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The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

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    Functional and structural analysis of Amylase activity
    This exercise was developed to allow students to apply the scientific method and use their knowledge of enzymes to investigate the relationship between enzyme activity and structure. Students...
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    MiniWorkshop Follow-Up October 2, 2020
    A follow up to our mini workshop of August 14, 2020. Further information about the python pipeline for HGT and the new cytoscape lesson.

    Keywords: Bioinformatics Education

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    Understanding Frameshifting
    This module contains activities to help students understand the biology of programmed translational frameshifts (PTFs) in phages, how to identify PTFs, and how to annotate them.
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    Ethics in Synthetic Biology
    This collection of five activities provide students with an introduction to thinking about ethical concerns in human genome synthesis, gene editing, metabolic engineering, and synthetic genomes.

    Keywords: biostatisticsstatistical analysisavian malariaSummer Workshop 2018

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    Mini-Workshop August 14, 2020
    We reviewed the materials available on Genome Solver (other lessons here) and described our new python pipeline for examining horizontal gene transfer and a new synteny lesson in detail.

    Keywords: Bioinformatics Education

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    Pre-lesson: Introduction to BLAST
    Genome Solver began as a way to teach undergraduate faculty some basic skills in bioinformatics; no coding or scripting is required. This pre-lesson introduces the BLAST tool.

    Keywords: Bioinformatics EducationBioinformatics and Genomics

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    Lesson VII - Synteny
    The lesson teaches about synteny or the order of genes along a chromosome, which is useful for looking at orthologous genes between two species or strains.

    Keywords: Bioinformatics Education

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    CyVerse: Scalable Image Informatics
    Poster on cyberinfrastructure for the machine learning ere presented at the 2020 BIOME Institute: Cultivating Scientific Curiosity

    Keywords: image analysisundergraduate researchmachine learningCyVerse

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    Module 2: Transcription Part I: From DNA Sequence to Transcription Unit
    This module illustrates how a primary transcript (pre-mRNA) is synthesized using a DNA molecule as the template. Students will learn about the importance of the 5' and 3' regions of the gene for...

    Keywords: data visualizationmolecular biologybioinformaticsGenome BrowsergenomicsTranscription InitiationTranscription Start SiteTranscription Termination Signal

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    Module 1: Introduction to the Genome Browser: What is a Gene?
    This lesson introduces the University of California Santa Cruz genome browser to students, walking them through some of the key features so that it can be used for analysis of gene structure.

    Keywords: geneticsbioinformaticsGenome BrowserSimilarity searchesExonsIntronsEvidence TrackStart CodonStop Codon

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    GEA Introductory lesson on RNA-Seq
    This RNA-Seq lesson uses the CyVerse VICE Platform and Jupyter notebooks to examine the expression of the leptin gene in samples from a mouse experimental design evaluating diet (high-fat vs....

    Keywords: data sciencebioinformaticsGenome BrowserRNAseqhigh throughput sequencingmRNAAlignmentNCBI Sequence Read Archive

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    GEA Introductory lesson on BLAST
    The "Introduction to BLAST using Human Leptin" exercise aims to introduce students to the use of the Basic Local Alignment Search Tool (BLAST) to identify related sequences and compare similarity...

    Keywords: geneticsProbabilitydatabasebioinformaticsphylogenetic analysisgenomicsBLASTProtein sequenceSimilarity searches

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    Encouraging student collaboration and networking and improving student access to undergraduate research opportunities.
    We describe, as a case study, work done by two undergraduate students on a specific enzyme in the ciliate Tetrahymena thermophila.

    Keywords: undergraduate researchstudent researchenzymes

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    Genome Solver: Building faculty skills in bioinformatics
    Genome Solver (GS) began in 2011 as an NSF-funded project for faculty training in basic web-based bioinformatics skills.

    Keywords: faculty developmentbioinformaticsgenome solver

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    Genomics Education Alliance: A Collection of Posters for the 2020 BIOME Institute.
    This is a collection of posters from members of the Genomics Education Alliance (GEA) that will be presented at the 2020 BIOME Institute.

    Keywords: undergraduate researchgenomicsNIBLSEGEPgenomics educationGenomics Education AllianceGenomics Education PartnershipGEA

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    Integration of Bioinformatics into Life Science Curricula: Community Development, Dissemination, and Assessment of a NIBLSE Learning Resource
    Big data and computational tools have transformed the way we address biological questions. To prepare undergraduates for tomorrow’s challenges, life science curricula should integrate the...

    Keywords: bioinformaticsNIBLSELife Science

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    The Network for Integrating Bioinformatics into Life Sciences Education (NIBLSE): Barriers to Integration
    The Network for Integrating Bioinformatics into Life Sciences Education (NIBLSE) seeks to promote the use of bioinformatics and data science as a way to teach biology.

    Keywords: data sciencebioinformaticsNIBLSELife Science

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    Incubators: Building community networks and developing open educational resources to integrate bioinformatics into life sciences education
    To efficiently and effectively integrate bioinformatics instruction into undergraduate life science curricula, educators would benefit from open access, high-quality learning resources (LRs) for...

    Keywords: bioinformaticsNIBLSEincubatorsLife Science

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    Genomics Education Alliance: Towards Genomics CURE templates
    Here we present major findings of a national survey of faculty teaching genomics CUREs conducted by the GEA, and our work on presenting relevant resources on the QUBES web portal.

    Keywords: genomicsRNAseqCURECUREscourse-based research experiences (CUREs)

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    Making bioinformatics tools classroom-friendly
    Poster on using Cyverse resources to make classroom that make using bioinformatics in the classroom a more manageable experience presented at the 2020 BIOME Institute: Cultivating Scientific Curiosity

    Keywords: bioinformaticsJupyterJupyter notebookBLASTCyVerseRNA sequencing

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