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    Kinetics of a Highly Conserved Enzyme - Carbonic Anhydrase
    This module contains exercises designed to introduce students to graphical representation of biological data. Students will explore the fundamental principles of enzyme kinetics including...

    Keywords: Excelintroductory biologycell biologygraphingslopeQuantitative reasoningdata visualizationquantitative biologyinterdisciplaryquantitative skillscorrelationenzyme functionInterpreting GraphsMichaelis-Mentenenzyme kineticsEnzyme activityenzyme inhibitionLinear and nonlinear analysisNIQBC2. Data and GraphsC4. mathematical modelsenzyme-substrateNIQB Interdisciplinary Quantitative Reasoningcarbonic anhydrase

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    Analysis of Amylase Activity
    This lab is an exploration of enzyme function and the effects of environmental conditions on the activity of the enzyme amylase. The lab utilizes analytical and graphing skills to assess enzyme...

    Keywords: data analysisintroductory biologyconcentrationgraphinglinear equationsBiochemistryscientific methodstandard curveenzyme functionMicrosoft ExcelInterpreting GraphsenzymesqbccCreate graphsInterpret graphsSolving Equations and Inequalitiesinterpret tablesAmylaseAlpha-amylaseEnzyme activityMaltoseDNS assayAbsorbancelab reportspectrophotometryregression linemanipulating equationsline of best fitgraphing by hand

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    Enzymes and the Rate of Chemical Reactions
    This module introduces rates of reactions in the context of understanding how enzymes affect chemical reactions. It is intended for an introductory biology audience.

    Keywords: calculushyperbolic equationsCellular Processesrates of change

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    Nature’s Flying Machines: The Evolutionary Relationship of Avian Form & Function
    In this series of activities, birds will be used as the model organism. The modules examine the connections between body form and function over time by investigating the relationship between avian...

    Keywords: evolutionary ecologyCommunity Ecology

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    Louse Genetics, Genomics, and Gene Function...Oh My!
    In this module, students will be investigating a louse gene with an unknown function to determine if it might be important in the evolution of the louse ecomorphs.

    Keywords: parasitesgenomicsgene sequence analysisFunctional Genomics

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    Louse and Human Coevolution
    This module examines the complicated co-evolution of Lice, Humans, and Great Apes

    Keywords: phylogeneticsBiodiversityparasitesCoevolutionhuman evolution

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    Exploring the evolution of caffeine biosynthesis enzymes
    Caffeine is a very common stimulant consume worldwide as tea, coffee, mate, cocoa, and chocolate. Ever wondered why plants make caffeine? Do all caffeine producing plants have the same enzymes for...

    Keywords: Bioinformatics EducationBioinformatics and Genomics

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    Plants We Eat: Learning Form and Function from Fruits and Vegetables
    This high school or undergraduate lab consists of four activities that guide students through learning about plant parts from the fruits and vegetables with which they are already familiar....
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    Movement: Nature's Flying Machines
    In this lab, you will explore the physics of flight, the adaptations that make powered flight possible, and the evolution of powered flight in vertebrates and invertebrates.

    Keywords: citizen sciencequantitative skillsDigital RepositoryFlight

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    BSL-4: Authorized Personnel Only
    National Center for Case Study Teaching in Science resource on the 2014 Ebola epidemic. This resource is also included in the NIBLSE Learning Resource Collection

    Keywords: infectious diseaseexperimental designbioinformaticsEbolaNIBLSECase It!PCRBLASTmultiple sequence alignmentPublished in National Center for Case Study Teaching in Sciencepolymerase chain reactionfebrile illnessvirusELISAenzyme linked immunosorbent assayfilovirusAfrica

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    Movement: Nature's Flying Machines (Online)
    Adapted for online learning: In this lab, you will explore the physics of flight, the adaptations that make powered flight possible, and the evolution of powered flight in vertebrates and...

    Keywords: citizen sciencequantitative skillsDigital RepositoryFlight

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    Curvature and Maximum Permissible Speeds
    In this activity students will compute the curvature of a section of commuter rail and use it to determine a safe speed at which a train should can round the corner without tipping or derailing....

    Keywords: data analysiscalculusnumerical approximationengineeringcalculus 3transportation

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    Birds and Lice: Reciprocal Natural Selection
    This exercise investigates the form and function of lice and their relationship to their bird host.

    Keywords: BiodiversityparasitesbirdsCoevolutionnatural history collections

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    Quantifying Bacterial Growth in the Guts and Hemolymph of Fruit Flies: Mathematical Modeling and Data Interpolation/Extrapolation
    In this activity, students will analyze raw data obtained from an experiment that explores the effect of overexpressing the Ssk protein in order to strengthen the intestinal barrier and prevent...

    Keywords: graphingexponential growthlinear modelsqbccinterpolationConcepts in Statistics and Precalculus Understanding exponential rates and linear slopesExtrapolation

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    AVIDA exercise on the role of mutation in evolution
    A tested exercise at the college freshmen level using AVIDA-Ed to generate and test a hypothesis about the relationship between mutation rate and the probability of evolving a useful function in...
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    Transpiration
    In this lab, students will examine differences between C3 and C4 plants in their transpiration rates.

    Keywords: plant physiologybotanylaboratoryResource Type

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    Making “sense” out of surface area to volume relationships
    Using a multimodal approach, the non-linear aspect of the surface area to volume relationship is explored. Students use their their senses of taste and sight to determine how smaller cells and...

    Keywords: active learningintroductory biologycell biologyquantitative skillskinesthetic learningLDC2023

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    A "Box of Lessons" for Exploring Biomolecular Structure and Function
    Biomolecular structure and function is emphasized as a core concept in a variety of community determined educational standards for biology and chemistry. Most curricula introduce students to the...

    Keywords: bioinformaticsproteinsRNADNAmolecular visualizationbiomolecular structurebiomolecular visualizationProtein Data BankPDBMolecular CaseNet FMN

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    CRISPR Gene Editing: Designing the gRNA and Donor Template
    In this adaptation, students learn how CRISPR/Cas9 is used in bacterial immunity and gene editing. Students create both a gRNA target and a donor template to edit a gene. Mutations can be from the...

    Keywords: geneticseducationcell biologymolecular biologymutationStem cellsstructure-functionmolecular visualization and analysis3D protein structure /function analysisCRISPR/Cas9crisprDNA mutationPiwiPDBMolecular Case StudyPiwi Matters

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    Homologous chromosomes? Exploring human sex chromosomes, sex determination and sex reversal using bioinformatics approaches
    In this four- part guided activity, students will learn about the structure and function of human autosomal and sex chromosomes, view and interpret gene maps, and gain familiarity with basic...

    Keywords: bioinformaticsNIBLSECourseSourceautosomehomologous chromosomeshomologous recombinationsex chromosomesex determinationsex reversal mutations

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