You are here: Home / Resources / Browse Resources

Open. Adaptable. Free.

Resources created by our members and partners.

The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

Text Search:
Applied Filters
    EvolSeq
    An Excel worksheet that simulates the molecular evolution of DNA sequences.

    Keywords: EvolutionExcelmolecular evolutionDNAResources @ ESTEEM

    1085

    views

    216

    downloads

    0

    comments

    0

    adaptations

    Creating Phylogenetic Trees from DNA Sequences
    This interactive module shows how DNA sequences can be used to infer evolutionary relationships among organisms and represent them as phylogenetic trees.

    Keywords: EvolutionHHMI BioInteractivephylogenetic tree

    1721

    views

    931

    downloads

    0

    comments

    0

    adaptations

    Functional and structural analysis of Amylase activity
    This exercise was developed to allow students to apply the scientific method and use their knowledge of enzymes to investigate the relationship between enzyme activity and structure. Students...
    899

    views

    2821

    downloads

    0

    comments

    0

    adaptations

    Bioinformatics: CpG Islands
    This is an introductory bioinformatics exercise intended for use in a genetics course.

    Keywords: geneticsepigeneticsbioinformaticsNIBLSEcpggenome database

    1483

    views

    250

    downloads

    0

    comments

    0

    adaptations

    NCBI Overview
    An overview of some of the databases within NCBI and how to get FASTA sequences.

    Keywords: videosbioinformaticsFASTAgenomicsNCBIyoutube

    989

    views

    183

    downloads

    0

    comments

    0

    adaptations

    GEA Introductory lesson on BLAST
    The "Introduction to BLAST using Human Leptin" exercise aims to introduce students to the use of the Basic Local Alignment Search Tool (BLAST) to identify related sequences and compare similarity...

    Keywords: geneticsProbabilitydatabasebioinformaticsphylogenetic analysisgenomicsBLASTProtein sequenceSimilarity searches

    1267

    views

    1075

    downloads

    0

    comments

    0

    adaptations

    DNA Barcoding & Biodiversity databases
    This resource pairs DNA barcoding databases with Biodiversity databases. Students collect their insect specimens in the field and use BLAST and BOLD to identify their species. They then use...
    925

    views

    545

    downloads

    0

    comments

    0

    adaptations

    Trout modeling example
    This is an open-ended modeling example using difference equations and Algebra II skills.

    Keywords: population biology

    832

    views

    141

    downloads

    0

    comments

    0

    adaptations

    Murder by HIV? Undergraduate edition
    Bioinformatics case study focusing on phylogenetic tree interpretation, published in the National Center for Case Study Teaching in Science

    Keywords: case studyResources @ NSF - NCCSTSbioinformaticsNIBLSEHIVnucleotide sequencingphylogenetic treeviral life cyclesmutation ratesreverse transcriptase sequences

    546

    views

    107

    downloads

    0

    comments

    0

    adaptations

    Bioinformatics: Food Detective – a Practical Guide
    This Practical Guide in the Bringing Bioinformatics into the Classroom series introduces the idea of computers as tools to help understand aspects of biology.
    673

    views

    124

    downloads

    0

    comments

    0

    adaptations

    Module 4: Removal of Introns from pre-mRNA by Splicing
    In this module, students will learn to identify splice donor and acceptor sites that are best supported by RNA-Seq data, and use the canonical splice donor and splice acceptor sequences to identify...

    Keywords: geneticsdata visualizationmolecular biologygenomicsexonintronsplicingSimilarity searchesRNA Maturation

    884

    views

    3051

    downloads

    0

    comments

    0

    adaptations

    Neochromosomes: Creating transcriptional units with yeast Golden Gate assembly
    This resource is a series of protocols using the yeast Golden Gate (yGG) method as developed by Neta Agmon and Leslie Mitchell in Jef Boeke’s lab to assemble a functional yeast gene with...
    1116

    views

    481

    downloads

    0

    comments

    0

    adaptations

    Using DNA Subway to Analyze Sequence Relationships
    This is a bioinformatics exercise using the DNA Subway Blue Line, a user-friendly pipeline of bioinformatics tools, to analyze a collection of mosquito DNA bar-code sequences.

    Keywords: phylogeneticsNIBLSEDNA BarcodingDNA sequenceBLASTmultiple sequence alignmentC1. Role of bioinformaticsC2. Computational conceptsC4. Bioinformatics toolsC5. Data retrievalC8. Data typesIncubated at NIBLSE

    2779

    views

    529

    downloads

    0

    comments

    2

    adaptations

    COVID-19: Molecular Basis of Infection-ADAPTATION
    This case was written in Spring 2020 during the COVID-19 pandemic. It focuses on understanding the structure and interaction of the SARS-Cov-2 viral spike protein that facilitates infection in...

    Keywords: infectionvaccinemolecular visualization and analysisCOVID19PDBSARS-CoVMolecular Case Study

    1101

    views

    1573

    downloads

    0

    comments

    0

    adaptations

    Databases: A Study of Influenza
    This lesson introduces the student to the Influenza Research Database. Students will select Influenza genome sequences to see how they are related. Students tests hypotheses about evolutionary...

    Keywords: Bioinformatics EducationBioinformatics and Genomicsmolecular evolutionInfluenza

    1346

    views

    518

    downloads

    0

    comments

    0

    adaptations

    Lesson IV - Comparative Genomics
    Genome Solver began as a way to teach undergraduate faculty some basic skills in bioinformatics; no coding or scripting is required. Lesson IV, Comparative Genomics, discusses some of the tools...

    Keywords: Bioinformatics EducationBioinformatics and Genomics

    1500

    views

    916

    downloads

    0

    comments

    0

    adaptations

    Using Bioinformatics Activities to understand the Past and Present of SARS-CoV2
    We have designed a Bioinformatics activity that uses tools to identify the origins and mutations in the novel SARS-CoV2 strains.
    1688

    views

    1020

    downloads

    0

    comments

    0

    adaptations

    One species, two species, red species, lead species? Phylogenetics and species concepts with Plethodon salamanders
    This lab introduces students to species concepts and basic computer-based tree-building methods using published nuclear and mitochondrial sequence data for Plethodon salamanders.

    Keywords: phylogenetic analysisTree thinkingsalamanderAudience level - Advanced UG

    1979

    views

    1573

    downloads

    0

    comments

    0

    adaptations

    Introduction to nucleotide sequence analysis and protein modeling in MEGA and PyMol using coronavirus SARS-CoV-2
    Introduction into computational approaches in phylogeny and protein modeling based on coronavirus SARS-CoV-2 (caused COVID-19 pandemic). Two self-guided tutorials for standard lab classes of 2.5...

    Keywords: phylogeneticsundergraduate educationbioinformaticsNCBICOVID19coronavirusMEGAPyMolvirtual labPDBprotein modelingSARSSARS-CoV

    1040

    views

    542

    downloads

    0

    comments

    0

    adaptations

    Molecular Basis of Sickle Cell Disease
    This multi part case on hemoglobin structure as it relates to oxygen binding and sickle cell disease focuses on utilizing bioinformatics and molecular visualization tools to learn about the sickle...

    Keywords: Hemoglobinmolecular visualization and analysisintroductory bioinformaticssickle cell diseasePDBMolecular Case Studyoxygen bindingmyoglobinmolecular literacy3D protein structuresstructural representations

    1584

    views

    1875

    downloads

    0

    comments

    0

    adaptations

    Close

    Home

    Search