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Tags: splicing

All Categories (1-5 of 5)

  1. An undergraduate bioinformatics curriculum that teaches eukaryotic gene structure

    31 Aug 2021 | Teaching Materials | Contributor(s):

    By Meg M. Laakso1, Leocadia V. Paliulis2, Paula Croonquist3, Brianna Derr2, Elena Gracheva4, Charles Hauser5, Carina Howell6, Christopher Jones7, Jacob D. Kagey8, Jennifer Kennell9, S. Catherine Silver Key10, Hemlata Mistry11, Srebrenka Robic12, Jamie Sanford13, Marisol Santisteban14, Chiyedza Small15, Rebecca Spokony16, Joyce Stamm17, Melanie Van Stry18, Wilson Leung4, Sarah C.R. Elgin4

    1. Eastern University 2. Bucknell University 3. Anoka-Ramsey Community College 4. Washington University in St. Louis 5. St. Edward’s University 6. Lock Haven University 7. Moravian College 8. University of Detroit Mercy 9. Vassar College 10. North Carolina Central University 11. Widener University 12. Agnes Scott College 13. Ohio Northern University 14. The University of North Carolina at Pembroke 15. Medgar Evers College, The City University of New York 16. Baruch College, The City University of New York 17. University of Evansville 18. Lane College

    Gene structure, transcription, translation, and alternative splicing are challenging concepts for many undergraduates studying biology. These topics are typically covered in a traditional lecture...

    https://qubeshub.org/publications/2592/?v=1

  2. A Hands-on Introduction to Hidden Markov Models

    24 Aug 2021 | Teaching Materials | Contributor(s):

    By Anton E. Weisstein1, Elena Gracheva2, Zane Goodwin2, Zongtai Qi2, Wilson Leung2, Christopher D. Shaffer2, Sarah C.R. Elgin2

    1. Truman State University 2. Washington University in St. Louis

    In this Lesson, we describe a classroom activity that demonstrates how a Hidden Markov Model (HMM) is applied to predict a eukaryotic gene, focusing on predicting one exon-intron boundary. This HMM...

    https://qubeshub.org/publications/2562/?v=1

  3. Module 4: Removal of Introns from pre-mRNA by Splicing

    25 Jul 2020 | Teaching Materials | Contributor(s):

    By Meg Laakso1, Anne Rosenwald2

    1. Eastern University 2. Georgetown University

    In this module, students will learn to identify splice donor and acceptor sites that are best supported by RNA-Seq data, and use the canonical splice donor and splice acceptor sequences to identify...

    https://qubeshub.org/publications/1992/?v=1

  4. Module 3: Transcription, Part II: What Happens to the Initial Transcript Made by RNA pol II?

    25 Jul 2020 | Teaching Materials | Contributor(s):

    By Cathy Silver Key1, Chiyedza Small2, Laura Reed3

    1. North Carolina Central University 2. Medgar Evers College CUNY 3. The University of Alabama

    This module teaches about the three key steps that are involved in converting the pre-mRNA into a mature mRNA: 1) The addition of a 5’ cap, 2) The addition of a 3’ poly(A) tail, 3) The removal of...

    https://qubeshub.org/publications/1991/?v=1

  5. A Hands-on Introduction to Hidden Markov Models

    04 Jan 2019 | Teaching Materials | Contributor(s):

    By Tony Weisstein1, Elena Gracheva2, Zane Goodwin2, Zongtai Qi2, Wilson Leung2, Christopher D. Shaffer2, Sarah C.R. Elgin2

    1. Truman State University 2. Washington University in St. Louis

    A lesson in which students will understand the basic structure of an HMM, the types of data used in ab initio gene prediction, and its consequent limitations.

    https://qubeshub.org/publications/999/?v=1