the Neural Extracellular Matrix
    In light of the COVID-19 pandemic, instructors have modified materials to transition to a remote learning platform. The challenge for science instructors has been to design lab exercises that...

    Keywords: remote learningExtracellular matrixNeural extracellular matrixPerineuronal net

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    Using Open-Source Bioinformatics and Visualization Tools to Explore the Structure and Function of SARS-CoV-2 Spike Protein
    The relationship between protein structure and function is a foundational concept in undergraduate biochemistry. We find this theme is best presented with assignments that encourage exploration and...

    Keywords: bioinformaticsmolecular modelingCOVID19protein structure and functionUCSF ChimeraSARS-CoV-2 spike proteinACE2 receptor

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    A Short Laboratory Module to Help Infuse Metacognition during an Introductory Course-based Research Experience
    A core competency identified in Vision and Change for undergraduate biology students is the Ability to Apply the Process of Science. Here, we describe a three-week laboratory module for students in...

    Keywords: metacognitiongene expressionScientific ProcessExperimenal DesignHypothesis Generationmodel organisms

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    Evaluating the Quick Fix: Weight Loss Drugs and Cellular Respiration
    One key to student success in introductory and cell biology courses is a foundational knowledge of cellular respiration. This is a content area in which students often harbor misconceptions that...

    Keywords: data analysisCellular RespirationElectron Transport ChainEnergy transformationsMitochondriaOxidative phosphorylationWeight loss drugs24-dinitrophenol (DNP)

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    Translating Co-Translational Translocation
    Understanding the process of proteins targeting to specific locations within a cell is a fundamental part of cell biology. Synthesis of proteins by co-translational translocation, which also...

    Keywords: Topologyco-translational translocationendoplasmic reticulumprotease protection assaysecretory proteinssignal sequencetransmembrane proteins

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    Quantifying Bacterial Growth in the Guts and Hemolymph of Fruit Flies: Mathematical Modeling and Data Interpolation/Extrapolation
    In this activity, students will analyze raw data obtained from an experiment that explores the effect of overexpressing the Ssk protein in order to strengthen the intestinal barrier and prevent...

    Keywords: graphingexponential growthlinear modelsqbccinterpolationConcepts in Statistics and Precalculus Understanding exponential rates and linear slopesExtrapolation

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    Garden Variety Mutations: Using Primary Data to Understand the Central Dogma in Large-Lecture Introductory Biology
    The ability to interpret and create an argument from data is a crucial skill for budding scientists, yet one that is seldom practiced in introductory courses. During this argumentation module,...

    Keywords: mutationtranscriptiongene expressioncentral dogmatranslationgel electrophoresisGenotype/Phenotype

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    Collaborative case writing and field testing with Molecular CaseNet brings together discipline specific expertise for innovative pedagogical tools in the classroom
    Molecular case studies (MCS) use an interesting story as a hook , followed by exploration of biochemistry of one or more molecules of interest.  They can be useful in teaching about macromolecule...
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    1-046-GoingViral-ModelingScenario
    Students participate in a simulation of the spread of a viral disease in the classroom and model the process with a logistic differential equation. The simulation uses random numbers and the entire...

    Keywords: simulationmathematical modeldatalogisticrandom number generatorfittingrandom process

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    Assessing Socioeconomic Trends in Tree Cover and Human Health in Urban Environments
    In this exercise, students use a combination of publicly available data and tree cover data that they generate using iTree Canopy to test whether tree cover is equitably distributed within the city...

    Keywords: social justiceSimple Linear Regressionenvironmental justiceGeographic Information System (GIS)Using ExcelConnection to PlaceredliningEcosystem Servicesurban tree coverurban environments

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    STEM Inclusive Teaching Practices Webinar Series: Episode One
    Episode One is a conversation with Bryan Dewsbury (University of Rhode Island) one of the authors of the CBE-LSE Inclusive Pedagogy guide.

    Keywords: idigbioundergraduate educationwebinarInclusive teachingEDSINBLUE

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    Geoscience Methods and Resources for K-5 Pre-Education Majors
    : Exploring Geoscience Methods was an excellent capstone experience for Elementary Education Majors. The class I used this module with was 24 students of various backgrounds and academic...

    Keywords: geneticsvideosQUBESecologyResources @ HHMI - BioInteractiveMathematical Biologycalculusjavaorganismal biologyquantitative biologybioinformaticsneurosciencegenomicscancerSecondaryyoutubemicrobiomeFaculty Mentoring NetworksalamanderCapture mark-recaptureAudience level - Introductory UG - majorsAudience level - Introductory UG - non-majorsecosystemsgenetic basis of diseasebiology of cellshuman reproductionfood chainIntroduction to Modelingrandom number generatorPost-secondaryLower DivisionPossible TasksModeling ProjectBuildCompareEvaluateexponential decayrecursionabsorptionelimination

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    Osmosis: Determination of the rate of osmosis and the isotonic concentration
    This module contains exercises designed to help students understand how solute concentrations affect the direction and rate of osmosis. Students are given different scenarios to predict the...

    Keywords: introductory biologyQuantitative reasoninginterdisciplinarycell functionOsmosisNIQBC2. Data and GraphsC4. mathematical modelsC6. Quantitative LanguageC1. NumeracyC5. Logic and Algorithms

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    2017-Bonin-EtAl-Mathematical modeling based on ordinary differential equations - promising approach to vaccinology
    As a proof of concept, we developed a model of the immune response to vaccination against the yellow fever. Our simulations have shown consistent results when compared with experimental data...

    Keywords: immune systemyellow fevercomputational immunologycomputational vaccinology

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    2016-Bonin-EtAl-Mathematical modeling based on ordinary differential equations-vaccinology
    We developed a model of the immune response to vaccination against the yellow fever. Our simulations have shown consistent results when compared with experimental data available in the literature.

    Keywords: Immunologyimmune systemAntigenvaccinologyyellow fever

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    HITS: A network to create inquiry-based case studies that make high-throughput approaches and discovery accessible
    Poster on the work of the NSF-funded High-throughput Discovery Science & Inquiry-based Case Studies for Today’s Students (HITS) Research Coordination Network. Presented at the 2021 BIOME Institute.

    Keywords: case studieshigh-throughputHITSHigh-throughput Discovery Science & Inquiry-based Case Studies for Today’s Students2021 BIOME

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    Waking up Anna - Adaptations and Conversion to Mol*
    This case focuses on understanding the molecular basis of Anna's sleeping disorder and its treatment. The adaptations addressed question clarity and reformatting to use Mol*.

    Keywords: sleepmolecular visualization and analysisPDBMolecular Case StudyGABAMolCaseNetMol*MolStarProtein visualizationFlumazenil

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    Waking up Anna
    This case focuses on understanding the molecular basis of Anna's sleeping disorder and its treatment.

    Keywords: sleepmolecular visualization and analysisPDBMolecular Case StudyGABA

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    Serenity now! Keep calm and do science with real data in the classroom
    Presentation on a free web application currently under development on QUBES called Serenity at the 5th Life Discovery Conference

    Keywords: data sciencetool:serenity5th Life Discovery- Doing Science Education conference (LDC)5th Life Discovery Conference

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    Serenity now! Keep calm and do science with real data in the classroom
    Session presented at NABT 2018 in San Diego, CA

    Keywords: NABTdata scienceeducational technologytool:serenitydata acumendata life cycle

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