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    You and Your Oral Microflora: Introducing non-biology majors to their “forgotten organ”
    With limited time available for laboratory activities, introductory science courses for non-science majors typically use the laboratory period to reinforce material that was previously presented...

    Keywords: bacteriamicrobiomeBLASTmicrobesDNA replicationPolymerase chain reaction (PCR)

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    Homologous chromosomes? Exploring human sex chromosomes, sex determination and sex reversal using bioinformatics approaches
    Constructing a robust understanding of homologous chromosomes, sex chromosomes, and the particulate nature of genes is a notoriously difficult task for undergraduate biology students. In this...

    Keywords: bioinformaticsautosomehomologous chromosomeshomologous recombinationsex chromosomesex determinationsex reversal mutations

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    Statistics with epidemiology of COVID-19
    Introduction into heat maps, non-parametric t-test and GIF (optional) in R using an original dataset on COVID-19 infections from different counties of New Jersey, USA. Suitable for students who...

    Keywords: Rundergraduate educationheat mapsCOVID19coronavirusSARS-CoV-2GIF

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    Hemoglobin bioinformatics
    This is an introduction to bioinformatics using hemoglobin as an example. The worksheets introduce students to resources to explore the DNA, RNA and polypeptide linear structure with a brief...

    Keywords: bioinformaticsHemoglobinBLASTsickle cell diseaseMolecular Case StudyClustal OmegaMolCaseNet

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    The Human Microbiome Biodiversity in Health and Disease
    The students will analyze the human gut and vaginal microbiomes in healthy and diseased states using diversity of bacteria as determined by 16SrRNA sequence.
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    Genomics Lessons with GEA - RNA-Seq CURES
    Our BIOME Group worked towards developing a set of learning goals for faculty who plan to launch a CURE based on RNA-Seq data. We also developed a workflow for analysis of either prokaryotic or...
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    Module 6: Alternative Splicing
    This module explores how multiple different mRNAs and polypeptides can be encoded by the same gene. After completing this module students will be able to explain how alternative splicing of a gene...

    Keywords: geneticsdata visualizationmolecular biologygenomicsexonintronalternative splicingSimilarity searchesMessenger RNA

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    Module 5: The Need for an Open Reading Frame
    In this module, students will learn to identify the open reading frames for a given gene, and define the phases of the splice donor and acceptor sites.

    Keywords: geneticsamino acidsmolecular biologyGenome BrowsergenomicsAssociated Protein Synthesis FactorsCodonMessenger RNARibosomestRNAs

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    Module 4: Removal of Introns from pre-mRNA by Splicing
    In this module, students will learn to identify splice donor and acceptor sites that are best supported by RNA-Seq data, and use the canonical splice donor and splice acceptor sequences to identify...

    Keywords: geneticsdata visualizationmolecular biologygenomicsexonintronsplicingSimilarity searchesRNA Maturation

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    Module 3: Transcription, Part II: What Happens to the Initial Transcript Made by RNA pol II?
    This module teaches about the three key steps that are involved in converting the pre-mRNA into a mature mRNA: 1) The addition of a 5’ cap, 2) The addition of a 3’ poly(A) tail, 3) The removal of...

    Keywords: geneticsmolecular biologyGenome BrowsergenomicssplicingmRNAcDNA5' Cap3' Poly(A) TailRNA Maturation

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    Module 2: Transcription Part I: From DNA Sequence to Transcription Unit
    This module illustrates how a primary transcript (pre-mRNA) is synthesized using a DNA molecule as the template. Students will learn about the importance of the 5' and 3' regions of the gene for...

    Keywords: data visualizationmolecular biologybioinformaticsGenome BrowsergenomicsTranscription InitiationTranscription Start SiteTranscription Termination Signal

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    GEA Introductory lesson on RNA-Seq
    This RNA-Seq lesson uses the CyVerse VICE Platform and Jupyter notebooks to examine the expression of the leptin gene in samples from a mouse experimental design evaluating diet (high-fat vs....

    Keywords: data sciencebioinformaticsGenome BrowserRNAseqhigh throughput sequencingmRNAAlignmentNCBI Sequence Read Archive

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    Using genome browsers constructed by G-OnRamp to provide students with a Course-based Undergraduate Research Experience in genome annotation
    G-OnRamp (http://g-onramp.org) provides an easy-to-use web platform for educators to create genome browsers to engage undergraduate students in research projects, both collaborative annotation of...
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    Making bioinformatics tools classroom-friendly
    Poster on using Cyverse resources to make classroom that make using bioinformatics in the classroom a more manageable experience presented at the 2020 BIOME Institute: Cultivating Scientific Curiosity

    Keywords: bioinformaticsJupyterJupyter notebookBLASTCyVerseRNA sequencing

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    Piwi Matters
    This case focuses on understanding structure and function relationships in Piwi, a protein that is critical for germline stem cell function and development of eggs in the fruit fly ovary.

    Keywords: Stem cellsmolecular visualization and analysis3D protein structure /function analysisPiwiPDBMolecular Case Study

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    Building creatures with the central dogma of biology
    Activity that demonstrates how nucleotide changes can affect phenotypes

    Keywords: amino acidsnucleotidesRNADNAgenotypephenotypecentral dogma

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    REMNet Tutorial, R Part 2: Importing Your Microbiome Data into R 5.3.19
    Video on importing data into R from the Research Experiences in Microbiomes Network

    Keywords: growth mindsetVideoMicrobiology EducationR programming languagemicrobiomesmath attitudesResources @ BIOMAAPmistakesvalue of mistakesresearch in the classroomREMNeturban microbiomes

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    REMNet Tutorial, Excel Part 3: Organizing Your Microbiome Data 5.3.19
    Video on organizing microbiome using Excel from the Research Experiences in Microbiomes Network

    Keywords: ExcelVideoMicrobiology Educationmicrobiomesresearch in the classroomREMNeturban microbiomes

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    REMNet Tutorial, Excel Part 1: Accessing Your Microbiome Data 5.3.19
    Video on accessing microbiome data from the Research Experiences in Microbiomes Network

    Keywords: data analysisREMNet

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    Half Life of mRNA
    This module introduces exponential growth and decay in the context of understanding the stability of mRNA. It is intended for an introductory biology audience.

    Keywords: exponential equationsGenetic Informationlogarithmic equationshalf-lifemRNA

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