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    Module 5: The Need for an Open Reading Frame
    In this module, students will learn to identify the open reading frames for a given gene, and define the phases of the splice donor and acceptor sites.
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    Module 4: Removal of Introns from pre-mRNA by Splicing
    In this module, students will learn to identify splice donor and acceptor sites that are best supported by RNA-Seq data, and use the canonical splice donor and splice acceptor sequences to identify...
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    Module 3: Transcription, Part II: What Happens to the Initial Transcript Made by RNA pol II?
    This module teaches about the three key steps that are involved in converting the pre-mRNA into a mature mRNA: 1) The addition of a 5’ cap, 2) The addition of a 3’ poly(A) tail, 3) The removal of...
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    Exploring Population Change without Selection: Avida-Ed Lab Book Exercise 4
    An introductory activity exploring how a population changes without natural selection using the Avida-ED simulation.
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    Exploring Fitness and Population Change under Selection: Avida-Ed Lab Book Exercise 3
    An introductory activity exploring the process of natural selection in action using the Avida-ED simulation.
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    Exploring the Introduction of Genetic Variation by Random Mutation: Avida-Ed Lab Book Exercise 1
    An introductory activity introducing the role of random mutation in generating genetic variation using the Avida-ED simulation.
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    Louse Genetics, Genomics, and Gene Function...Oh My!
    In this module, students will be investigating a louse gene with an unknown function to determine if it might be important in the evolution of the louse ecomorphs.
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    Intro videos and terminology for GMOs, Transcription, Translation
    Compiled resources around GMOs and protein production including vocabulary, animations, videos, and games
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    Hardy-Weinberg Equilibrium
    This module introduces the Hardy-Weinberg model in the context of understanding the population's genotype and allele frequencies. It is intended for an introductory biology audience.
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    The Chi-Square Test
    This module introduces how to determine whether observation is significantly different from expectation in the context of understanding Chi-square Test. It is intended for an introductory biology...
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    Exploration of the Human Genome by Investigation of Personalized SNPs
    To increase students' interest in their own genomes, this computer-based laboratory lesson is designed to be coupled with the opportunity for the students to be genotyped by the consumer sequencing...
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    Birthday Problem and Class Phenotypic Probabilities
    An Excel workbook exploring two related applications, the Birthday Problem and Class Phenotypic Probabilities. Students enter their own phenotypes into the workbook.
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    ABO Blood Group Frequencies
    An Excel workbook in which students can calculate blood type frequencies through different approaches (Hardy-Weinberg, quadratic formula, and the EM algorithm). The workbook shows the formulas...
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    Chi-Square analysis of two point test cross data
    This flash tutorial simulates analysis of a 2 point test cross and will walk you through the analysis of two hypothetical traits.
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    Monkey Opsins
    This case will examine the evolution of trichromatic vision in old world monkeys.
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    Cancer Discovery Activities
    These two hands-on activities are based on a Howard Hughes Medical Institute 2013 Holiday Lectures on Science video (http://www.hhmi.org/biointeractive/cancer-genetic-disease-video-highlights)...
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    Why do Some People Inherit a Predisposition to Cancer? A small group activity on cancer genetics
    Before undergraduate students take a genetics course they generally know cancer has a genetic basis and involves the proliferation of cells; however, many are uncertain about why only a subset of...
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    Fruit Fly Genetics in a Day: A Guided Exploration to Help Many Large Sections of Beginning Students Uncover the Secrets of Sex-linked Inheritance
    Moving beyond the basic concepts of autosomal Mendelian inheritance to sex-linkage can be difficult for introductory biology students. Although crosses with Drosophila fruit flies have long been a...
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    Mapping a Mutation to its Gene: The "Fly Lab" as a Modern Research Experience
    Although genetics is an invaluable part of the undergraduate biology curriculum, it can be intimidating to students as well as instructors: Students must reduce their reliance on memorization and...
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    Fragile States: A Case Study Exploring Genetics, Molecular Biology, and Biochemistry Through the Lens of Fragile X Syndrome
    This case aims to strengthen students’ understanding of molecular biology concepts through study of Fragile X Syndrome (FXS). Students begin by learning the cause and phenotypes of FXS and...
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