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    Splicing it Together: Using Primary Data to Explore RNA Splicing and Gene Expression in Large-Lecture Introductory Biology
    At the heart of scientific ways of knowing is the systematic collection and analysis of data, which is then used to propose an explanation of how the world works. In this two-day module, students...

    Keywords: gene regulationtranscriptiongene expressioncentral dogmarepressoralternative splicingmRNA processingActivatorTranscription factors

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    Discovering Prokaryotic Gene Regulation by Building and Investigating a Computational Model of the lac Operon
    The ability to construct and reason through a biological system is an important skill to develop in science education. This level of understanding forces students to recognize the interrelatedness...

    Keywords: prokaryotesgene regulationLac Operoninducible operon

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    The Great Petunia Carnage of 2017: A Clicker Case Study Using Petunias to Describe the Effect of Genetic Modification on the Biochemistry of Flower Color and Phenotype in Plants
    In this single class period case study, students examine the difference between genotype and phenotype by studying the mechanisms by which commercially available petunias have been bred to have...

    Keywords: case studyGenetic ModificationsBiochemistry of Flower ColorGMO regulationsGenotype-Phenotype Connections

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    9-152-HorizontalBeam-ModelingScenario
    This scenario is designed to lead students to discover a differential equation that models the vertical deflection of a horizontal beam under different boundary conditions.

    Keywords: Polynomial dynamical systembeamcantilever

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    Circle Train Problem TCM 2018_Hernandez.pdf - Google Drive
    In this math modeling lesson, students build mathematical models for the horizontal and vertical position of a train moving along a circular track. The math topics includes transformations of...

    Keywords: mathematical modelTrigonometryPrecalculusdata collectionLoggerProtransformation of functionsparametric equations

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    3-042-CatapultLaunch-ModelingScenario
    We maximize the range of a projectile by backing up an incline in the opposite direction of the range to give some initial lift. Find the position on the hill from which to launch the projectile to...

    Keywords: projectile motioncatapultuphilllaunch angle

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    Regulation of Gene Expression and Adipogenesis by PPAR-γ
    Students learn about transcriptional regulation of PPAR-γ, an important controller of adipose tissue stores and energy metabolism through a drawing/coloring activity of the different components...

    Keywords: gene expressionsmall group worktranscriptional regulationadipose tissuefat metabolismrepressor

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    2002-Chai-Optimal initial angle to fire a projectile
    Assume a projectile is fired without air resistance and lands at a height y above its initial vertical position. What is the optimal initial angle of firing to maximize the horizontal distance...

    Keywords: optimizationprojectile motionlaunch angle

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    Plate Tectonics: GPS Data, Boundary Zones, and Earthquake Hazards (Project EDDIE)
    Students work with high precision GPS data to explore how motion near a plate boundary is distributed over a larger region and hypothesize the area over which boundary-related earthquake hazards...
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    Circle Train Math Modeling Task
    This math modeling task is appropriate for high school Precalculus students. The students use their knowledge of transformations of trigonometric functions to create models for horizontal and...

    Keywords: mathematical modelTrigonometric Functionsparametric equationstransformations of functions

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    3-045-RampBounce-ModelingScenario
    Students build two projectile motion models (1) a one-dimensional model for a vertically falling ball from a fixed distance until it hits an inclined ramp and (2) a two-dimensional projectile...

    Keywords: projectile motioninclined rampcoefficient of restitutionoptimal anglebounce

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    Louse Genetics, Genomics, and Gene Function...Oh My!
    In this module, students will be investigating a louse gene with an unknown function to determine if it might be important in the evolution of the louse ecomorphs.

    Keywords: parasitesgenomicsgene sequence analysisFunctional Genomics

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    Neochromosomes: Creating transcriptional units with yeast Golden Gate assembly
    This resource is a series of protocols using the yeast Golden Gate (yGG) method as developed by Neta Agmon and Leslie Mitchell in Jef Boeke’s lab to assemble a functional yeast gene with...
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    Tackling "Big Data" with Biology Undergrads: A Simple RNA-seq Data Analysis Tutorial Using Galaxy
    Analyzing high-throughput DNA sequence data is a fundamental skill in modern biology. However, real and perceived barriers such as massive file sizes, substantial computational requirements, and...

    Keywords: bioinformaticsDNA sequenceRNAseqgene expression

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    Follow the Sulfur: Using Yeast Mutants to Study a Metabolic Pathway
    Students are frequently overwhelmed by the complexity of metabolic pathways and they think they have "learned" the pathway when they have memorized the individual reactions.  This...

    Keywords: SelectionyeastMetabolismcysteinemediamethioninemutantPathwaysulfur

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    The Science and Ethics of Gene Drives: An Active Learning Lesson in Genetics
    Coursework connecting biology to socially relevant issues and ethical questions can help students think about biology in interdisciplinary terms. Gene drives represent one topic involving both...

    Keywords: bioethicsCRISPR/Cas9Genetic modificationGene drives

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    A Phylogenetic Analysis of the Evolution of the CRYAA Gene Across Vertebrates
    Although the divergence of the aA-crystallin protein from other heat shock proteins has been examined, the extent to which the CRYAA gene controlling it has evolved across vertebrate species...

    Keywords: phylogeneticsvertebrates

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    Understanding Gene Prediction Programs
    Introduces students to the key biological concepts underlying computational gene prediction. Outcomes include ability to analyze and evaluate output of gene prediction programs, and reflect on...

    Keywords: Genome annotationSEA-PHAGESgene predictiongenemarkcoding potentialcodon biassix frame translation

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    2017-GR_Gustafson-Differential Equations Course Materials
    There are many applications from compartment and cascade analysis, recycling brine tank, home heating with multiple rooms, chemostat, microbes, heartbeats, lidocaine, nutrient flow in an aquarium,...

    Keywords: chemostatmicrobesbiomassforecastingtransfercompartmentpesticidesearthquaketankheatinglidocainebrineheartbeatsnutrient flowaquariumelectric networkscircuitsloggingbuildingcascade

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    Module 6: Alternative Splicing
    This module explores how multiple different mRNAs and polypeptides can be encoded by the same gene. After completing this module students will be able to explain how alternative splicing of a gene...

    Keywords: geneticsdata visualizationmolecular biologygenomicsexonintronalternative splicingSimilarity searchesMessenger RNA

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