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    Joel E. Greengiant Learns About Peas: From Nucleotides to Selection
    This case study follows purveyors of peas, Joel E. and Jolene Greengiant, as they learn about the origin, biochemistry, genetics and eventual artificial selection of sweet (wrinkled) peas, all in...

    Keywords: geneticspopulation geneticsEvolutionintroductory biologycase studybiologyResources @ NSF - NCCSTSmeiosisMendel’s peaspea plantPisum sativumMendel’s Lawsmolecular geneticsmutationnucleotide insertionartificial selectionstarch synthesisstarch branching enzymeplant domesticationlegumesResources @ QUBES - Teaching & Reference

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    SKILLS DEVELOPMENT - Toxicology MSDT
    On this website you can find 6 learning modules on various topics in toxicology. These are self-paced student-centered online learning modules. You will receive a certificate of completion at the...

    Keywords: pathophysiologyregulatory toxicologyprinciples of toxicologybiochemistry and molecular geneticsprinciples of genetic toxicologyapplied systems toxicology

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    Collaborative case writing and field testing with Molecular CaseNet brings together discipline specific expertise for innovative pedagogical tools in the classroom
    Molecular case studies (MCS) use an interesting story as a hook , followed by exploration of biochemistry of one or more molecules of interest.  They can be useful in teaching about macromolecule...
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    Molecular Basis of Sickle Cell Disease
    This multi part case on hemoglobin structure as it relates to oxygen binding and sickle cell disease focuses on utilizing bioinformatics and molecular visualization tools to learn about the sickle...

    Keywords: Hemoglobinmolecular visualization and analysisintroductory bioinformaticssickle cell diseasePDBMolecular Case Studyoxygen bindingmyoglobinmolecular literacy3D protein structuresstructural representations

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    The Ames Test
    Introduction to the Ames Test, published as GSA Learning Resource

    Keywords: geneticsNIBLSEDNAames testassay

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    The Happy Blue Baby Hemoglobin
    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved.

    Keywords: mutationHemoglobinmolecular visualization and analysisPDBMolecular Case Study

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    COVID-19: On the way to a vaccine
    This multi-part case study introduces the reader to the SARS-CoV-2 virus origins, the molecular basis of the infection, the development and severity of symptoms, and treatment.

    Keywords: BLASTprotein structure modelingmolecular visualization and analysisCOVID19PDB

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    Box of Lessons: A Toolkit for Introducing Students to Biomolecular Structure and Function
    This is a poster describing a collection of open educational resources that were developed by faculty participating in the Molecular CaseNet Faculty Mentoring Network in Spring 2022. The collection...

    Keywords: bioinformaticsbiomolecular structureProtein Data Bankresources @ Molecular CaseNet

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    CRISPR Gene Editing: Designing the gRNA and Donor Template
    In this adaptation, students learn how CRISPR/Cas9 is used in bacterial immunity and gene editing. Students create both a gRNA target and a donor template to edit a gene. Mutations can be from the...

    Keywords: geneticseducationcell biologymolecular biologymutationStem cellsstructure-functionmolecular visualization and analysis3D protein structure /function analysisCRISPR/Cas9crisprDNA mutationPiwiPDBMolecular Case StudyPiwi Matters

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    Build Multiomic and Visualization Skills in Bioscience Lecture
    This resource promotes inclusive learning by using all free platforms to extend the central dogma to an applied experience. Genomics is focused on with literature reviews that are performed to...

    Keywords: geneticsBiochemistryBiology and Biochemistry EduationProtein StructureBioinformatics and GenomicsFunctional GenomicstranscriptomicsproteomicsRNAseqClinical genomicsprotein structure modelingInclusive teaching3D protein structure /function analysisinclusive classrooms3D protein structuresinclusivegene

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    Databases: A Study of Influenza
    This lesson introduces the student to the Influenza Research Database. Students will select Influenza genome sequences to see how they are related. Students tests hypotheses about evolutionary...

    Keywords: Bioinformatics EducationBioinformatics and Genomicsmolecular evolutionInfluenza

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    Drugging SARS-CoV-2
    This case study leads students through the process of proposing a drug for a novel protein. The Mpro protease of SARS-CoV-2 is explored in detail within the PDB. Aligns with first semester...

    Keywords: viruscoronavirusPDBSARS-CoV-2proteasedrug design

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    Data is the New Science - Modified and combined with Following the Data Module
    In this module, students will be introduced to some emerging biodiversity data resources. They will be asked to think critically about the strengths and utility of these data resources and apply...

    Keywords: data in the classroombiodiversity informaticsnatural history collection

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    Data is the New Science
    In this module, students will be introduced to some emerging biodiversity data resources. They will be asked to think critically about the strengths and utility of these data resources and apply...

    Keywords: data in the classroombiodiversity informaticsnatural history collection

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    Introductory Video and worksheets on Module 1 and 2 on "Sequence Similarity: An inquiry based and under the hood..."
    The video walks the students to complete Module 1 and 2 on Sequence Similarly and Alignment adapted from Tapprich (2019) and Hudson Alpha that teaches these modules within the context of the...

    Keywords: bioinformaticssequencingFASTANCBINIBLSEalgorithmsBLASTmultiple sequence alignmentsequence similarityBLOSUM scoring matrixCourseSource

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    Molecular CaseNet - Students Writing Cases - YouTube
    Biome Institute 2020, Summary Video

    Keywords: assessmentcase study creationMolecular structuremolecular visualizationMolecular Case Study

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    Exploration of the Human Genome by Investigation of Personalized SNPs
    To increase students' interest in their own genomes, this computer-based laboratory lesson is designed to be coupled with the opportunity for the students to be genotyped by the consumer sequencing...

    Keywords: bioinformaticsNIBLSECourseSourcegenomic wide association studiesUCSC genome browsersingle nucleotide polymorphism

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    Advanced Student Molecular Case Study Authorship Scaffolded Project and Rubric
    Instructions, assignment prompts, and a rubric for assessing advanced undergraduate authorship of molecular case studies
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    Biochemistry Take Home Exam - Alternative Assessment
    This take-home exam part has several creative activities that students can choose from to demonstrate their mastery of concepts in my one-semester General Biochemistry survey course. In addition...

    Keywords: BiochemistryInclusive teachingAlternative Assessmenttake home exam

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    Effect of the Intestinal Protein Snakeskin on the Lifespan of Fruit Flies: A Kaplan-Meier Survival Analysissource Draft (1)
    In this activity, students perform the Kaplan-Meier survival analysis on raw data obtained from an experiment that explores the effect of overexpressing the Snakeskin (Ssk) protein on the lifespan...

    Keywords: graphingBiochemistryhypothesis testingcalculus and biologyapproximating areas under curvesqbccCellular and Molecular BiologyCreate graphsInterpret graphsSolving Equations and Inequalitiesinterpret tablesConcepts in Statisticsusing statisticschi-square analysissurvival analysis

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