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C4. Use bioinformatics tools to examine complex biological problems in evolution, information flow, and other important areas of biology. This competency is written broadly so as to encompass a variety of problems that can be addressed using bioinformatics tools, such as understanding the evolutionary underpinnings of sequence comparison and homology detection; distinguishing between genomic sequences, RNA sequences, and protein sequences; and
23 interpreting phylogenetic trees. “Complex” biological problems require that students should be able to work through a problem with multiple steps, not just perform isolated tasks.
BSL-4: Authorized Personnel Only
17 Aug 2020 | Teaching Materials | Contributor(s):
By Nicole Anthony
Biological Sciences, Toronto District School Board
National Center for Case Study Teaching in Science resource on the 2014 Ebola epidemic. This resource is also included in the NIBLSE Learning Resource Collection
Yeti or not: Do they exist?
14 May 2020 | Teaching Materials | Contributor(s):
By Keith Johnson
Bradley University College of Liberal Arts and Sciences
Through this 2-part bioinformatics case study, students will be led through the forensic analysis of putative Yeti artifacts based on published findings.
Genome Solver: Complete Set of Lessons
23 Oct 2019 | Teaching Materials | Contributor(s):
By Anne Rosenwald1, Gaurav Arora2, Vinayak Mathur3
1. Georgetown University 2. Gallaudet University 3. Cabrini University
The Genome Solver Project began as a way to teach faculty some basic skills in bioinformatics - no coding or scripting. These Lessons also work well in the undergraduate classroom, culminating with...
Using Synthetic Biology to Teach Data Science
26 Jun 2019 | Teaching Materials | Contributor(s):
By Margaret S Saha1, Beteel Abu-Ageel1, Sanjana Challa1, Xiangyi Fang1, Chai Hibbert1, Anna Isler1, Elias Nafziger1, Adam Oliver1, Hanqiu Peng1, Julia Urban1, Vivian Zhu1
College of William and Mary
Abstract for poster on using synthetic biology to introduce students to meaningful data mining, analysis, and application to engineering novel biological constructs.
A Fun Introductory Command Line Exercise: Next Generation Sequencing Quality Analysis with Emoji!
07 Jun 2019 | Teaching Materials | Contributor(s):
By Rachael St. Jacques1, Max Maza1, Sabrina Robertson2, Guoqing Lu3, Andrew Lonsdale4, Ray A Enke5
1. Department of Biology, James Madison University 2. Department of Psychology & Neuroscience, University of North Carolina at Chapel Hill 3. Department of Biology and School of Interdisciplinary Informatics, University of Nebraska Omaha 4. ARC Centre of Excellence in Plant Cell Walls, Melbourne University 5. James Madison University
This resource is a fun computer-based intro to command line programming. The activity takes FASTQ NGS data files and runs a fun program called FASTQE.
Bioinformatics: Investigating Sequence Similarity - A Plant Biology Approach
29 May 2019 | Teaching Materials | Contributor(s):
By Ami Erickson
This laboratory module is a modification of the original published on CourseSource with a focus on plant biology. In the final activity, students conduct a BLAST to compare histone protein...
Sequence Similarity Resource Adaptation: Exploring Ebola Virus
16 May 2019 | Teaching Materials | Contributor(s):
By William Tapprich
University of Nebraska-Omaha
This adaptation of the sequence similarity resource provides biology students with a basic set of bioinformatics concepts and tools. These concepts and tools are used to explore relationships...
Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses
02 May 2019 | Teaching Materials | Contributor(s):
By Adam Kleinschmit1, Benita Brink1, Steven Roof2, Carlos Christopher Goller3, Sabrina Robertson3
1. Adams State University 2. Fairmont State University 3. North Carolina State University
This laboratory module, published on CourseSource, leads introductory biology students in the exploration of a basic set of bioinformatics concepts and tools.
28 Feb 2019 | Teaching Materials | Contributor(s):
Using Undergraduate Molecular Biology Labs to Discover Targets of miRNAs in Humans
04 Jan 2019 | Teaching Materials | Contributor(s):
By Adam Idica1, Jordan Thompson1, Irene Munk Pedersen1, Pavan Kadandale1
University of California, Irvine
In this lesson, we describe an easily adaptable lab module that can be used in existing undergraduate molecular biology lab courses to conduct authentic scientific research, published in CourseSource
Using computational molecular modeling software to demonstrate how DNA mutations cause phenotypes
By Tara Phelps-Durr
This lesson is a five-week series of laboratory activities designed to help students transition from applying lower order thinking skills to the central dogma to applying higher-order thinking skills.
Teaching RNAseq at Undergraduate Institutions: A tutorial and R package from the Genome Consortium for Active Teaching
By Mark Phillip Peterson1, Jacob T Malloy2, Vincent P Buonaccorsi2, James H Marden3
1. Viterbo University 2. Juniata College 3. Pennsylvania State University
This lesson plan was created to teach RNAseq analysis as a part of GCAT-SEEK network. It is provided here, both in finished form and with the modifiable source code, to allow flexible adaptation to...
Murder by HIV? Undergraduate edition
By Naowarat (Ann) Cheeptham1, Laura B. Regassa2, Michèle I. Shuster3
1. Thompson Rivers University 2. Georgia Southern University 3. New Mexico State University
Bioinformatics case study focusing on phylogenetic tree interpretation, published in the National Center for Case Study Teaching in Science
Homologous chromosomes? Exploring human sex chromosomes, sex determination and sex reversal using bioinformatics approaches
By Kelsey Metzger
University of Minnesota, Rochester
In this four- part guided activity, students will learn about the structure and function of human autosomal and sex chromosomes, view and interpret gene maps, and gain familiarity with basic...
Finding Selection in All the Right Places
03 Jan 2019 | Teaching Materials | Contributor(s):
By Juliet F. K. Noor, Mohamed A. F. Noor
Lab introducing students to evolutionary genetics using bioinformatics and biocuration, published as GSA Learning Resource
Colon Cancer: A Case of Genetic Bad Luck
By Anne M. Casper
Eastern Michigan University
Case study developed for an introductory genetics class published in the National Center for Case Study Teaching in Science
Bioinformatics / Neuroinformatics
By William Grisham
University of California, Los Angeles
This module is a computer-based introduction to bioinformatics resources. This easy-to-adopt module weaves together several important bioinformatic tools so students can grasp how each is used in...
Bioinformatics: An Interactive Introduction to NCBI
By Seth Bordenstein
Marine Biological Laboratory
Modules showing how the NCBI database classifies and organizes information on DNA sequences, evolutionary relationships, and scientific publications. And a module working to identify a nucleotide...
Behavioral Genetics: Investigating the genes of a complex phenotype in fruit flies
By Craig E. Stanley, Jr., Charles Hadley S. King, IV, Michelle Thornton, Rob J. Kulathinal
Introductory genetics laboratory published as GSA Learning Resource
The Ames Test
By Nathan Goodson-Gregg, Elizabeth A. De Stasio
Introduction to the Ames Test, published as GSA Learning Resource