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    Collaborative case writing and field testing with Molecular CaseNet brings together discipline specific expertise for innovative pedagogical tools in the classroom
    Molecular case studies (MCS) use an interesting story as a hook , followed by exploration of biochemistry of one or more molecules of interest.  They can be useful in teaching about macromolecule...
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    Understanding COVID-19 Biology to Design a Vaccine - Ethics supplement
    The adaptation to Understanding COVID-19 Biology to Design a Vaccine entails two ethics supplements. The first supplement addresses the use of off-label drugs in the pandemic (or other situation)....

    Keywords: bioethicsBLASTprotein structure modelingmolecular visualization and analysisethicsCOVID19PDB

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    Sickle Cell Anemia using Nicholas’ Story
    The goal of this exercise is to introduce students to 3-D structures of biological molecules, visualize and manipulate them to understand their functions. The exercise also helps them see the...

    Keywords: Hemoglobinsickle cell diseaseMolecular Case Study

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    Hemoglobin Evolution
    This module introduces equations describing blood viscosity and oxygen transport in the context of understanding the evolution of red blood cells. It is intended for an introductory biology audience.

    Keywords: calculushyperbolic equationsAnimal Physiologyparabolic equationsmaxima

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    Molecular Biology of the Cell (MBoC)
    An online journal focusing upon generally-applicable studies of cell biology.

    Keywords: cell biologycellmolecular biologyResources @ ASCBResources @ QUBES - Teaching & Reference

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    A Case of Severe Insulin Resistance
    This case focuses on understanding how a mutation in a cell signalling protein (a kinase) can prevent insulin function and lead to diabetes.

    Keywords: molecular visualization and analysisPDBMolecular Case Studyinsulin resistance

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    Engaging Students in Pharmacogenetics: Patient Case Studies Using the PharmGKB Website
    Cytochrome P450 (CYP) enzymes are important regulators of drug efficacy and toxicity. Genetic variation in CYP isoforms can impact how well patients respond to medications or experience unwanted...

    Keywords: toxicologyPharmacologydrug metabolismpharmacodynamicspharmacogenetics

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    Box of Lessons: A Toolkit for Introducing Students to Biomolecular Structure and Function
    This is a poster describing a collection of open educational resources that were developed by faculty participating in the Molecular CaseNet Faculty Mentoring Network in Spring 2022. The collection...

    Keywords: bioinformaticsbiomolecular structureProtein Data Bankresources @ Molecular CaseNet

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    Waking up Anna - Adaptations and Conversion to Mol*
    This case focuses on understanding the molecular basis of Anna's sleeping disorder and its treatment. The adaptations addressed question clarity and reformatting to use Mol*.

    Keywords: sleepmolecular visualization and analysisPDBMolecular Case StudyGABAMolCaseNetMol*MolStarProtein visualizationFlumazenil

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    The Happy Blue Baby Hemoglobin
    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved.

    Keywords: mutationHemoglobinmolecular visualization and analysisPDBMolecular Case Study

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    BioMolViz - Development of an Inclusive Community for the Instruction of Visualizing Biomolecules (RCN-Introduction)
    BioMolViz is a community dedicated to advancing biomolecular visualization education. We provide training, teaching tools and validated visual literacy assessments. The BioMolViz Library—our online...

    Keywords: RCN-UBE Introduction

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    Using Open-Source Bioinformatics and Visualization Tools to Explore the Structure and Function of SARS-CoV-2 Spike Protein
    The relationship between protein structure and function is a foundational concept in undergraduate biochemistry. We find this theme is best presented with assignments that encourage exploration and...

    Keywords: bioinformaticsmolecular modelingCOVID19protein structure and functionUCSF ChimeraSARS-CoV-2 spike proteinACE2 receptor

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    A "Box of Lessons" for Exploring Biomolecular Structure and Function
    Biomolecular structure and function is emphasized as a core concept in a variety of community determined educational standards for biology and chemistry. Most curricula introduce students to the...

    Keywords: bioinformaticsproteinsRNADNAmolecular visualizationbiomolecular structurebiomolecular visualizationProtein Data BankPDBMolecular CaseNet FMN

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    Mol* Adaptation: Case of Severe Insulin Resistance
    This is an adaptation using Mol* on the original case written. This case focuses on understanding how a mutation in a cell signalling protein (a kinase) can prevent insulin function and lead to...

    Keywords: molecular visualization and analysisPDBMolecular Case Studyinsulin resistanceMol*MolStar

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    Understanding COVID-19 Biology to Design a Vaccine
    This multi-part case study introduces the reader to the SARS-CoV-2 virus, replication, and treatment. Additional worksheets introduce students to bioinformatics tools of 3-D protein visualization...

    Keywords: BLASTprotein structure modelingmolecular visualization and analysisCOVID19PDB

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    Evolution of Caffeine Biosynthesis Enzymes
    This case focuses on exploring why plants make secondary metabolites like caffeine and how the enzymes required for making caffeine evolved.

    Keywords: Evolutioncaffeinemolecular visualization and analysisenzymesPDBMolecular Case Study

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    Phylogeny of Land Plants
    In this lab, students review the characteristics of the major land plant lineages. Then they perform phylogenetic analyses based on morphological characters.

    Keywords: morphologyphylogenylaboratoryplantsmolecular analysis

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    ICABL: An Inclusive Community for the Assessment of Biochemistry and Molecular Biology (BMB) Learning (RCN-UBE Introduction)
    ICABL is an inclusive and collaborative community that supports the professional development of biochemistry and molecular biology scientist-educators committed to the enhancement of student...

    Keywords: RCN-UBE Introduction

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    2012-Brian_Ingalls-Mathematical Modelling in Systems Biology An Introduction
    This is a comprehensive text with much biology background to motivate the mathematical modeling, exercises and answers, and many rich examples.

    Keywords: spatialsensitivity analysisgene regulatory networksstochasticbifurcationmetabolic networkselectrophysiologytransductionrate lawsbiochemical reactions

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    Studying phylogeny by producing phylogenetic trees of primates using morphological and molecular characteristics.
    An assignment constructing phylogenetic trees using shared, derived morphological traits and molecular differences among 18 primate species and two outlier species has been developed. Skull and...
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