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    Discovering Prokaryotic Gene Regulation by Building and Investigating a Computational Model of the lac Operon
    The ability to construct and reason through a biological system is an important skill to develop in science education. This level of understanding forces students to recognize the interrelatedness...

    Keywords: prokaryotesgene regulationLac Operoninducible operon

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    Cell Aggregation and Sphere Packing
    This module introduces the calculation of packing density in the context of understanding cell aggregation and arrangement. It is intended for an introductory biology audience.

    Keywords: RatiosGeometryInequalitiesCell StructureCell GrowthCell AggregationSphere Packing

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    An undergraduate bioinformatics curriculum that teaches eukaryotic gene structure
    Gene structure, transcription, translation, and alternative splicing are challenging concepts for many undergraduates studying biology. These topics are typically covered in a traditional lecture...

    Keywords: bioinformaticsGenome BrowsergenomicsRNAseqsplicingComputer ModelGene Structure

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    HITS: A network to create inquiry-based case studies that make high-throughput approaches and discovery accessible
    Poster on the work of the NSF-funded High-throughput Discovery Science & Inquiry-based Case Studies for Today’s Students (HITS) Research Coordination Network. Presented at the 2021 BIOME Institute.

    Keywords: case studieshigh-throughputHITSHigh-throughput Discovery Science & Inquiry-based Case Studies for Today’s Students2021 BIOME

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    E. coli Citrate Use
    EvoEd module on citrate use in E.coli

    Keywords: modulephylogeneticsecologycell biologymolecular genetics

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    Science of Sorting
    Children possess an innate curiosity about the natural world. This Discovery Trunk explores the topic of sorting, or classification, in the study of life science.

    Keywords: species interactionsphylogenyscience educationPropertytaxonomyindividual traitsLife ScienceSortOrganizationReproductionclassifycharacteriesticlivingnonlivingobjectsadvantagedichotomous keyliving systemsoffspringphysical traitbehavioral traitcladecladogramtaxonomistnatural worldkingdomsbinomial nominclatureone class periodgradesK-8K-8

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    Long-read Sequencing Technology
    This 50 minute lecture on long-read sequencing technology covers the following items: 1) Review of RNA-Seq Short-read Sequencing, 2) Overview and benefits of Long-read Sequencing, 3) Oxford...

    Keywords: sequencingDNA sequenceRNA sequencingNanoporepacbiopacific biosciences

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    GEA Introductory lesson on RNA-Seq
    This RNA-Seq lesson uses the CyVerse VICE Platform and Jupyter notebooks to examine the expression of the leptin gene in samples from a mouse experimental design evaluating diet (high-fat vs....

    Keywords: data sciencebioinformaticsGenome BrowserRNAseqhigh throughput sequencingmRNAAlignmentNCBI Sequence Read Archive

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    Does Organelle Shape Matter? Exploring Cell Shape through the Allen Cell Explorer and High-content Microscopy Datasets
    The morphology and localization of structures inside the cell are often assumed to fit the ideal images found in biology textbooks. This interrupted case study using high-throughput microscopy data...
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    Online Adaptation of the Cell Engineer/Detective Lesson
    One of the most fundamental themes of biology is the relationship between structure and function, which is particularly evident when it comes to cells; however, the traditional cartoon depictions...

    Keywords: cell functionCell StructureOrganelles

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    Module 3: Transcription, Part II: What Happens to the Initial Transcript Made by RNA pol II?
    This module teaches about the three key steps that are involved in converting the pre-mRNA into a mature mRNA: 1) The addition of a 5’ cap, 2) The addition of a 3’ poly(A) tail, 3) The removal of...

    Keywords: geneticsmolecular biologyGenome BrowsergenomicssplicingmRNAcDNA5' Cap3' Poly(A) TailRNA Maturation

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    Making bioinformatics tools classroom-friendly
    Poster on using Cyverse resources to make classroom that make using bioinformatics in the classroom a more manageable experience presented at the 2020 BIOME Institute: Cultivating Scientific Curiosity

    Keywords: bioinformaticsJupyterJupyter notebookBLASTCyVerseRNA sequencing

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    Cell Division and Rates of Population Growth
    This module introduces the exponential growth of cells in the context of understanding cell division. It is intended for an introductory biology audience.

    Keywords: exponential equationscell growth and divisionGeometric SeriesCell StructureOpenStaxgeometric equations

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    Doubling Time of Tumors
    This module introduces the calculation of potential doubling time of tumorous cells in the context of understanding the growth of a population of the cells. It is intended for an introductory...

    Keywords: linear regressionRatiosCell StructureOpenStaxCell Growth

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    The Science and Ethics of Gene Drives: An Active Learning Lesson in Genetics
    Coursework connecting biology to socially relevant issues and ethical questions can help students think about biology in interdisciplinary terms. Gene drives represent one topic involving both...

    Keywords: bioethicsCRISPR/Cas9Genetic modificationGene drives

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    Mitotic Index and Cell Division
    This module introduces the mitotic index in the context of understanding the dynamics of cell division in the root of a plant. It is intended for an introductory biology audience.

    Keywords: RatiosCell StructureCell GrowthchartCell DivisionMitotic Index

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    Cell Biology by the Numbers
    Vignettes that reveal how numbers serve as a sixth sense to understanding our cells

    Keywords: datacell biologyNumbersratesconcentrationMeasurementestimation

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    Cell Collective: Computational Modeling and Simulation Designed with the Classroom in Mind
    This working group collaborated on content and pedagogy surrounding the use of Cell Collective to integrate computational modeling and simulation into undergraduate biology curriculum.
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    Nucleoplasmic Index
    This module introduces the nucleoplasmic index in the context of understanding how the volume of organelles and cell contents change during the cell cycle. It is intended for an introductory...

    Keywords: RatiosInterpreting GraphsCell StructureCell GrowthNucleoplasmic Index

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    Homologous chromosomes? Exploring human sex chromosomes, sex determination and sex reversal using bioinformatics approaches
    Constructing a robust understanding of homologous chromosomes, sex chromosomes, and the particulate nature of genes is a notoriously difficult task for undergraduate biology students. In this...

    Keywords: bioinformaticsautosomehomologous chromosomeshomologous recombinationsex chromosomesex determinationsex reversal mutations

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