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    Molecular Basis of Sickle Cell Disease
    This multi part case on hemoglobin structure as it relates to oxygen binding and sickle cell disease focuses on utilizing bioinformatics and molecular visualization tools to learn about the sickle...

    Keywords: Hemoglobinmolecular visualization and analysisintroductory bioinformaticssickle cell diseasePDBMolecular Case Studyoxygen bindingmyoglobinmolecular literacy3D protein structuresstructural representations

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    Advanced Student Molecular Case Study Authorship Scaffolded Project and Rubric
    Instructions, assignment prompts, and a rubric for assessing advanced undergraduate authorship of molecular case studies
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    Maria vs Malaria
    This case study focuses on a specific enzyme Lactate Dehydrogenase (LDH) in the malarial parasite as a target for treating malaria.

    Keywords: bioinformaticsmolecular visualizationstructure-functionuniprotProtein Data BankMolecular Case StudyMolecular CaseNet

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    Morphological and Molecular Analysis of Plant Phylogeny and Diversity
    In this lab, students perform phylogenetic analyses on morphological and molecular data, and compare.

    Keywords: morphologyphylogenylaboratoryplantsdiversitymolecular analysis

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    Phylogenetic analysis using collections material: interpreting trait evolution by comparison of morphological and molecular genetic hypotheses
    Exercise spans two weeks, includes homework, and involves some groups of animals as well as plants. Emphasizes re-interpretation of morphological trait evolution following molecular genetic...

    Keywords: Evolutionmorphologyphylogenylaboratoryplantsbiological collectionsmolecular analysis

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    Morphological and Molecular Analysis of Plant Phylogeny and Diversity
    In this lab, students perform phylogenetic analyses on morphological and molecular data, and compare.

    Keywords: morphologyphylogenylaboratoryplantsmolecular analysis

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    EvolSeq
    An Excel worksheet that simulates the molecular evolution of DNA sequences.

    Keywords: molecular evolutionDNA

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    Using Undergraduate Molecular Biology Labs to Discover Targets of miRNAs in Humans
    In this lesson, we describe an easily adaptable lab module that can be used in existing undergraduate molecular biology lab courses to conduct authentic scientific research, published in CourseSource

    Keywords: molecular biologybioinformaticsNIBLSEgene regulationmicroRNAsgene expressionCourseSourcemiRNA

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    CRISPR Gene Editing: Designing the gRNA and Donor Template
    In this adaptation, students learn how CRISPR/Cas9 is used in bacterial immunity and gene editing. Students create both a gRNA target and a donor template to edit a gene. Mutations can be from the...

    Keywords: geneticseducationcell biologymolecular biologymutationStem cellsstructure-functionmolecular visualization and analysis3D protein structure /function analysisCRISPR/Cas9crisprDNA mutationPiwiPDBMolecular Case StudyPiwi Matters

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    COVID-19: On the way to a vaccine
    This multi-part case study introduces the reader to the SARS-CoV-2 virus origins, the molecular basis of the infection, the development and severity of symptoms, and treatment.

    Keywords: BLASTprotein structure modelingmolecular visualization and analysisCOVID19PDB

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    Morphological, Anatomical and Molecular Analysis of Plant Phylogeny and Diversity
    In this lab, students perform phylogenetic analyses on morphological, anatomical and molecular data, and compare.

    Keywords: morphologyphylogenylaboratoryplantsmolecular analysisstele architecture

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    The Effect of Climate Change on Butterfly Phenology - Intro Environmental Science
    In this module, students practice interpreting the relationship between variables before exploring changes in butterfly phenology through the use of natural history collections data.

    Keywords: ExcelResources @ ESA - TIEEgraphingquantitative literacyclimate changefmnphenologynatural history collectionsDIGbutterflyinterspecific interactions

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    Maria vs Malaria - AR Adaptation
    This case study focuses on a specific enzyme Lactate Dehydrogenase (LDH) in the malarial parasite as a target for treating malaria. Students will be able to view selected molecular views from the...

    Keywords: bioinformaticsAugmented RealityLarge class sizemolecular visualizationstructure-functionuniprotProtein Data BankMolecular Case StudyMolecular CaseNet

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    21st Century STEM Workforce Skills
    This activity includes a leadership assessment and associated exercise to encourage the development of 21st Century STEM Skills.

    Keywords: collaborationteam scienceleadership skills

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    Calling Bull in an Age of Big Data with R
    Use the calling bull course to introduce students to data, ethics, visualization, and R.

    Keywords: data scienceinformation literacydata literacyethicscallin bullcalling bull

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    Connecting Students to Citizen Science and Curated Collections
    This educational module utilizes the traditional plant collection experience to engage students with biodiversity data protocols and resources available in our information-rich digital age.

    Keywords: Biodiversityplantsnatural history collectionherbarium

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    Collaborative case writing and field testing with Molecular CaseNet brings together discipline specific expertise for innovative pedagogical tools in the classroom
    Molecular case studies (MCS) use an interesting story as a hook , followed by exploration of biochemistry of one or more molecules of interest.  They can be useful in teaching about macromolecule...
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    Understanding COVID-19 Biology to Design a Vaccine - Ethics supplement
    The adaptation to Understanding COVID-19 Biology to Design a Vaccine entails two ethics supplements. The first supplement addresses the use of off-label drugs in the pandemic (or other situation)....

    Keywords: bioethicsBLASTprotein structure modelingmolecular visualization and analysisethicsCOVID19PDB

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    Rescuing Data: Preserving Data for the Future
    Meet Diane Srivastava, director of the Canadian Institute for Ecology and Evolution, and learn how they sythesize and save biodiversity data.

    Keywords: metadatadigital datadata skillsBiodiversity Science

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    Biogeography of Hantavirus Hosts
    Using QGIS, this module introduces students to zoonotic pathogens, host biogeography, the "One Health" concept, forming hypothesis, and natural history museums within the Hantavirus system.

    Keywords: human-environmental interactionsmammalsbiogeographyhypothesis formulationdigitized natural history collectionshuman healthQGISzoonotic diseasesone healthrodentsPathogens

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