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    Using Undergraduate Molecular Biology Labs to Discover Targets of miRNAs in Humans
    In this lesson, we describe an easily adaptable lab module that can be used in existing undergraduate molecular biology lab courses to conduct authentic scientific research, published in CourseSource

    Keywords: molecular biologybioinformaticsNIBLSEgene regulationmicroRNAsgene expressionCourseSourcemiRNA

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    Effect of the Intestinal Protein Snakeskin on the Lifespan of Fruit Flies: A Kaplan-Meier Survival Analysissource Draft (1)
    In this activity, students perform the Kaplan-Meier survival analysis on raw data obtained from an experiment that explores the effect of overexpressing the Snakeskin (Ssk) protein on the lifespan...

    Keywords: graphingBiochemistryhypothesis testingcalculus and biologyapproximating areas under curvesqbccCellular and Molecular BiologyCreate graphsInterpret graphsSolving Equations and Inequalitiesinterpret tablesConcepts in Statisticsusing statisticschi-square analysissurvival analysis

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    CRISPR Gene Editing: Designing the gRNA and Donor Template
    In this adaptation, students learn how CRISPR/Cas9 is used in bacterial immunity and gene editing. Students create both a gRNA target and a donor template to edit a gene. Mutations can be from the...

    Keywords: geneticseducationcell biologymolecular biologymutationStem cellsstructure-functionmolecular visualization and analysis3D protein structure /function analysisCRISPR/Cas9crisprDNA mutationPiwiPDBMolecular Case StudyPiwi Matters

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    Learn Biological Sciences and Chemistry through cellular transport and concentration ( online and hands-on)
    Osmosis is a process by which by which solvent move from a region of lower solute concentration to region of higher solute concentration through a semi-permeable membrane. Cells utilize the process...

    Keywords: statisticsdata analysisbiologycell biologyconcentrationskillscellchemistryOsmosisSpectrophotometersolutionsolutesolvent

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    Understanding COVID-19 Biology to Design a Vaccine
    This multi-part case study introduces the reader to the SARS-CoV-2 virus, replication, and treatment. Additional worksheets introduce students to bioinformatics tools of 3-D protein visualization...

    Keywords: BLASTprotein structure modelingmolecular visualization and analysisCOVID19PDB

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    Instructor Guide: Integrating Project Leadership, Artificial Intelligence, Simulation and Google Tools to Understand Regulation of Gene Expression with the Lac Operon and Lactase Gene
    Scientific leadership and current artificial intelligence (AI) skills are important skills to be included in the course curriculum. Together or individually, these skills can enhance knowledge,...

    Keywords: Resources @ HHMI - BioInteractivebiologymolecular biologygenomicsArtificial Intelligencegene expressionleadershipgroup worklactosegoogle toolsSeniorPhET SimulationLactase

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    Advanced Student Molecular Case Study Authorship Scaffolded Project and Rubric
    Instructions, assignment prompts, and a rubric for assessing advanced undergraduate authorship of molecular case studies
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    Molecular Basis of Sickle Cell Disease
    This multi part case on hemoglobin structure as it relates to oxygen binding and sickle cell disease focuses on utilizing bioinformatics and molecular visualization tools to learn about the sickle...

    Keywords: Hemoglobinmolecular visualization and analysisintroductory bioinformaticssickle cell diseasePDBMolecular Case Studyoxygen bindingmyoglobinmolecular literacy3D protein structuresstructural representations

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    BSL-4: Authorized Personnel Only
    National Center for Case Study Teaching in Science resource on the 2014 Ebola epidemic. This resource is also included in the NIBLSE Learning Resource Collection

    Keywords: infectious diseaseexperimental designbioinformaticsEbolaNIBLSECase It!PCRBLASTmultiple sequence alignmentPublished in National Center for Case Study Teaching in Sciencepolymerase chain reactionfebrile illnessvirusELISAenzyme linked immunosorbent assayfilovirusAfrica

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    COVID-19: On the way to a vaccine
    This multi-part case study introduces the reader to the SARS-CoV-2 virus origins, the molecular basis of the infection, the development and severity of symptoms, and treatment.

    Keywords: BLASTprotein structure modelingmolecular visualization and analysisCOVID19PDB

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    Computational Biology using R
    This is an introductory level course on computational biology.

    Keywords: simulationmoduleRcourseprojectsolutions

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    Studying phylogeny by producing phylogenetic trees of primates using morphological and molecular characteristics.
    An assignment constructing phylogenetic trees using shared, derived morphological traits and molecular differences among 18 primate species and two outlier species has been developed. Skull and...
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    The Ames Test
    Introduction to the Ames Test, published as GSA Learning Resource

    Keywords: geneticsNIBLSEDNAames testassay

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    Quantifying and Visualizing Campus Tree Phenology
    This lesson, published on CourseSource, enables collaborative teams to collect, quantify, and analyze observable seasonal changes in nature.

    Keywords: ecologyBiodiversityphenologyplant biologyCourseSource

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    Instructor Guide : Integrating Leadership Skills, Data Science, Artificial Intelligence, Simulation and Google Tools to learn Physics
    Scientific, leadership and recent artificial intelligence skills are integral frameworks of the curriculum. All of them together or individually can enhance knowledge, critical thinking and...

    Keywords: simulationactive learningstembiologyassessmentdata scienceteachingphysicschemistrylearningArtificial Intelligencescienceleadership skillsgoogle toolsinstructor guide

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    A CURE in traits and species distributions: Reproductive modes, range sizes, and natural history collections
    This course-based undergraduate research experience (CURE) focuses on developing hypotheses about how traits influence the range sizes of species. Topics with substantive content include symbioses,...

    Keywords: Evolutionbiostatisticsecologynatural history collectionsSymbiosisspecies distributionsherbariumplant functional traitsLichenReproductive biologyAppalachian mountains

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    Turning ecological research into engaging online modules for undergraduates through Gala/OCELOTS
    Learn how to create and implement online modules in tropical ecology for undergraduates. In an NSF-funded network, researchers and specialists in 4DEE, pedagogy, interactive data tools, and media...

    Keywords: tropical biologyOCELOTSLDC2023

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    Islands as a Tool for Teaching Ecology and Evolution
    Module for Ecology & Evolution course covering island biogeography principles, The scientific process and hypothesis testing, statistical methods (t-tests, regression), and online database use...

    Keywords: moduleResources @ AIM-UP!species richnessBiodiversityIsland biogeographyAIM-UP

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    Teaching RNAseq at Undergraduate Institutions: A tutorial and R package from the Genome Consortium for Active Teaching
    This lesson plan was created to teach RNAseq analysis as a part of GCAT-SEEK network. It is provided here, both in finished form and with the modifiable source code, to allow flexible adaptation to...

    Keywords: statisticsR programming languagebioinformaticsNIBLSERNAseqgene expressionCourseSourcecomputer programming

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    Investigating the ecological value of migratory fishes on stream ecosystems in southern Appalachia
    Using the Ecological Society of America’s Four-Dimensional Ecology Education (4DEE) framework, students apply ecological concepts such as energy flow, nutrient cycling, migration, and climate...

    Keywords: Stream ecologynutrient cycling4DEE Frameworkfish migration

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