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  1. Evaluating the potential for immune escape: how likely is an antibody to protect against a specific SARS-CoV-2 variant?

    24 May 2024 | Teaching Materials | Contributor(s):

    By Allyson Sterling1, Erica Lannan2, Sandra Porter3

    1. Regis University 2. Prairie State College 3. Digital World Biology

    Commercial antibodies to the SARS-CoV-2 spike protein have been successfully used to treat people with COVID-19. Unfortunately, as the SARS-CoV-2 virus evolves, new variants have appeared that can...

    https://qubeshub.org/publications/4763/?v=1

  2. BSL-4: Authorized Personnel Only

    15 Mar 2023 | Teaching Materials | Contributor(s):

    By Nicole Anthony

    Biological Sciences, Toronto District School Board

    National Center for Case Study Teaching in Science resource on the 2014 Ebola epidemic. This resource is also included in the NIBLSE Learning Resource Collection

    https://qubeshub.org/publications/795/?v=2

  3. Colon Cancer: A Case of Genetic Bad Luck

    15 Mar 2023 | Teaching Materials | Contributor(s):

    By Anne M. Casper

    Eastern Michigan University

    Case study developed for an introductory genetics class published in the National Center for Case Study Teaching in Science

    https://qubeshub.org/publications/992/?v=2

  4. Evaluating the potential for immune escape: how likely is an antibody to protect against a specific SARS-CoV-2 variant?

    10 Jun 2022 | Teaching Materials | Contributor(s):

    By Sandra Porter1, Uwe Hilgert2, Erica Lannan3, Michelle Stieber4

    1. Digital World Biology 2. Bio5 Institute 3. Prairie State College 4. Cerritos College

    Commercial antibodies to the SARS-CoV-2 spike protein have been successfully used to treat people with COVID-19. Unfortunately, as the SARS-CoV-2 virus evolves, new variants have appeared that can...

    https://qubeshub.org/publications/2913/?v=1

  5. Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses

    28 Aug 2021 | Teaching Materials | Contributor(s):

    By Adam J. Kleinschmit*1, Benita Brink1, Steven Roof2, Carlos Christopher Goller3, Sabrina Robertson3

    1. Adams State University 2. Fairmont State University 3. North Carolina State University

    Introductory bioinformatics exercises often walk students through the use of computational tools, but often provide little understanding of what a computational tool does "under the...

    https://qubeshub.org/publications/2622/?v=1

  6. You and Your Oral Microflora: Introducing non-biology majors to their “forgotten organ”

    22 Aug 2021 | Teaching Materials | Contributor(s):

    By Anna K. Strain1, Kieng B. Vang1

    University of Minnesota

    With limited time available for laboratory activities, introductory science courses for non-science majors typically use the laboratory period to reinforce material that was previously presented...

    https://qubeshub.org/publications/2514/?v=1

  7. Inquiry-based hypothesis testing using phylogenetic trees in MEGA

    17 Jun 2021 | Teaching Materials | Contributor(s):

    By Kristin Hultgren

    Seattle University

    A key learning objective in biology is applying bioinformatics tools to test a real-life question. These inquiry-based modules have students assemble and align data, and construct simple...

    https://qubeshub.org/publications/2379/?v=1

  8. Hemoglobin bioinformatics

    07 Jun 2021 | Teaching Materials | Contributor(s):

    By Keith A. Johnson

    Bradley University College of Liberal Arts and Sciences

    This is an introduction to bioinformatics using hemoglobin as an example. The worksheets introduce students to resources to explore the DNA, RNA and polypeptide linear structure with a brief...

    https://qubeshub.org/publications/2416/?v=1

  9. Sequence Similarity: Introducing Biological Databases to Community College Biology Students

    01 Jun 2021 | Teaching Materials | Contributor(s):

    By Jennifer Katcher

    This laboratory module, published on CourseSource, leads introductory biology students in the exploration of a basic set of bioinformatics concepts and tools.

    https://qubeshub.org/publications/2407/?v=1

  10. Developing a phylogram from computational resources.

    01 Jun 2021 | Teaching Materials | Contributor(s):

    By Melanie Lenahan1, Shea Cinquemani1

    Raritan Valley Community College

    This laboratory module, published on CourseSource, leads introductory biology students in the exploration of a basic set of bioinformatics concepts and tools.

    https://qubeshub.org/publications/2404/?v=1

  11. Introductory Video and worksheets on Module 1 and 2 on "Sequence Similarity: An inquiry based and under the hood..."

    31 May 2021 | Teaching Materials | Contributor(s):

    By Alice Tarun

    St. Lawrence University

    The video walks the students to complete Module 1 and 2 on Sequence Similarly and Alignment adapted from Tapprich (2019) and Hudson Alpha that teaches these modules within the context of the...

    https://qubeshub.org/publications/2394/?v=1

  12. Yeti or not: Do they exist?

    31 Dec 2020 | Teaching Materials | Contributor(s):

    By Keith Johnson1, Adam Kleinschmit2, Jill Rulfs3, William (Bill) Morgan4

    1. Bradley University College of Liberal Arts and Sciences 2. University of Dubuque 3. Worcester Polytechnic Institute 4. The College of Wooster

    Through this 4-part bioinformatics case study, students will be led through the forensic analysis of putative Yeti artifacts based on published findings.

    https://qubeshub.org/publications/1832/?v=3

  13. A Critical Guide to BLAST

    04 Dec 2020 | Teaching Materials | Contributor(s):

    By Teresa Attwood1, GOBLET Foundation

    The University of Manchester, Manchester, UK

    This Critical Guide in the Introduction to Bioinformatics series provides an overview of the BLAST similarity search tool, briefly examining the underlying algorithm and its rise to popularity.

    https://qubeshub.org/publications/2172/?v=1

  14. BSL-4: Authorized Personnel Only

    17 Aug 2020 | Teaching Materials | Contributor(s):

    By Nicole Anthony

    Biological Sciences, Toronto District School Board

    National Center for Case Study Teaching in Science resource on the 2014 Ebola epidemic. This resource is also included in the NIBLSE Learning Resource Collection

    https://qubeshub.org/publications/795/?v=1

  15. GEA Introductory lesson on BLAST

    25 Jul 2020 | Teaching Materials | Contributor(s):

    By Justin DiAngelo1, Alexis Nagengast2, Wilson Leung3, Douglas L Chalker3

    1. Penn State Berks 2. Widener University 3. Washington University in St. Louis

    The "Introduction to BLAST using Human Leptin" exercise aims to introduce students to the use of the Basic Local Alignment Search Tool (BLAST) to identify related sequences and compare similarity...

    https://qubeshub.org/publications/1987/?v=1

  16. Making bioinformatics tools classroom-friendly

    23 Jul 2020 | Teaching Materials | Contributor(s):

    By Jason Williams, Wilson Leung1, Cornel Ghiban2

    1. Washington University in St. Louis 2. Cold Spring Harbor Laboratory

    Poster on using Cyverse resources to make classroom that make using bioinformatics in the classroom a more manageable experience presented at the 2020 BIOME Institute: Cultivating Scientific Curiosity

    https://qubeshub.org/publications/2000/?v=1

  17. Understanding COVID-19 Biology to Design a Vaccine - Ethics supplement

    08 Jul 2020 | Teaching Materials | Contributor(s):

    By Keith A. Johnson

    Bradley University College of Liberal Arts and Sciences

    The adaptation to Understanding COVID-19 Biology to Design a Vaccine entails two ethics supplements. The first supplement addresses the use of off-label drugs in the pandemic (or other situation)....

    https://qubeshub.org/publications/1955/?v=1

  18. COVID-19: On the way to a vaccine

    13 Jun 2020 | Teaching Materials | Contributor(s):

    By Nik Tsotakos

    Penn State Harrisburg

    This multi-part case study introduces the reader to the SARS-CoV-2 virus origins, the molecular basis of the infection, the development and severity of symptoms, and treatment.

    https://qubeshub.org/publications/1918/?v=1

  19. Understanding COVID-19 Biology to Design a Vaccine

    12 Jun 2020 | Teaching Materials | Contributor(s):

    By Keith Johnson1, Didem Vardar-Ulu2, Shuchismita Dutta3

    1. Bradley University College of Liberal Arts and Sciences 2. Boston University 3. RCSB Protein Data Bank, Rutgers University

    This multi-part case study introduces the reader to the SARS-CoV-2 virus, replication, and treatment. Additional worksheets introduce students to bioinformatics tools of 3-D protein visualization...

    https://qubeshub.org/publications/1904/?v=1

  20. Yeti or not: Do they exist?

    14 May 2020 | Teaching Materials | Contributor(s):

    By Keith Johnson

    Bradley University College of Liberal Arts and Sciences

    Through this 2-part bioinformatics case study, students will be led through the forensic analysis of putative Yeti artifacts based on published findings.

    https://qubeshub.org/publications/1832/?v=1

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