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    Advanced Student Molecular Case Study Authorship Scaffolded Project and Rubric
    Instructions, assignment prompts, and a rubric for assessing advanced undergraduate authorship of molecular case studies
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    Collaborative case writing and field testing with Molecular CaseNet brings together discipline specific expertise for innovative pedagogical tools in the classroom
    Molecular case studies (MCS) use an interesting story as a hook , followed by exploration of biochemistry of one or more molecules of interest.  They can be useful in teaching about macromolecule...
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    CRISPR Gene Editing: Designing the gRNA and Donor Template
    In this adaptation, students learn how CRISPR/Cas9 is used in bacterial immunity and gene editing. Students create both a gRNA target and a donor template to edit a gene. Mutations can be from the...

    Keywords: geneticseducationcell biologymolecular biologymutationStem cellsstructure-functionmolecular visualization and analysis3D protein structure /function analysisCRISPR/Cas9crisprDNA mutationPiwiPDBMolecular Case StudyPiwi Matters

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    COVID-19: On the way to a vaccine
    This multi-part case study introduces the reader to the SARS-CoV-2 virus origins, the molecular basis of the infection, the development and severity of symptoms, and treatment.

    Keywords: BLASTprotein structure modelingmolecular visualization and analysisCOVID19PDB

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    Drugging SARS-CoV-2
    This case study leads students through the process of proposing a drug for a novel protein. The Mpro protease of SARS-CoV-2 is explored in detail within the PDB. Aligns with first semester...

    Keywords: viruscoronavirusPDBSARS-CoV-2proteasedrug design

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    Understanding COVID-19 Biology to Design a Vaccine
    This multi-part case study introduces the reader to the SARS-CoV-2 virus, replication, and treatment. Additional worksheets introduce students to bioinformatics tools of 3-D protein visualization...

    Keywords: BLASTprotein structure modelingmolecular visualization and analysisCOVID19PDB

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    Hemoglobin bioinformatics
    This is an introduction to bioinformatics using hemoglobin as an example. The worksheets introduce students to resources to explore the DNA, RNA and polypeptide linear structure with a brief...

    Keywords: bioinformaticsHemoglobinBLASTsickle cell diseaseMolecular Case StudyClustal OmegaMolCaseNet

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    Plant Defenses and Bioprospecting Mini-case Study
    This narrative mini-case study for use in undergraduate ecology courses reviews plant defense theory within the context of bioprospecting. Students learn about factors affecting plant defenses and...
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    Climate Diagrams Mini-Case Study for Ecology
    This mini-case study provides undergraduate ecology students with experience in how to read climate diagrams and how to put them together. The activity includes a discussion of actual and potential...
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    The Polar Bear of the Salt Marsh? Warming Tolerance Limits of Local Species
    National Center for Case Study Teaching in Science- In the adaptation exercise, students explore connections between saltmarsh sparrow declines and declining populations of local species that live...

    Keywords: Coastal wetlandsConnecticutmanagementnortheastsea-level risesalt marsh

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    Terrestrial Trophic Cascades & Population Structure
    In this activity, students will use data from natural parks to examine trophic cascades.

    Keywords: case studyBiodiversityplantsurban ecosystemsResource Typetrophic cascadesnational parksdeforestation

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    Case Study: Genetic Variation and Speciation in the Black Tailed Rattlesnake complex (Crotalus molossus)
    It is important for biology students to understand how genetic variation is related to the formation of species in nature. This module is intended for students to obtain first hand experience with...

    Keywords: phylogeneticscase studySpeciationtree readingsystematicsTree thinkingPhylogeographydistance learninggenetic variation

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    Yeti or not: Do they exist?
    Through this 4-part bioinformatics case study, students will be led through the forensic analysis of putative Yeti artifacts based on published findings.

    Keywords: case studybioinformaticsNIBLSEBLAST12S sequencingYeti

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    The Legacy of Redlining in Oakland, CA
    The issues of redlining and environmental justice will be introduced and used as a framework for a number of topics in the third part of the semester in a non-majors Environmental Science course.

    Keywords: environmental scienceenvironmental justiceredliningenvironmental racism

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    The tale of two fish: A case study on vicariance and allopatric speciation
    This mini-case study guides students through multiple lines of evidence that suggests the most likely sister species to the lake species Sardinella tawilis, the sister species being the marine fish...

    Keywords: ecologyfishevolutionary ecologySpeciationVicariancePhilippines

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    Prosecutor’s Fallacy and Mammograms Case Study
    An introduction to Prosecutor’s Fallacy, and False Positives/Negatives. By Dr. Diaz Eaton, Bates College, for use in DCS 105A, and inspired by Calling Bull & Calculated Risks.

    Keywords: ProbabilityExcelcalling bullMammogramsData UnderstandingVisualizing Outcomes

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    Modeling Trophic Interactions in Rice Agriculture: A Jigsaw Approach
    Students explore four different issues related to trophic interactions that affect modern rice agriculture practices and consider relationships between these issues using Lotka and Volterra...

    Keywords: mathematical modelLotka-Volterrajigsawfood chaintrophic cascadespredator-prey interactionsfood web

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    Understanding Trophic Interactions in Rice Agriculture: A Jigsaw Approach
    Students explore four different issues related to trophic interactions that affect modern rice agriculture practices and consider relationships between these issues.

    Keywords: jigsawfood chaintrophic cascadesfood web

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    Statistical Exploration of Climate Data
    In this module the students will learn some basic concepts in statistical thinking about data, with emphasis on exploratory data analysis.

    Keywords: modulelinear regressioncase studyclimate datamoving averagesin-class activity

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    Competition under the Sea: Exploring the competitive interaction between native and non-native seagrasses in the Caribbean
    A mini-case study that uses real-world data to explore the competitive interaction among seagrasses.

    Keywords: ecologycompetitionconservation ecologywater resource managementseagrassCaribbean

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