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    CRISPR Gene Editing: Designing the gRNA and Donor Template
    In this adaptation, students learn how CRISPR/Cas9 is used in bacterial immunity and gene editing. Students create both a gRNA target and a donor template to edit a gene. Mutations can be from the...

    Keywords: geneticseducationcell biologymolecular biologymutationStem cellsstructure-functionmolecular visualization and analysis3D protein structure /function analysisCRISPR/Cas9crisprDNA mutationPiwiPDBMolecular Case StudyPiwi Matters

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    An introduction to population matrix models: a swirl lesson
    Students will learn how to set up a population matrix model in R and use it for demographic analysis of a population, including projecting population growth, determining lambda and the stable age...

    Keywords: population dynamicsRpopulation growthonlinedemographypopulation projection modelquantitative biologypopulation modelmatrix modelspopulation ecologyage structurepopulation biologypopulation modelingSwirlDemographic processespopulationLeslie matrix

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    Why does Blood Flow Change? Investigating the Math of Blood Flow Dynamics
    This collection of activities explores the relationship between blood flow, pressure, and the factors of resistance through graphs and modeling direct and inverse variation.

    Keywords: quant biographingRatiosmathassessmentcollege algebraundergraduate educationphysiologyAnatomyhuman biologyvariationCardiovascular physiologyAnatomy & Physiologylab activityOpenStaxqbccmanipulate equationsUnderstanding fractionsChoosing modelsUnderstanding ratesEstimating answersUse elementary functionsCreate graphsInterpret graphsRates and ProportionsSolving Equations and Inequalities

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    Materials for Teaching the SIR Epidemic Model
    This web page contains materials created by faculty of the University of Nebraska-Lincoln Department of Mathematics to teach basic fundamentals of mathematical epidemiology.
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    Introduction to Data Management, Life History, and Demography
    Learning Goals: • explain importance of data management • identify elements of an organized data sheet • create & manipulate data in a spreadsheet • calculate vital statistics using life...

    Keywords: Resources @ ESA - TIEEdemographysurvivorshipdata managementlife tables

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    Antigen presentation and cytotoxic T lymphocytes (CTLs): elucidating a common roadblock for students
    Active learning resource for pre-Nursing anatomy and physiology lecture explaining antigen presentation to CTLs and how the CTLs recognize and destroy the pathogen using Biointeractive animations...

    Keywords: Resources @ HHMI - BioInteractiveimmune systemAnatomy & PhysiologyCell communication

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    Demography from "virtual cemeteries"
    This module is a modification of the Lanza module in TIEE Volume 8. Rather than requiring students to visit cemeteries outside of class, this modification has students collect data from online...

    Keywords: ecologyResources @ ESA - TIEEdemographysurvivorshiplife tables

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    Responses to Climate Change in California Chipmunks: Move, Adapt, or Die
    A series of three modules using data from natural history museum collections to examine responses to climate change in multiple chipmunk species. Elevation and morphological data, beginner skills...

    Keywords: statisticsmodelingmodulemorphologysummary statisticsmodulesclimate datamuseumsclimate changeundergraduate educationR programming languageprogrammingelevationnatural history museumsmammalssmall mammals community dynamicsmuseum collectionsVertebrate Morphologyopen educational resourceR programming environment

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    Data Analysis and Cancer
    This is a flipped classroom approach, students will learn the basic content about cell-signaling, p53, and transcription factors before class. During class students will focus on data analysis...

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymolecular biologydata interpretationBiological Data Analysiscell cyclemacromoleculesGenetic diseaseCell signaling

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    Teaching Population Dynamics with Data and HHMI BioInteractive
    Presented at NABT 2019, we demonstrate how the Population Dynamics Click & Learn resource can be customized for any organism - using the Lionfish invasion as an example

    Keywords: population growthHHMI BioInteractive

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    Exploring the Application of Genetic Concepts to the Process of Disease in a Pathophysiology Course for Undergraduate Nursing Students
    Poster on incorporating genetics concepts related to human disease into nursing courses presented at the 2019 BioQUEST & QUBES Summer Workshop
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    Cells of the Immune System
    This tutorial provides an overview of the immune system, concentrating on the roles played by B and T lymphocytes, and on the antigen-presentation system.
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    Targeting Infected Cells for Immune Defense
    This animation shows how a cell infected by a virus signals cytotoxic T cells to destroy itself.

    Keywords: Resources @ HHMI - BioInteractiveimmune systemAnatomy & PhysiologyCell communication

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    The p53 Gene and Cancer
    This tutorial describes the structure and function of the p53 protein, how its activity is regulated in cells, and how mutant versions of p53 can lead to cancer.

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymolecular biologymacromoleculesGenetic disease

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    Modification of "Exploring the population dynamics of wintering bald eagles through long-term data" module
    This module is a modification of the Beckstead et al. module in TIEE Volume 7. It includes a meta-cognition based model and self reflection, no statistics, and is organized to be done in 1-2...

    Keywords: Resources @ ESA - TIEEcase studypopulation ecologyendangered speciesconservation biologymigration ecology

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    Exploring the population dynamics of wintering bald eagles through long-term data
    pptx presentation & partially filled out student proposal worksheet

    Keywords: Resources @ ESA - TIEEcase studypopulation ecologyendangered speciesconservation biologymigration ecology

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    Exploring the population dynamics of wintering bald eagles through long-term data using R
    The purpose of this modification was to take the analyses that were done in Excel and have the students perform them using R. Students were not given any R code for this activity, as R code was...

    Keywords: Resources @ ESA - TIEEcase studyR programming languagepopulation ecologyendangered speciesconservation biologymigration ecologyggplot2

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    Investigating human impacts on local Hawaiian stream ecology
    Students learn about stream ecology on the island of Hawaii using data available through USGS and University of Hawaii websites and develop an understanding for potential stream changes due to...

    Keywords: climateStream ecologyHawaii CountyTopographyMap ReadingRainfall

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    Antibody Binding
    This module introduces the Scatchard equation in the context of understanding antigen binding and the properties of antigens. It is intended for an introductory biology audience.

    Keywords: linear equationshyperbolic equationsCellular Processes

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    Cell Division and the Presence of a Growth Factor
    This module introduces exponential growth, the Michaelis-Menten, and Lineweaver-Burk equations in the context of understanding how growth factors influence cell division. It is intended for an...

    Keywords: exponential equationshyperbolic equationsCell StructureCell Growthgrowth factor

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