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  1. Learn genomics and bioinformatics through scientific thinking, creation and analysis (virtual and hands-on)

    11 Jun 2024 | Teaching Materials | Contributor(s):

    By Dr Pankaj Mehrotra

    University of the People, California, United States of America

    Nucleic acid are biological molecules composed of nitrogen-containing bases, phosphate groups, and sugar molecules. The complimentary chemical bonding results in formation of double stranded DNA....

    https://qubeshub.org/publications/4852/?v=1

  2. Using Raw Sequence Data to Analyze Tumor Suppressor Mutations

    05 Jun 2024 | Teaching Materials | Contributor(s):

    By James D. Fackenthal*

    Benedictine University

    Learning to identify DNA sequence variants from raw sequencing data (electropherograms) is a basic molecular biology skill with applications to basic research and clinical practice. Yet learning to...

    https://qubeshub.org/publications/4704/?v=1

  3. An Interactive Protocol for In-Classroom DNA Extraction

    22 Sep 2023 | Teaching Materials | Contributor(s):

    By Danica C. Levesque1, Athena L. Wallis1, Jenna Daypuk1, Jesse Petahtegoose1, Mitchell Slobodian1, Allie K. Sutherland-Hutchings1, Ian Black1, Jessica M. Vélez2, Abdullah Abood3, Marah H. Wahbeh4, Romina B. Cejas5, Angel F. Cisneros6, Laerie McNeil1, Kento Konno1, Lissa McGregor1, Birha Farooqi1, Carla Bautista6, Subhash Rajpurohit7, Divita Garg7, Jiechun Zhu1, Guangdong Yang1, Solomon Arthur1, Thomas J. S. Merritt*8

    1. Laurentian University 2. Genetics Society of America 3. University of Virginia 4. Johns Hopkins University School of Medicine 5. University of Buffalo 6. Université Laval 7. Ahmedabad University 8. Laurentian Univeristy

    Using commonly available materials, this tool allows students to extract DNA, exploring DNA chemistry and the principles of experimental design and execution. We take a “Choose Your Own...

    https://qubeshub.org/publications/4518/?v=1

  4. Sanger Sequencing by Hand: Using Paper Clips to Demonstrate Chain Termination

    20 Feb 2023 | Teaching Materials | Contributor(s):

    By Caroline E. Smith*1, Chrystal Ho Pao1

    Trinity International University

    Sanger sequencing is commonly taught with a hands-on approach. Sanger sequencing involves chain termination by dideoxynucleotides, because they are missing the oxygen on the 3’ carbon atom,...

    https://qubeshub.org/publications/3654/?v=1

  5. Hands-On, Hands-Off: The Community College Genomics (ComGen) Course-Based Undergraduate Research Experience

    10 Oct 2022 | Teaching Materials | Contributor(s):

    By Gita Bangera*1, Kimberly Harrington2, Irene Shaver3

    1. Bellevue College 2. Tacoma Community College 3. Belleveue College

    Science is a process of discovery where failure is inherent and iteration is necessary, yet instructors often teach the scientific process as if it is a controlled, highly supervised, confirmatory...

    https://qubeshub.org/publications/3529/?v=1

  6. A "Box of Lessons" for Exploring Biomolecular Structure and Function

    20 Jul 2022 | Teaching Materials | Contributor(s):

    By Keith A. Johnson1, Alexandra Pettit2, Sheela Vemu3, Shuchismita Dutta4

    1. Bradley University College of Liberal Arts and Sciences 2. Carleton University 3. Waubonsee Community College - 4. RCSB Protein Data Bank, Rutgers University

    Biomolecular structure and function is emphasized as a core concept in a variety of community determined educational standards for biology and chemistry. Most curricula introduce students to the...

    https://qubeshub.org/publications/3448/?v=1

  7. A Curious Display

    05 Nov 2021 | Teaching Materials | Contributor(s):

    By Margaret Waterman1, Brandon Call, Sandi Connelly2, Kristin Jenkins3, Sam Catherine Johnston4, Vedham Karpakakunjaram5, Viet Le6, Hayley Orndorf7, Melissa Skyer8, Barbara Spiecker9

    1. Southeast Missouri State University 2. Rochester Institute Of Technology 3. BioQUEST 4. CAST Inc. 5. Montgomery College 6. Rochester Institute of Technology 7. University of Pittsburgh 8. National Technical Institute for the Deaf at Rochester Institute of Technology 9. Oregon State University

    Case study on genetically modified organisms provided in English and American Sign Language.

    https://qubeshub.org/publications/1452/?v=2

  8. DNA Detective: Genotype to Phenotype. A Bioinformatics Workshop for Middle School to College.

    29 Aug 2021 | Teaching Materials | Contributor(s):

    By Anne L. Sternberger*1, Sarah E. Wyatt1

    Ohio University

    Advances in high-throughput techniques have resulted in a rising demand for scientists with basic bioinformatics skills as well as workshops and curricula that teach students bioinformatics...

    https://qubeshub.org/publications/2652/?v=1

  9. CURE-all: Large Scale Implementation of Authentic DNA Barcoding Research into First-Year Biology Curriculum

    28 Aug 2021 | Teaching Materials | Contributor(s):

    By Oliver Hyman*1, Elizabeth Doyle1, Joseph Harsh1, Joanna Mott2, Andrea Pesce1, Bejan Rasoul1, Kyle Seifert1, Ray Enke1

    1. James Madison University 2. California State University

    Growing calls in science education reform have emphasized wide-scale engagement of first-year undergraduate students in authentic research experiences; however, large course enrollments, inadequate...

    https://qubeshub.org/publications/2625/?v=1

  10. The Case of the Missing Strawberries: RFLP analysis

    20 Aug 2021 | Teaching Materials | Contributor(s):

    By Heidi Major Sleister

    Drake University

    While solving the fictional mystery of the missing strawberries, students are engaged in a guided-inquiry lesson featuring small-group and class discussions, hands-on activities, and laboratory...

    https://qubeshub.org/publications/2524/?v=1

  11. The Ames Test

    08 Jan 2021 | Teaching Materials | Contributor(s):

    By Nathan Goodson-Gregg, Elizabeth A. De Stasio

    Introduction to the Ames Test, published as GSA Learning Resource

    https://qubeshub.org/publications/987/?v=2

  12. Building creatures with the central dogma of biology

    02 Dec 2019 | Teaching Materials | Contributor(s):

    By Melissa Skyer

    National Technical Institute for the Deaf at Rochester Institute of Technology

    Activity that demonstrates how nucleotide changes can affect phenotypes

    https://qubeshub.org/publications/1445/?v=1

  13. A Curious Display

    28 Oct 2019 | Teaching Materials | Contributor(s):

    By Margaret Waterman1, Brandon Call, Sandi Connelly2, Kristin Jenkins3, Sam Catherine Johnston4, Vedham Karpakakunjaram5, Viet Le6, Hayley Orndorf7, Melissa Skyer8, Barbara Spiecker9

    1. Southeast Missouri State University 2. Rochester Institute Of Technology 3. BioQUEST 4. CAST Inc. 5. Montgomery College 6. Rochester Institute of Technology 7. University of Pittsburgh 8. National Technical Institute for the Deaf at Rochester Institute of Technology 9. Oregon State University

    Case study on genetically modified organisms

    https://qubeshub.org/publications/1452/?v=1

  14. Gelin’: Gel Electrophoresis Simulation

    24 Oct 2019 | Teaching Materials | Contributor(s):

    By Beyond Benign

    Students will understand how DNA is separated into a fingerprint by using a chromatography activity to simulate gel electrophoresis.

    https://qubeshub.org/publications/1448/?v=1

  15. DNA and Knot Theory

    15 Feb 2019 | Teaching Materials | Contributor(s):

    By Lou Gross1, Monica Beals1, Susan Harrell1

    University of Tennessee Knoxville

    This module introduces knot theory in the context of understanding the packing of DNA. It is intended for an introductory biology audience.

    https://qubeshub.org/publications/1047/?v=1

  16. Using computational molecular modeling software to demonstrate how DNA mutations cause phenotypes

    04 Jan 2019 | Teaching Materials | Contributor(s):

    By Tara Phelps-Durr

    Radford University

    This lesson is a five-week series of laboratory activities designed to help students transition from applying lower order thinking skills to the central dogma to applying higher-order thinking skills.

    https://qubeshub.org/publications/1006/?v=1

  17. Bioinformatics: An Interactive Introduction to NCBI

    03 Jan 2019 | Teaching Materials | Contributor(s):

    By Seth Bordenstein

    Marine Biological Laboratory

    Modules showing how the NCBI database classifies and organizes information on DNA sequences, evolutionary relationships, and scientific publications. And a module working to identify a nucleotide...

    https://qubeshub.org/publications/989/?v=1

  18. The Ames Test

    03 Jan 2019 | Teaching Materials | Contributor(s):

    By Nathan Goodson-Gregg, Elizabeth A. De Stasio

    Introduction to the Ames Test, published as GSA Learning Resource

    https://qubeshub.org/publications/987/?v=1

  19. EvolSeq

    11 Sep 2018 | Teaching Materials | Contributor(s):

    By Tony Weisstein1, John R Jungck2

    1. Truman State University 2. Interdisciplinary Science Learning Center at the University of Delaware

    An Excel worksheet that simulates the molecular evolution of DNA sequences.

    https://qubeshub.org/publications/776/?v=1

  20. Modifying HHMI Anole Resources: Using Image J to Quantify Ecomorphs and Tree-thinking to Explore Evolutionary Hypotheses

    18 Jan 2018 | Teaching Materials | Contributor(s):

    By Kristine Grayson

    University of Richmond

    I recombined the HHMI resources to have the students perform the image analysis from Virtual Lab 1 in Image J and explore the evolutionary principles in the Lizard Phenology modules

    https://qubeshub.org/publications/311/?v=1

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