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    HSI - Student Research Journal - Vol.2 Issue 1 - Spring 2021
    The Headwaters Research Experience students have produced some fascinating research throughout our 10-week program. We encourage all to read their reports in our Vol. 2 - Issue 1 - Spring 2021...

    Keywords: scientific methodscience education

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    HSI - Student Research Journal - Vol.1 Issue 4 - Fall 2020
    The Headwaters Research Experience students have produced some fascinating research throughout our 10-week program. We encourage all to read their reports in our Vol. 1 - Issue 4 - Fall 2020...

    Keywords: scientific methodscience education

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    HSI - Student Research Journal - Vol.1 Issue 2 - Fall 2020 v.1.0
    The Headwaters Research Experience students have produced some fascinating research throughout our 10-week program. We encourage all to read their reports in our Vol. 1 - Issue 2 - Fall 2020...

    Keywords: scientific methodscience education

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    Quantitative Modules to Accompany General Biology Courses
    A collection of modules that were developed to accompany general biology courses and allow instructors to add quantitative examples in many of the topics in a standard GB sequence.

    Keywords: moduleintroductory biologymathmodulesprojectResources @ QUBES - Teaching & Reference

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    Quantitative biology: how educators that "buy-in" demonstrate greater productivity in teaching scholarship
    Poster presented at the University of Pittsburgh undergraduate research symposium on the impact of buy-in on productivity in faculty mentoring networks.

    Keywords: faculty mentoring networks

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    Modeling the Research Process: Authentic human physiology research in a large non-majors course
    Laboratory experiences in large-enrollment introductory science courses often utilize “cookie-cutter style” laboratory experiences due to the relative simplicity of setting up the lab...

    Keywords: data analysishypothesis testingexperimental designphysiology

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    Application of a Bacterial Experimental Evolution System to Visualize and Teach Evolution in Action: A Course-Based Undergraduate Research Experience
    Concepts of evolution are typically taught through examples of extremely long timescales, which do not always resonate broadly. Here, we describe a course-based undergraduate research experience...

    Keywords: EvolutionmutationcompetitionNatural Selectionregulationstructure and functionreproductive fitnessgenotype to phenotypehomologs

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    Pain Medication Treatment Modeling Project
    This classroom modeling project applies mathematical techniques to solve a problem related to drug dosage patterns. Suitable for high school or undergraduate students. Prerequisite: Calculus I.

    Keywords: Mathematical Biologycalculusexponential decayrecursionabsorptionelimination

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    Cancer Discovery Activities
    These two hands-on activities are based on a Howard Hughes Medical Institute 2013 Holiday Lectures on Science video (http://www.hhmi.org/biointeractive/cancer-genetic-disease-video-highlights)...

    Keywords: geneticsResources @ HHMI - BioInteractiveorganismal biologyneurosciencegenomicscancergenetic basis of diseasebiology of cellsHigh School

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    Evaluating the potential for immune escape: how likely is an antibody to protect against a specific SARS-CoV-2 variant?
    Commercial antibodies to the SARS-CoV-2 spike protein have been successfully used to treat people with COVID-19. Unfortunately, as the SARS-CoV-2 virus evolves, new variants have appeared that can...

    Keywords: course based undergraduate research experiencesBLASTmolecular modelingSARS-CoV-2antibodyNextstrainiCn3DSequence alignmentStructure alignment

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    Modeling the lac Operon to Understand the Regulation of Gene Expression in Prokaryotes
    This resource is a recitation activity designed for an introductory biology course in which students explore a lac operon simulation (https://qubeshub.org/resources/phetlacoperon).

    Keywords: simulationLac Operon

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    Joel E. Greengiant Learns About Peas: From Nucleotides to Selection
    This case study follows purveyors of peas, Joel E. and Jolene Greengiant, as they learn about the origin, biochemistry, genetics and eventual artificial selection of sweet (wrinkled) peas, all in...

    Keywords: geneticspopulation geneticsEvolutionintroductory biologycase studybiologyResources @ NSF - NCCSTSmeiosisMendel’s peaspea plantPisum sativumMendel’s Lawsmolecular geneticsmutationnucleotide insertionartificial selectionstarch synthesisstarch branching enzymeplant domesticationlegumesResources @ QUBES - Teaching & Reference

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    Figure of the Day - Adapted for Non-Majors
    Students use their number sense to make observations and come up with reasonable guesses or explanations for the patterns shown.

    Keywords: graphsmath attitudesResources @ BIOMAAPInterpreting Graphs

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    5Qs: An Activity to Support Students Develop Skills to Interpret Research Observations
    5Qs (five questions) is a simple pedagogy tool research mentors can use to help students think through their observations systematically, to draw supported conclusions, and to decide on next steps,...

    Keywords: researchMentorshipambiguitymodelling scientific thinkingencouraging independence

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    3-150-ItsABlastFurnace-ModelingScenario
    This project uses the steady-state heat equation to model the temperature distribution in an industrial furnace used for metal production, for example, a blast furnace.

    Keywords: steady stateheat equationinverse problemfurnace

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    6-029-TumorGrowth-ModelingScenario
    This modeling scenario guides a student familiar with single ordinary differential equation (ODE) models towards the development of a more complex system of two ODEs for describing the evolution of...

    Keywords: Pop_Growth Pilotlogisticcomparmenttumorsynthetic datasum of squares error

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    Data on Dead Zones and a Scientist Spotlight Featuring Benjamin Negrete, Jr.
    In this lesson, students plot data and interpret graphs of the metabolic responses of fish to hypoxic conditions. Then, students view and reflect on an interview with fish ecophysiologist Benjamin...

    Keywords: fishgraphinggraph interpretationhuman-environmental interactionsdata literacysocial justicemarineCODAP

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    How Many More Thymes & Herbivore Defense
    Adaptations to the How Many More Thymes? case study featuring terpene-based herbivore defense and pollinator attraction in Nicotiana plants.

    Keywords: food websgenotypephenotypeHerbivoryherbivoredeterrencemonoterpeneproducerchemotypeThymus vulgaristhymeMediterranean ecosystemchemical defensesManduca sextaNicotiana

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    Grassy Narrows and Muskrat Falls Dam: Hypothesis Testing and t-Tests
    Students are introduced to concepts of hypothesis testing using elementary hypothesis tests, t-tests, and p-values as they compare a given fish population for methylmercury levels (using real and...

    Keywords: statisticsmathematicsbiostatisticsecologybiologygraphingp-valuest-testshypothesis testingin-class activityZoologymercury biogeochemistrybiostatistics - generalfish populationqbccBiogeochemical cyclesInterpret graphsSolving Equations and InequalitiesConcepts in StatisticsElementary Hypothesis TestingMethylmercurydamsBioaccumulationtraditional dietsmercurymercury poisoningnative peopleindigenous populationCanadahydroelectricexplaining statisticsusing statisticsMake probability calculations

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    Calculating Lifetime Cancer Risk Resulting from DNA Replication
    An expanded case study adapted from an HHMI Data Point on Cell Division and Cancer Risk using Figure 1 from Tomasetti, C. and Vogelstein, B. (2015).

    Keywords: cancerScientific ProcessStatistics and MathScientific Methodologybiology of cellscell growth and divisionHigh School

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