QUBES will have scheduled maintenance work beginning on Wednesday, June 26, 2024, 4pm ET/1pm PT. The platform will operate normally for most of the day, except for an extended outage period lasting no more than 4 hours. All running tool sessions will expire during the maintenance window. Please plan accordingly and we do apologize for any inconvenience. close

You are here: Home / Resources / Browse Resources

Open. Adaptable. Free.

Resources created by our members and partners.

The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

Text Search:
Applied Filters
    Cancer Discovery Activities
    These two hands-on activities are based on a Howard Hughes Medical Institute 2013 Holiday Lectures on Science video (http://www.hhmi.org/biointeractive/cancer-genetic-disease-video-highlights)...

    Keywords: geneticsResources @ HHMI - BioInteractiveorganismal biologyneurosciencegenomicscancergenetic basis of diseasebiology of cellsHigh School

    1803

    views

    309

    downloads

    0

    comments

    2

    adaptations

    Calculating Lifetime Cancer Risk Resulting from DNA Replication
    An expanded case study adapted from an HHMI Data Point on Cell Division and Cancer Risk using Figure 1 from Tomasetti, C. and Vogelstein, B. (2015).

    Keywords: cancerScientific ProcessStatistics and MathScientific Methodologybiology of cellscell growth and divisionHigh School

    1374

    views

    1003

    downloads

    0

    comments

    0

    adaptations

    Cell Division and Cancer Risk Data Point
    Cancer is typically attributed to hereditary and environmental factors, but these only explain a fraction of overall cancer risk. This activity explores a third factor.

    Keywords: Resources @ HHMI - BioInteractivecancerScientific ProcessStatistics and MathScientific Methodologybiology of cellscell growth and divisionHigh School

    2487

    views

    340

    downloads

    0

    comments

    1

    adaptations

    2018-Dyjuan_Tatro-The_Mathematics_of_Cancer-Fitting_Gompertz_Equation_to_Tumor_Growth
    Fitting the Gompertz Model to long term breast cancer study data, this project ascertains gompertzian parameters that can be used to predicts tumor growth as a function of time.

    Keywords: tumorgrowthGompertzfittingparameter

    114

    views

    44

    downloads

    0

    comments

    0

    adaptations

    The p53 Gene and Cancer
    This tutorial describes the structure and function of the p53 protein, how its activity is regulated in cells, and how mutant versions of p53 can lead to cancer.

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymolecular biologymacromoleculesGenetic disease

    3240

    views

    416

    downloads

    0

    comments

    1

    adaptations

    Using Nanoparticles to Treat Cancer Scientist Spotlight
    Students use published scientific data to determine which types of nanoparticles would be best to use to deliver cytotoxic drugs directly to cancer cells. Then they learn about the scientist who...

    Keywords: cancer biologyscientist spotlightsnanoparticles

    1041

    views

    372

    downloads

    0

    comments

    0

    adaptations

    Drug screening and cancer resistance: EGFR Activity
    This activity explores a specific gene (egfr) and its role in cancer. EGFR was introduced with the Gene Card Activities, researched throughout the semester, and then authentic image data of...

    Keywords: Resources @ HHMI - BioInteractivegenomicscancergenetic basis of diseasebiology of cells

    1250

    views

    1330

    downloads

    0

    comments

    0

    adaptations

    3D breast cancer tissue reconstruction
    This module allows students to follow a researcher as she discovers new features of breast cancer tissue architecture, using 3D reconstructions of histological specimens.

    Keywords: graphingdata visualizationbreast cancerDCIShistogramscentroidsums of squares

    2135

    views

    1618

    downloads

    0

    comments

    0

    adaptations

    GMC: Genes, Mutations and Cancer - Group Concept Map Development
    It has been shown that active learning strategies used in the classroom can increase student learning and retention of information. We generated an active learning exercise that can be used in the...

    Keywords: mutationcancerCell Division

    2587

    views

    443

    downloads

    0

    comments

    0

    adaptations

    Teaching Cancer Biology Through a Lens of Social Justice
    The biology classroom is not separate from the greater context of society; social issues can and should be presented in connection with the content. Here we present an example of antiracist...

    Keywords: assessmentcancersocial justicePOGILAlignmentPublic ExamPublic

    4455

    views

    670

    downloads

    0

    comments

    0

    adaptations

    Why do Some People Inherit a Predisposition to Cancer? A small group activity on cancer genetics
    Before undergraduate students take a genetics course they generally know cancer has a genetic basis and involves the proliferation of cells; however, many are uncertain about why only a subset of...

    Keywords: cancerInheritance patternsProbability calculationProto-oncogeneTumor Suppressor Gene

    1701

    views

    433

    downloads

    0

    comments

    0

    adaptations

    Building a Model of Tumorigenesis: A small group activity for a cancer biology/cell biology course
    The multistep nature of tumorigenesis is a foundational concept in the context of Cancer Biology. Many students do not appreciate the complex nature of cancer development nor do they understand how...

    Keywords: pathwayscancerMolecular AlterationsRetrospective dataTumorigenesis

    1322

    views

    493

    downloads

    0

    comments

    0

    adaptations

    CYTOSKELETON - Microtubule Dynamics in the Cell Cycle
    This module contains exercises designed to help upper-level cell biology students understand the dynamics of microtubule polymerization and depolymerization within the cell cycle and how cancer...

    Keywords: cell biologyQuantitative reasoningInterdisciplinary STEMInterpreting GraphsCytoskeletonScientific reasoningdimensional analysisNIQBC2. Data and GraphsC6. Quantitative LanguageC1. Numeracy

    407

    views

    222

    downloads

    0

    comments

    0

    adaptations

    2020-Stepien_Kostelich_Kuang-Mathematics Cancer An Undergraduate Bridge Course in Applied Mathematics
    Most undergraduates have limited experience with mathematical modeling. This paper describes a course on the mathematical models of cancer growth and treatment.

    Keywords: differential equationsmodelingundergraduate educationcancertumor

    209

    views

    49

    downloads

    0

    comments

    0

    adaptations

    3D breast cancer tissue reconstruction image files
    Database of image files for AIMS Resource: 3D breast cancer tissue reconstruction

    Keywords: Resources @ AIMS

    1007

    views

    127

    downloads

    0

    comments

    0

    adaptations

    2015-Heiko_Enderling-Integrating experimental data to calibrate quantitative cancer models
    For quantitative cancer models to be meaningful and interpretable the number of unknown parameters must be kept minimal. We focus on a tumor hierarchy of cancer stem and progenitor non-stem cancer...

    Keywords: cancertumorfittingagent-based

    108

    views

    81

    downloads

    0

    comments

    0

    adaptations

    Metastatic Mastery: A Case and Game-Based Approach to Learning About Cancer Mechanisms
    Mechanisms that contribute to the development of cancer are numerous and complicated, though most can be traced to a set of mutations in cell cycle regulatory genes that throw the process of cell...

    Keywords: mutationcancertranscriptioncell cycletranslationOncogenesTumor-suppressorp53Transcription factor

    1866

    views

    362

    downloads

    0

    comments

    0

    adaptations

    Cell Division and Rates of Population Growth
    This module introduces the exponential growth of cells in the context of understanding cell division. It is intended for an introductory biology audience.

    Keywords: exponential equationscell growth and divisionGeometric SeriesCell StructureOpenStaxgeometric equations

    1049

    views

    189

    downloads

    0

    comments

    0

    adaptations

    Doubling Time of Tumors
    This module introduces the calculation of potential doubling time of tumorous cells in the context of understanding the growth of a population of the cells. It is intended for an introductory...

    Keywords: linear regressionRatiosCell StructureOpenStaxCell Growth

    916

    views

    167

    downloads

    0

    comments

    0

    adaptations

    Data Analysis and Cancer
    This is a flipped classroom approach, students will learn the basic content about cell-signaling, p53, and transcription factors before class. During class students will focus on data analysis...

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymolecular biologydata interpretationBiological Data Analysiscell cyclemacromoleculesGenetic diseaseCell signaling

    1612

    views

    3716

    downloads

    0

    comments

    0

    adaptations

    Close

    Home

    Search