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    Understanding COVID-19 Biology to Design a Vaccine
    This multi-part case study introduces the reader to the SARS-CoV-2 virus, replication, and treatment. Additional worksheets introduce students to bioinformatics tools of 3-D protein visualization...

    Keywords: BLASTprotein structure modelingmolecular visualization and analysisCOVID19PDB

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    Piwi Matters
    This case focuses on understanding structure and function relationships in Piwi, a protein that is critical for germline stem cell function and development of eggs in the fruit fly ovary.

    Keywords: Stem cellsmolecular visualization and analysis3D protein structure /function analysisPiwiPDBMolecular Case Study

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    Happy Blue Baby
    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved on its own...

    Keywords: mutationHemoglobinmolecular visualization and analysisPDBMolecular Case Study

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    CYTOSKELETON - Microtubule Dynamics in the Cell Cycle
    This module contains exercises designed to help upper-level cell biology students understand the dynamics of microtubule polymerization and depolymerization within the cell cycle and how cancer...

    Keywords: cell biologyQuantitative reasoningInterdisciplinary STEMInterpreting GraphsCytoskeletonScientific reasoningdimensional analysisNIQBC2. Data and GraphsC6. Quantitative LanguageC1. Numeracy

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    The Mathematics of Voting Systems: Plurality, Runoff and Ranked Choice
    In this five-day interdisciplinary math and social studies unit, students use math to create informed opinions about the three most common voting systems in the United States: plurality, runoff and...

    Keywords: mathematicsInterdisciplinary STEMInterdisciplinary Mathematics Educationinterdisciplinary math educationvoting

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    Visualization: Quantitative reasoning via image analysis, networks, topology, generative models, and 3D rendering
    Resource from the 2015 BioQUEST Summer Workshop
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    Quantitative reasoning: Interdisciplinary STEM 21st century reasoning modality
    Resource from the 2015 BioQUEST Summer Workshop

    Keywords: stemQuantitative reasoning

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    The Effect of Instructor Communication on Student Perceptions of Mathematics in Biology
    Undergraduate research poster presented at the Undergraduate Research Symposium at the University of Pittsburgh in 2015.

    Keywords: biology teachingundergraduate researchPresentation

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    Discovering Prokaryotic Gene Regulation by Building and Investigating a Computational Model of the lac Operon
    The ability to construct and reason through a biological system is an important skill to develop in science education. This level of understanding forces students to recognize the interrelatedness...

    Keywords: prokaryotesgene regulationLac Operoninducible operon

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    The Molecular CaseNet Pipeline for Authoring, Piloting, and Evaluating Molecular Case Studies
    This poster provides an overview of the pipeline for authoring, piloting, and reviewing molecular case studies for publication in Molecular CaseNet.

    Keywords: resources @ Molecular CaseNet

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    Box of Lessons: A Toolkit for Introducing Students to Biomolecular Structure and Function
    This is a poster describing a collection of open educational resources that were developed by faculty participating in the Molecular CaseNet Faculty Mentoring Network in Spring 2022. The collection...

    Keywords: bioinformaticsbiomolecular structureProtein Data Bankresources @ Molecular CaseNet

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    2014-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
    To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for...

    Keywords: metabolic syndromecompartment modelcholesterolhigh blood cholesterol

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    2015-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
    To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for...

    Keywords: metabolic syndromecholesterolhigh blood cholesterolcholesterol homeostasis

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    2013-Deboeck-Bergeman-The reservoir model-DE model of psychological regulation
    The following article describes a differential equation model based on the concept of a reservoir for psychological regulation.

    Keywords: adaptive copingReservoirsNotre Dame Longitudinal Study on Agingoutputinput distributionstressorscoping resources

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    2019-Stender_EtAl-Recovery_Of_Differential_Equations_From_Impulse_Response
    In this work, a recent method, which allows reconstructing differential equations from time series data, is extended for higher degrees of automation.

    Keywords: time seriesregressionresponseimpulseoscillationsignal processingsparse regressionsystem identification

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    5-040-TunedMassDampers-PartII-ModelingScenario
    Studentsbuild mathematical models to mitigate dangerous swaying in structures using structural improvements called Tuned Mass Dampers (TMD). We model the motion of the original structure as a...

    Keywords: structureresistancespring-mass-dashpotearthquakevibrationcontroldampingtuned mass damperstiffnessreduction of vibration

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    Urban stream invaders: a scientist spotlight featuring Dr. Piatã Santana Marques
    Students read and interpret data from a study which addresses how urbanization affects the invasive attributes of a non-native species. They also reflect on the identity of the lead researcher and...

    Keywords: ecologyInvasive SpeciesStream ecologyurban ecologynutrient pollution

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    The Happy Blue Baby Hemoglobin
    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved.

    Keywords: mutationHemoglobinmolecular visualization and analysisPDBMolecular Case Study

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    Using computational molecular modeling software to demonstrate how DNA mutations cause phenotypes
    This lesson is a five-week series of laboratory activities designed to help students transition from applying lower order thinking skills to the central dogma to applying higher-order thinking skills.

    Keywords: bioinformaticsNIBLSEProtein StructureDNAmolecular modelinggenotypephenotypeCourseSourcecomputational modelingcentral dogmaplant leaf structure

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    A STEAM Approach to Investigating the Hydrologic Cycle
    The purpose of this experiential lesson is to teach introductory to mid-level undergraduate students how to make detailed hydrologic field observations into a conceptual model using a painting...

    Keywords: modelinghydrologyfield-based learningSTEAM curriculumhydrogeologyhydrologic cycle

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