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    BIO 439/539: Big Data Analysis
    Course materials for BIO 439/539: Big Data Analysis

    Keywords: Rdata analysisbig datadata managementstatistical methods

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    CURE-all: Large Scale Implementation of Authentic DNA Barcoding Research into First-Year Biology Curriculum
    Growing calls in science education reform have emphasized wide-scale engagement of first-year undergraduate students in authentic research experiences; however, large course enrollments, inadequate...

    Keywords: phylogeneticsbioinformaticsBiodiversityprocess of sciencetaxonomyPCRDNADNA sequencegel electrophoresis

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    An Open Source, Collaborative Electronic Notebook for Undergraduate Laboratory Classes
    To overcome many of the limitations of the paper laboratory notebook (PLN), we developed an electronic laboratory notebook (e-LN) for the Dynamic Genome course at the University of California. The...

    Keywords: data collectionData annotationNotebook Skills

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    Necessary and Sufficient? Solving the Mystery of the Mitochondrial Pyruvate Transporter
    While there are several available lessons for teaching introductory biology students about diffusion, facilitated diffusion, and active transport, fewer materials exist to support upper-division...

    Keywords: DiffusionActive transportfacilitated diffusionNecessary and sufficientTransport proteins

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    2005-JC_Sprott-Dynamical Models of Happiness
    A sequence of models for the time evolution of one’s happiness in response to external events is described.

    Keywords: happinessoscillation

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    Wenxiang 3.0
    Wenxiang diagrams illustrate protein helices as spirals on a plane and thus have the advantage over helical wheels of being planar graphs. Wenxiang 3.0 extends the original version by adding...
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    Wenxiang 3.0
    Wenxiang diagrams illustrate protein helices as spirals on a plane and thus have the advantage over helical wheels of being planar graphs. Wenxiang 3.0 extends the original version by adding...

    Keywords: bioinformaticsproteinsWenxiang

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    Wenxiang 3.0
    Wenxiang diagrams illustrate protein helices as spirals on a plane and thus have the advantage over helical wheels of being planar graphs. Wenxiang 3.0 extends the original version by adding...

    Keywords: bioinformaticsproteinsWenxiang

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    Intro to DNA Subway Blue Line
    This is a classroom tested introductory lesson & activity to introduce DNA Barcoding and DNA Subway Blue Line. It is for novices and will fit into a 1 hr 50 min lecture or lab class period.

    Keywords: phylogeneticsNIBLSEDNA BarcodingDNA sequenceBLASTmultiple sequence alignment

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    Student and Faculty Tools for Generating High-Quality Phage Annotations
    Phage genome annotation requires collaboration between faculty and their student research team. This set of resources provides tools to assist both students and faculty in the evaluation and...
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    Module 5: The Need for an Open Reading Frame
    In this module, students will learn to identify the open reading frames for a given gene, and define the phases of the splice donor and acceptor sites.

    Keywords: geneticsamino acidsmolecular biologyGenome BrowsergenomicsAssociated Protein Synthesis FactorsCodonMessenger RNARibosomestRNAs

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    The p53 Gene and Cancer
    This tutorial describes the structure and function of the p53 protein, how its activity is regulated in cells, and how mutant versions of p53 can lead to cancer.

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymolecular biologymacromoleculesGenetic disease

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    The Biology of Skin Color
    This film explores the hypothesis that different tones of skin color in humans arose as adaptations to the intensity of ultraviolet radiation in different parts of the world.

    Keywords: Resources @ HHMI - BioInteractivegene regulationgene expressionAnatomy & Physiologyhuman evolutionfilm

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    Hardy-Weinberg Equilibrium
    This module introduces the Hardy-Weinberg model in the context of understanding the population's genotype and allele frequencies. It is intended for an introductory biology audience.

    Keywords: genotypeallelesGenetics and EvolutionFrequenciesHardy-Weinberg model

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    Population Genetics: Limits to Adaptation
    This module introduces gene flow in the context of understanding the persistence of maladaptive traits in some populations. It is intended for an introductory biology audience.

    Keywords: LogarithmsAlgebraGenetics and Evolution

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    Using Undergraduate Molecular Biology Labs to Discover Targets of miRNAs in Humans
    In this lesson, we describe an easily adaptable lab module that can be used in existing undergraduate molecular biology lab courses to conduct authentic scientific research, published in CourseSource

    Keywords: molecular biologybioinformaticsNIBLSEgene regulationmicroRNAsgene expressionCourseSourcemiRNA

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    Open science, open data, open source projects for undergraduate research experiences
    Resource from the 2015 BioQUEST Summer Workshop
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    Evaluating the potential for immune escape: how likely is an antibody to protect against a specific SARS-CoV-2 variant?
    Commercial antibodies to the SARS-CoV-2 spike protein have been successfully used to treat people with COVID-19. Unfortunately, as the SARS-CoV-2 virus evolves, new variants have appeared that can...

    Keywords: course based undergraduate research experiencesBLASTmolecular modelingSARS-CoV-2antibodyNextstrainiCn3DSequence alignmentStructure alignment

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    Evaluating the potential for immune escape: how likely is an antibody to protect against a specific SARS-CoV-2 variant?
    Commercial antibodies to the SARS-CoV-2 spike protein have been successfully used to treat people with COVID-19. Unfortunately, as the SARS-CoV-2 virus evolves, new variants have appeared that can...

    Keywords: course based undergraduate research experiencesBLASTmolecular modelingSARS-CoV-2antibodyNextstrainiCn3DSequence alignmentStructure alignment

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    A Team-Based Approach to Course Development Involving Undergraduate Researchers
    Development of an undergraduate laboratory course can be a challenge, because of the need to balance both logistical and pedagogical considerations. We piloted a team-based approach to developing...

    Keywords: student researchcourse development

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