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    Malawian Aquaculture Pond Ecosystem Challenge
    This case study challenges students to design a pond that will provide supplemental food security to a rural Malawian village. In the process they apply concepts of primary and secondary...
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    Traditional Ecological Knowledge and Natural History
    In this module, students will explore Western Science and Traditional Ecological Knowledge and review a case study of how the TEK of the Inuit provided a way of knowing and understanding the...

    Keywords: Traditional ecological knowledgeUnderstanding ScienceBowhead Whale

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    Sickle Cell Anemia using Nicholas’ Story
    The goal of this exercise is to introduce students to 3-D structures of biological molecules, visualize and manipulate them to understand their functions. The exercise also helps them see the...

    Keywords: Hemoglobinsickle cell diseaseMolecular Case Study

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    Hemoglobin cooperativity and adaptations to high altitude living
    This resource accompanies the "How does blood carry oxygen?" chapter in the Integrating Concepts in Biology etext. Students evaluate the cooperativity of hemoglobin and adaptations to high...

    Keywords: Integrating Concepts in Biology

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    Investigating the ecological value of migratory fishes on stream ecosystems in southern Appalachia
    Using the Ecological Society of America’s Four-Dimensional Ecology Education (4DEE) framework, students apply ecological concepts such as energy flow, nutrient cycling, migration, and climate...

    Keywords: Stream ecologynutrient cycling4DEE Frameworkfish migration

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    Calculating Lifetime Cancer Risk Resulting from DNA Replication
    An expanded case study adapted from an HHMI Data Point on Cell Division and Cancer Risk using Figure 1 from Tomasetti, C. and Vogelstein, B. (2015).

    Keywords: cancerScientific ProcessStatistics and MathScientific Methodologybiology of cellscell growth and divisionHigh School

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    Real World Scenarios in Non-Majors Biology
    Students in non-majors’ biology courses may not choose careers that require biology content knowledge; however, all will encounter science in their lives. We redesigned a non-majors...

    Keywords: geneticsVaccinesScientific ProcessGMOsviruses

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    Case Study — The Gender gap in 100-meter dash times
    In 2004, the journal Nature published a short tongue-in-cheek paper by Tatem and colleagues meant to critique common abuses in linear modeling while fitting data from the Olympic gold medal times...

    Keywords: calling bulltrack and fieldreproducing resultslinear modelingcritique

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    COVID-19: On the way to a vaccine
    This multi-part case study introduces the reader to the SARS-CoV-2 virus origins, the molecular basis of the infection, the development and severity of symptoms, and treatment.

    Keywords: BLASTprotein structure modelingmolecular visualization and analysisCOVID19PDB

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    Understanding COVID-19 Biology to Design a Vaccine
    This multi-part case study introduces the reader to the SARS-CoV-2 virus, replication, and treatment. Additional worksheets introduce students to bioinformatics tools of 3-D protein visualization...

    Keywords: BLASTprotein structure modelingmolecular visualization and analysisCOVID19PDB

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    COVID-19: Molecular Basis of Infection-ADAPTATION
    This case was written in Spring 2020 during the COVID-19 pandemic. It focuses on understanding the structure and interaction of the SARS-Cov-2 viral spike protein that facilitates infection in...

    Keywords: infectionvaccinemolecular visualization and analysisCOVID19PDBSARS-CoVMolecular Case Study

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    Bacteria to Brains in Backyard Coyotes: An Interdisciplinary Pedagogical Case Study
    Our interdisciplinary pedagogical case study explores the differences between rural and urban coyotes at the levels of organismal and community ecology. The focus is on how coyotes’ gut microbiomes...

    Keywords: Vision and Changeecologyintroductory biologyImmunologymicrobiologydietanimal behaviormicrobiomecore conceptscoyotesBraingut-brain axisImmunoReachcytokinedysbiosis

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    The Great Petunia Carnage of 2017: A Clicker Case Study Using Petunias to Describe the Effect of Genetic Modification on the Biochemistry of Flower Color and Phenotype in Plants
    In this single class period case study, students examine the difference between genotype and phenotype by studying the mechanisms by which commercially available petunias have been bred to have...

    Keywords: case studyGenetic ModificationsBiochemistry of Flower ColorGMO regulationsGenotype-Phenotype Connections

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    Molecular CaseNet - Developing and Using Molecular Case Studies at the Interface of Biology and Chemistry (RCN-UBE Introduction)
    A community of educators and scholars developing and using Molecular Case Studies (MCS), to explore the molecular basis of biological phenomena, understand real world problems, and their developing...

    Keywords: RCN-UBE Introduction

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    Globally endangered sea turtles of the Palmyra Atoll National Wildlife Refuge: A Focus on Scientific Analysis
    in this exercise students will make suggestions for designing a comprehensive research program, use survey data, critically analyze results, and devise methods for study.

    Keywords: case study

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    Coyote Habituation and a Scientist Spotlight on Dr. Christopher Schell
    Dr. Christopher Schell is an ecologist who uses a variety of techniques to study mammalian carnivores in urban areas. This scientist spotlight uses graphs from his study on parental habituation to...

    Keywords: conservation ecologyanimal behaviorurban ecologyInterpreting GraphsBLACK SCIENTISTS IN STEMcoyotes

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    An Interrupted Case Study on Urban Prairie Restoration
    Engaging students in meaningful discussions can be a challenging task for science instructors, especially in introductory courses. The story-telling approach used in case studies can increase...

    Keywords: urban ecologyPrescribed fireEcosystem Servicesecological restorationwoody encroachmentrangeland ecology

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    Teaching epidemiology and principles of infectious disease using popular media and the case of Typhoid Mary
    Allied health students often struggle to understand how particular content, such as epidemiology, connects to their future careers. This activity uses the case of Typhoid Mary as a foundation for...

    Keywords: epidemiologycase studyinfectous diseasepopular mediaTyphoid Mary

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    Applying Universal Design for Learning (UDL) Principles to Case Studies
    This is a presentation for the 2022 BIOME meeting.
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    Hypoxia: A Case Study in R
    Aquatic ecosystems are home to a complex intersection of physical and biological factors and an intersection of natural and anthropogenic factors. In the Chesapeake Bay, low oxygen events have...

    Keywords: data analysisOceanographyProject EDDIE

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