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    Advanced Student Molecular Case Study Authorship Scaffolded Project and Rubric
    Instructions, assignment prompts, and a rubric for assessing advanced undergraduate authorship of molecular case studies
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    Collaborative case writing and field testing with Molecular CaseNet brings together discipline specific expertise for innovative pedagogical tools in the classroom
    Molecular case studies (MCS) use an interesting story as a hook , followed by exploration of biochemistry of one or more molecules of interest.  They can be useful in teaching about macromolecule...
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    Happy Blue Baby
    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved on its own...

    Keywords: mutationHemoglobinmolecular visualization and analysisgenetic basisPDBMolecular Case StudyMol*

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    CRISPR Gene Editing: Designing the gRNA and Donor Template
    In this adaptation, students learn how CRISPR/Cas9 is used in bacterial immunity and gene editing. Students create both a gRNA target and a donor template to edit a gene. Mutations can be from the...

    Keywords: geneticseducationcell biologymolecular biologymutationStem cellsstructure-functionmolecular visualization and analysis3D protein structure /function analysisCRISPR/Cas9crisprDNA mutationPiwiPDBMolecular Case StudyPiwi Matters

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    Molecular Basis of Sickle Cell Disease
    This multi part case on hemoglobin structure as it relates to oxygen binding and sickle cell disease focuses on utilizing bioinformatics and molecular visualization tools to learn about the sickle...

    Keywords: Hemoglobinmolecular visualization and analysisintroductory bioinformaticssickle cell diseasePDBMolecular Case Studyoxygen bindingmyoglobinmolecular literacy3D protein structuresstructural representations

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    SKILLS DEVELOPMENT - Toxicology MSDT
    On this website you can find 6 learning modules on various topics in toxicology. These are self-paced student-centered online learning modules. You will receive a certificate of completion at the...

    Keywords: pathophysiologyregulatory toxicologyprinciples of toxicologybiochemistry and molecular geneticsprinciples of genetic toxicologyapplied systems toxicology

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    COVID-19: On the way to a vaccine
    This multi-part case study introduces the reader to the SARS-CoV-2 virus origins, the molecular basis of the infection, the development and severity of symptoms, and treatment.

    Keywords: BLASTprotein structure modelingmolecular visualization and analysisCOVID19PDB

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    Drugging SARS-CoV-2
    This case study leads students through the process of proposing a drug for a novel protein. The Mpro protease of SARS-CoV-2 is explored in detail within the PDB. Aligns with first semester...

    Keywords: viruscoronavirusPDBSARS-CoV-2proteasedrug design

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    Understanding COVID-19 Biology to Design a Vaccine
    This multi-part case study introduces the reader to the SARS-CoV-2 virus, replication, and treatment. Additional worksheets introduce students to bioinformatics tools of 3-D protein visualization...

    Keywords: BLASTprotein structure modelingmolecular visualization and analysisCOVID19PDB

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    Bacteria to Brains in Backyard Coyotes: An Interdisciplinary Pedagogical Case Study
    Our interdisciplinary pedagogical case study explores the differences between rural and urban coyotes at the levels of organismal and community ecology. The focus is on how coyotes’ gut microbiomes...

    Keywords: Vision and Changeecologyintroductory biologyImmunologymicrobiologydietanimal behaviormicrobiomecore conceptscoyotesBraingut-brain axisImmunoReachcytokinedysbiosis

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    Hemoglobin bioinformatics
    This is an introduction to bioinformatics using hemoglobin as an example. The worksheets introduce students to resources to explore the DNA, RNA and polypeptide linear structure with a brief...

    Keywords: bioinformaticsHemoglobinBLASTsickle cell diseaseMolecular Case StudyClustal OmegaMolCaseNet

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    Managing Prairie Dogs for Ferret Reintroduction: A Case Study in an online environment
    The case study Managing Prairie Dogs for Ferret Reintroduction was modified to be used in an online environment.
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    Venom: To Kill or Cure?
    In this case study, students will explore concepts of evolution, protein structure and function, taxonomy, and methods of scientific inquiry in a real-world way.

    Keywords: EvolutionphylogeneticsidigbioAP Biologytaxonomynatural history collections3D modelsoVertVenomsnakesherps

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    Calling Bull Case Study — 99.9% Caffeine-free with R
    This is an adaptation of Calling Bull's Case Study on how caffeine free is hot chocolate versus coffee in order to make it into a student project that uses R.

    Keywords: Rcase studyRStudiointroductionPercentagescalling bullstoichiometrycaffienescripts

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    Case Study: Genetic Variation and Speciation in the Black Tailed Rattlesnake complex (Crotalus molossus)
    It is important for biology students to understand how genetic variation is related to the formation of species in nature. This module is intended for students to obtain first hand experience with...

    Keywords: phylogeneticscase studySpeciationtree readingsystematicsTree thinkingPhylogeographydistance learninggenetic variation

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    Yeti or not: Do they exist?
    Through this 4-part bioinformatics case study, students will be led through the forensic analysis of putative Yeti artifacts based on published findings.

    Keywords: case studybioinformaticsNIBLSEBLAST12S sequencingYeti

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    The Legacy of Redlining in Oakland, CA
    The issues of redlining and environmental justice will be introduced and used as a framework for a number of topics in the third part of the semester in a non-majors Environmental Science course.

    Keywords: environmental scienceenvironmental justiceredliningenvironmental racism

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    Modeling Trophic Interactions in Rice Agriculture: A Jigsaw Approach
    Students explore four different issues related to trophic interactions that affect modern rice agriculture practices and consider relationships between these issues using Lotka and Volterra...

    Keywords: mathematical modelLotka-Volterrajigsawfood chaintrophic cascadespredator-prey interactionsfood web

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    Understanding Trophic Interactions in Rice Agriculture: A Jigsaw Approach
    Students explore four different issues related to trophic interactions that affect modern rice agriculture practices and consider relationships between these issues.

    Keywords: jigsawfood chaintrophic cascadesfood web

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    Conservation and ethics of using synthetic genetics
    This contains teaching material - powerpoints and handouts that can be adapted for lectures and/or discussion groups.
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