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    Instructor Guide: Integrating Project Leadership, Artificial Intelligence, Simulation and Google Tools to Understand Regulation of Gene Expression with the Lac Operon and Lactase Gene
    Scientific leadership and current artificial intelligence (AI) skills are important skills to be included in the course curriculum. Together or individually, these skills can enhance knowledge,...

    Keywords: Resources @ HHMI - BioInteractivebiologymolecular biologygenomicsArtificial Intelligencegene expressionleadershipgroup worklactosegoogle toolsSeniorPhET SimulationLactase

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    Connecting Viral Pandemics to Ecological Population Growth Models
    In this activity students use the HHMI Population Growth Models interactive to explore R0 for diseases and discuss the importance of connecting population ecology to current events like the...
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    Stem Cells in Planaria Regeneration and Wound Healing
    Discussion questions to help guide students examining a graph of number of mitoses vs time for planaria injured or had amputations of their tails.

    Keywords: Stem cellsregenerationplanaria

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    Is bigger always better? An investigation on the effect of drought on different sizes of trees
    This data set was compiled from worldwide data to examine the effects of drought on trees. Included in the dataset are measurements of growth and mortality as they relate to the size category of...

    Keywords: statisticsforest ecologydata analysisclimate changeANOVAGraphing Functionsforest health

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    Sickle Cell Disease Case Study
    A short film explores the evolutionary connection between an infectious disease, malaria, and a genetic condition, sickle cell anemia. The animation explores the genetic causes and biological...

    Keywords: HHMI BioInteractive

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    Regulation of Gene Expression and Adipogenesis by PPAR-γ
    Students learn about transcriptional regulation of PPAR-γ, an important controller of adipose tissue stores and energy metabolism through a drawing/coloring activity of the different components...

    Keywords: gene expressionsmall group worktranscriptional regulationadipose tissuefat metabolismrepressor

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    Geoscience Methods and Resources for K-5 Pre-Education Majors
    : Exploring Geoscience Methods was an excellent capstone experience for Elementary Education Majors. The class I used this module with was 24 students of various backgrounds and academic...

    Keywords: geneticsvideosQUBESecologyResources @ HHMI - BioInteractiveMathematical Biologycalculusjavaorganismal biologyquantitative biologybioinformaticsneurosciencegenomicscancerSecondaryyoutubemicrobiomeFaculty Mentoring NetworksalamanderCapture mark-recaptureAudience level - Introductory UG - majorsAudience level - Introductory UG - non-majorsecosystemsgenetic basis of diseasebiology of cellshuman reproductionfood chainIntroduction to Modelingrandom number generatorPost-secondaryLower DivisionPossible TasksModeling ProjectBuildCompareEvaluateexponential decayrecursionabsorptionelimination

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    Examining human impacts on tusk evolution in elephants using authentic research data using Serenity
    In this activity students explore and analyze real, authentic research data paired with HHMI’s “Selection for Tuskless Elephants” video in a hands-on investigation of human impacts on elephant...
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    Amylase Copy Number and Diet
    An adapted module from HHMI Spreadsheet Tutorials using amylase data for students to gain data analysis and excel skills

    Keywords: Scientific ProcessStatistics and MathScientific Methodology

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    Calculating Lifetime Cancer Risk Resulting from DNA Replication
    An expanded case study adapted from an HHMI Data Point on Cell Division and Cancer Risk using Figure 1 from Tomasetti, C. and Vogelstein, B. (2015).

    Keywords: cancerScientific ProcessStatistics and MathScientific Methodologybiology of cellscell growth and divisionHigh School

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    Electrical and chemical communication in the nervous system
    This activity guides students through an online tutorial to examine the electrical and chemical communication of neurons.

    Keywords: introductory biologyneurobiologyanatomy and physiologyCell communication

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    Investigating Biomes with BiomeViewer
    This interactive classroom activity facilitates student learning about biodiversity through an investigation of biomes (what they are, how they're defined, their global distribution) using a free...

    Keywords: BiodiversityEcosystem EcologyBiomeViewerbiomes

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    Modeling Trophic Interactions in Rice Agriculture: A Jigsaw Approach
    Students explore four different issues related to trophic interactions that affect modern rice agriculture practices and consider relationships between these issues using Lotka and Volterra...

    Keywords: mathematical modelLotka-Volterrajigsawfood chaintrophic cascadespredator-prey interactionsfood web

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    Understanding Trophic Interactions in Rice Agriculture: A Jigsaw Approach
    Students explore four different issues related to trophic interactions that affect modern rice agriculture practices and consider relationships between these issues.

    Keywords: jigsawfood chaintrophic cascadesfood web

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    Regulation Across Scales: Data Points Icebreaker Jigsaw
    Students examine regulation at cellular, physiological, and ecological scales in a data-based jigsaw to explore how double-negative logic operates across biological systems. This was used as a...

    Keywords: pathwaysgene regulationtrophic cascadesregulationcross-scalecholesterol synthesisLac OperonYellowstone

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    Regulation Across Scales: Data Points on How Life Works
    We examined the scientific literature for simple, data-based illustrations of double-negative logic in the regulation of biological systems as described by Sean B. Carroll in his text, The...
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    Maternal transmission of microbiome
    Understanding the cascading effects of the transfer of maternal microbiome during a vaginal birth (vs. a c-section) to the well-being of a newborn.

    Keywords: microbiomehuman reproduction

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    Workshop Report: Summer 2020 Virtual CRISPR in the Classroom
    As innovations and developments in genome editing technologies using CRISPR-Cas systems progress, the need to disseminate relevant knowledge and build skills among the next generation of young...

    Keywords: geneticscrisprGenome Analysisgene editingbacterial immunity

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    Attract or Defend? Secondary Compounds among tissues in two species of Lupine (Fabaceae)
    This plant-biology data analysis module compares concentrations of defensive alkaloid compounds among tissue types in two species of the flowering-plant Lupine (Fabaceae). Students practice with...
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    Opioid crisis: exploring the neurophysiology of opioid receptor signaling
    Using this dataset, we explore how opioids affect the electrical activity of neurons when exposed to different opioid receptor agonists and antagonists.

    Keywords: opioid epidemic

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