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    Genome Solver - A bioinformatics pipeline for community science
    The Genome Solver was an NSF-funded project developed as a way to train undergraduate life science faculty in basic web-based tools for bioinformatics. As part of the project we developed a one-day...

    Keywords: phylogeneticsbacteriophagebacteriaHorizontal Gene transferGenome Analysis

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    Using CRISPR-Cas9 to teach the fundamentals of molecular biology and experimental design
    One of the challenges of inquiry-based research experiences is balancing the instruction on skills and techniques with data generation and analysis. This is especially true in technique heavy...

    Keywords: experimental designcrisprmolecular technique

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    Outside the Norm: Using Public Ecology Database Information to Teach Biostatistics
    Biology students’ understanding of statistics is incomplete due to poor integration of these two disciplines. In some cases, students fail to learn statistics at the undergraduate level due...

    Keywords: biostatisticshypothesis testingexperimental design

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    Using Raw Sequence Data to Analyze Tumor Suppressor Mutations
    Learning to identify DNA sequence variants from raw sequencing data (electropherograms) is a basic molecular biology skill with applications to basic research and clinical practice. Yet learning to...

    Keywords: bioinformaticsmutationDNAgenomic visualizationparts of a geneclinical consequencesraw data

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    Linking Genotype to Phenotype: The Effect of a Mutation in Gibberellic Acid Production on Plant Germination
    Basic concepts in genetics and plant development are often taught in lecture courses without a lab component. This approach provides students with the content knowledge, but fails to make...

    Keywords: geneticsdevelopmentmutationgerminationplantmodel organismGenotype/PhenotypeHormoneSeed

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    Lesson II - Databases
    Genome Solver began as a way to teach undergraduate faculty some basic skills in bioinformatics; no coding or scripting is required. Lesson II introduces the principal databases for microbial...

    Keywords: Bioinformatics EducationBioinformatics and Genomics

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    Yeast Scramble Lab Manual v3
    This laboratory manual includes protocols for SCRaMbling of yeast cells as well as phenotypic characterization. Appropriate student exercises are also included. This resource was developed as part...
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    Pre-lesson: Introduction to BLAST
    Genome Solver began as a way to teach undergraduate faculty some basic skills in bioinformatics; no coding or scripting is required. This pre-lesson introduces the BLAST tool.

    Keywords: Bioinformatics EducationBioinformatics and Genomics

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    Pre-lesson: Introduction to BLAST
    Genome Solver began as a way to teach undergraduate faculty some basic skills in bioinformatics; no coding or scripting is required. This pre-lesson introduces the BLAST tool.

    Keywords: Bioinformatics EducationBioinformatics and Genomics

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    Mini-Workshop August 14, 2020
    We reviewed the materials available on Genome Solver (other lessons here) and described our new python pipeline for examining horizontal gene transfer and a new synteny lesson in detail.

    Keywords: Bioinformatics Education

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    Yeast Scramble Lab Manual
    This laboratory manual includes protocols for SCRaMbling of yeast cells as well as phenotypic characterization. Appropriate student exercises are also included. This resource was developed as part...
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    Lesson III - Annotation
    Genome Solver began as a way to teach undergraduate faculty some basic skills in bioinformatics; no coding or scripting is required. Lesson III introduces Annotation, or assigning meaning to all...
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    Lesson III - Annotation
    Genome Solver began as a way to teach undergraduate faculty some basic skills in bioinformatics; no coding or scripting is required. Lesson III introduces Annotation, or assigning meaning to all...
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    Lesson V - Phylogenetics
    Genome Solver began as a way to teach undergraduate faculty some basic skills in bioinformatics; no coding or scripting is required. Lesson V is an introduction to Phylogenetics.

    Keywords: Bioinformatics EducationBioinformatics and Genomics

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    Lesson IV - Comparative Genomics
    Genome Solver began as a way to teach undergraduate faculty some basic skills in bioinformatics; no coding or scripting is required. Lesson IV, Comparative Genomics, discusses some of the tools...

    Keywords: Bioinformatics EducationBioinformatics and Genomics

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    Lesson VI - The Community Science Project
    Genome Solver's Community Science Project was developed as a way to use the skills taught in the previous lessons. We're asking members of the community to provide instances of potential phage...

    Keywords: Bioinformatics EducationBioinformatics and Genomics

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    Ethics of Metabolic engineering
    This is an ethical reflection for students on an issue in metabolic engineering and the potential for "home-brew" morphine. The case study asks students to reflect on material in the linked...

    Keywords: biostatisticsstatistical analysisavian malariaSummer Workshop 2018

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    Ethics of Gene Editing
    This is an ethical reflection for students on an issue in gene editing. The case study asks students to reflect on material in the two linked articles. Also included is the grading rubric.

    Keywords: biostatisticsstatistical analysisavian malariaSummer Workshop 2018

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    The Genomics Education Partnership: Introducing Undergraduates to Research by Engaging Them in Genome Annotation
    Since 2006, the Genomics Education Partnership (GEP; http://gep.wustl.edu) has helped faculty bring genomics research experiences into the undergraduate curriculum.

    Keywords: undergraduate researchGenome annotationGEPgenomics education

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    Genome Sequence Data in R using Biostrings (Swirl Lesson)
    By the end of this lesson, students should be able to load FASTA files into R as DNAStringSets and use width() and alphabetFrequency(), combined with other functions like sum() and mean(), to...

    Keywords: R programming languagecourse-based undergraduate research experienceBioinformatics and GenomicsCURECUREscourse-based research experiences (CUREs)STEM CUREsComparative genomicsBioconductor

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