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The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

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    Sequence Similarity: A Quick Introduction to Bioconductor
    Following the Sequence Similarity exercises by Kleinschmit, et al., this tutorial will guide students in using the Bioconductor suite of R packages to likewise compute sequence similarity.

    Keywords: bioinformaticssequencingNIBLSEmultiple sequence alignmentsequence similarityBLOSUM scoring matrixBioconductor

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    Setting Up Nonparametric Tests
    This swirl lesson will show you how to rearrange your data within R from one that shows a multiple factor design (2 x 2) to a single factor (4 levels) to allow for data analyses that require...
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    Ethics of Metabolic engineering
    This is an ethical reflection for students on an issue in metabolic engineering and the potential for "home-brew" morphine. The case study asks students to reflect on material in the linked...

    Keywords: biostatisticsstatistical analysisavian malariaSummer Workshop 2018

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    Ethics in synthetic genomics
    This is an ethical reflection for students on an issue in genome engineering and the synthesis of potentially infectious viruses. The case study asks students to reflect on material in the linked...

    Keywords: biostatisticsstatistical analysisavian malariaSummer Workshop 2018

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    Ethics of Gene Editing
    This is an ethical reflection for students on an issue in gene editing. The case study asks students to reflect on material in the two linked articles. Also included is the grading rubric.

    Keywords: biostatisticsstatistical analysisavian malariaSummer Workshop 2018

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    Biobyte 4 - The role of data science principles and practices in undergraduate biology
    This short activity was an effort to launch a community conversation around the interface of data science principles and practices and undergraduate biology education. A variety of resources,...

    Keywords: biostatisticsstatistical analysisavian malariaSummer Workshop 2018

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    Summer 2019 Biobytes
    This series includes the four Biobytes that were piloted at the 2019 BioQUEST / QUBES Summer Workshop titled, “Evolution of Data in the Classroom: From Data to Data Science”.

    Keywords: biostatisticsstatistical analysisavian malariaSummer Workshop 2018

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    Finding Selection in All the Right Places
    Lab introducing students to evolutionary genetics using bioinformatics and biocuration, published as GSA Learning Resource

    Keywords: geneticsbioinformaticssequencingNIBLSE

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    A Very Basic Tutorial for Performing Linear Mixed Effects Analyses: Tutorial 2
    The second of two tutorials that introduce you to linear and linear mixed models. This tutorial serves as a quick boot camp to jump-start your own analyses with linear mixed effects models.

    Keywords: statisticsRdata analysisgraphingconceptsstatsregressionmixed modelslinear modelsfixed effectsrandom effectsintroductionResources @ QUBES - Teaching & Referencetechnologytutorial 2boot campbeginner

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    Linear Regression (Excel) and Cellular Respiration for Biology, Chemistry and Mathematics
    Students typically find linear regression analysis of data sets in a biology classroom challenging. These activities could be used in a Biology, Chemistry, Mathematics, or Statistics course. The...

    Keywords: statisticsmathematicsdata analysisdatalinear regressionbiologyonlinegraphinglinear equationsQuantitative reasoningassessmentcollege algebracellstatistical analysisregressionOERAlgebrachemistryModelscorrelationSimple Linear RegressionMicrosoft Excellab activityexperimentCellular ProcessesATPqbccUsing Excelmanipulate equationsCellular and Molecular BiologyConcepts in Statisticsoxidationline of best fitexplaining statisticsusing statisticsCellular RespirationPredictionsRespirationgraphing in ExcelLinear CorrelationExothermic Reactioncreate scatter plotAdenosine Triphosphate (ATP)germinating peasPre-lab activityStudent activityHybridCollecting DataR-squareRegression ModelFunctionDependent VariablesIndependent VariablesLinear EquationLinear Equation in two variablescreate graphcreate equationcreate regressioncreate plotinterpret regressioninterpret data

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    Quantifying Bacterial Growth in the Guts and Hemolymph of Fruit Flies: Mathematical Modeling and Data Interpolation/Extrapolation
    In this activity, students will analyze raw data obtained from an experiment that explores the effect of overexpressing the Ssk protein in order to strengthen the intestinal barrier and prevent...

    Keywords: graphingexponential growthlinear modelsqbccinterpolationConcepts in Statistics and Precalculus Understanding exponential rates and linear slopesExtrapolation

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    2017-Rosario-Antony-Mathematical Model for Future Population Scenario In India And China – An Econometric Approach
    A mathematical model including dynamical systems, statistical models and differential equations involves variety abstract structures. Population growth is one of the main issues in India and China...

    Keywords: logisticIndiavital coefficientsAsiaCarrying Vapacitiyannual growth rate

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    2009-Su-EtAl-Fitting Compartmental Models to Multiple Dose Pharmacokinetic Data using SAS
    In the case of a multiple dose study where subjects experience different dosing times, a superposition principle can be used to recursively account for each additional dose.

    Keywords: SASsuperpositionpharmacokineticscompartmental modelsmultiple dose

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    1975-Rodda-Sampson-Smith-The One-Compartment Open Model Parameter Estimation
    A new estimation procedure is proposed for estimating the parameters of the simplest pharmacokinetic model, the one-compartment open model.

    Keywords: compartment modelpharmacokineticsnonlinear estimationone compartment model

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    Theory, models and biology
    Theoretical ideas have a rich history in many areas of biology, and new theories and mathematical models have much to offer in the future.

    Keywords: researchmathematical modelingtheoretical biologyResources @ QUBES - Teaching & Reference

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    Effect of the Intestinal Protein Snakeskin on the Lifespan of Fruit Flies: A Kaplan-Meier Survival Analysissource Draft (1)
    In this activity, students perform the Kaplan-Meier survival analysis on raw data obtained from an experiment that explores the effect of overexpressing the Snakeskin (Ssk) protein on the lifespan...

    Keywords: graphingBiochemistryhypothesis testingcalculus and biologyapproximating areas under curvesqbccCellular and Molecular BiologyCreate graphsInterpret graphsSolving Equations and Inequalitiesinterpret tablesConcepts in Statisticsusing statisticschi-square analysissurvival analysis

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    2007-Ramsay-Hooker-Campbell-Cao-Parameter estimation for differential equations-a generalized smoothing approach
    We propose a new method for estimating parameters in models that are defined by a system of non-linear differential equations.

    Keywords: estimating equationfunctional data analysisGauss–Newton methodparameter cascadeprofiled estimationdynamic system

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    6-001-Epidemic-ModelingScenario
    This paper presents real-world data, a problem statement, and discussion of a common approach to modeling that data, including student responses. In particular, we provide time-series data on the...

    Keywords: datadifference equationsparameter estimationcontinuousepidemicdiscreteboarding school

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    Remote Sensing of Plants and Topography in R (Project EDDIE) for Advanced GIS class
    Students will explore different possible abiotic drivers of plant growth, defined as greenness and height. In the final step, students will analyze data from around the United States and consider...
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    Assessing River Herring Migration Using Nonparametric Analysis
    In this lesson, users will play the role of a fisheries biologist by tackling a contemporary fisheries research problem by performing data normality tests, data transformations, nonparametric...

    Keywords: testR Markdownfisheries scienceanadromouschesapeake bayriver herringfisheries managementelectronic fish counterblueback herringalewifevirginiachickahominyriverwalker's damnonparametricwilcoxonsignedranknormalityfish migration

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