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The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

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    2015-The European Bioinformatics Institute-BioModels Database
    BioModels Database is a repository of computational models of biological processes. Models described from literature are manually curated and enriched with cross-references.

    Keywords: computational biologyBioModels Databasebio databaselife science experiments

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    Phage Comparative Genomics Lab Manual
    A lab manual containing detailed instructions for several bioinformatics tools (dot plots, Phamerator maps, phylogenetic trees, and gene content similarity), all of which enable students to perform...

    Keywords: phageCUREcourse-based research experiences (CUREs)Comparative genomicsSEA-PHAGES

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    Genomics Education Alliance: Towards Genomics CURE templates
    Here we present major findings of a national survey of faculty teaching genomics CUREs conducted by the GEA, and our work on presenting relevant resources on the QUBES web portal.

    Keywords: genomicsRNAseqCURECUREscourse-based research experiences (CUREs)

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    Teaching introductory bioinformatics with Jupyter notebook-based active learning
    Presentation on teaching introductory bioinformatics with Jupyter notebook-based active learning at the 2019 Great Lakes Bioinformatics Conference

    Keywords: biostatisticsstatistical analysisavian malariaSummer Workshop 2018

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    Conference-based Undergraduate Experiences: Lowering the Barrier for Learning about Computational Biology
    Presentation on how attending conferences can enhance computational biology training for undergraduates at the 2019 Great Lakes Bioinformatics Conference

    Keywords: undergraduate educationcomputational biologyBioinformatcs

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    Exploration of the Human Genome by Investigation of Personalized SNPs
    To increase students' interest in their own genomes, this computer-based laboratory lesson is designed to be coupled with the opportunity for the students to be genotyped by the consumer sequencing...

    Keywords: bioinformaticsNIBLSECourseSourcegenomic wide association studiesUCSC genome browsersingle nucleotide polymorphism

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    Wolf Sheep Predation Simulation Exercise
    This resource is an exercise to introduce students to agent-based modeling of biological systems through working with a simple existing model.

    Keywords: simulationecologyIntroductoryNetLogoagent-based modelingagent-based modelLabbioinformaticspredator-preyUndergraduateNIBLSEInstructional SettingAudience LevelActivity LengthLess than 1 hoursimulation cycleC1. Role of bioinformaticsC6. ModelsReviewed at NIBLSEagent based modleing

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    Sequence Similarity Resource Adaptation: Exploring Ebola Virus
    This adaptation of the sequence similarity resource provides biology students with a basic set of bioinformatics concepts and tools. These concepts and tools are used to explore relationships...

    Keywords: phylogeneticsbioinformaticsEbolasequencingFASTANCBINIBLSEalgorithmsincubatorsBLASTmultiple sequence alignmentsequence similarityBLOSUM scoring matrixneighbor-joining distance matrixCourseSourcephylogram

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    Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses
    Introductory bioinformatics exercises often walk students through the use of computational tools, but often provide little understanding of what a computational tool does "under the...

    Keywords: BLASTmultiple sequence alignmentsequence similarityphylogramZika virusAlgorithmScoring Matrix

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    Using computational molecular modeling software to demonstrate how DNA mutations cause phenotypes
    This lesson is a five-week series of laboratory activities designed to help students transition from applying lower order thinking skills to the central dogma to applying higher-order thinking skills.

    Keywords: bioinformaticsNIBLSEProtein StructureDNAmolecular modelinggenotypephenotypeCourseSourcecomputational modelingcentral dogmaplant leaf structure

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    ESS: Evolutionary Stable Strategies Game Theory Module
    This Excel workbook illustrates a number of ESS examples. Each example allows the user to manipulate the initial population for each strategy and the fitness payoffs and costs for each strategy.

    Keywords: population geneticsfitnessgame theorySequence alignmentevolutionary stable strategies

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    Continuous Growth Models
    This Excel worksheet compares user-input growth data with predictions under linear, exponential, and logistic models of growth. Introduces concepts of statistical analysis that can be additionally...

    Keywords: exponential growthlogistic growthcurve fittinglinear growthgrowth models

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    Buffer Preparation
    This Excel workbook calculates the necessary components to create a buffer solution using the Henderson-Hasselbalch equation.

    Keywords: buffer solutionacidbase

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    Functional and structural analysis of Amylase activity
    This exercise was developed to allow students to apply the scientific method and use their knowledge of enzymes to investigate the relationship between enzyme activity and structure. Students...
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    MiniWorkshop Follow-Up October 2, 2020
    A follow up to our mini workshop of August 14, 2020. Further information about the python pipeline for HGT and the new cytoscape lesson.

    Keywords: Bioinformatics Education

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    Ethics in Synthetic Biology
    This collection of five activities provide students with an introduction to thinking about ethical concerns in human genome synthesis, gene editing, metabolic engineering, and synthetic genomes.

    Keywords: biostatisticsstatistical analysisavian malariaSummer Workshop 2018

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    Mini-Workshop August 14, 2020
    We reviewed the materials available on Genome Solver (other lessons here) and described our new python pipeline for examining horizontal gene transfer and a new synteny lesson in detail.

    Keywords: Bioinformatics Education

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    Lesson VII - Synteny
    The lesson teaches about synteny or the order of genes along a chromosome, which is useful for looking at orthologous genes between two species or strains.

    Keywords: Bioinformatics Education

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    Module 1: Introduction to the Genome Browser: What is a Gene?
    This lesson introduces the University of California Santa Cruz genome browser to students, walking them through some of the key features so that it can be used for analysis of gene structure.

    Keywords: geneticsbioinformaticsGenome BrowserSimilarity searchesExonsIntronsEvidence TrackStart CodonStop Codon

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    Lesson III - Annotation
    Genome Solver began as a way to teach undergraduate faculty some basic skills in bioinformatics; no coding or scripting is required. Lesson III introduces Annotation, or assigning meaning to all...
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